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Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges
Malignant growth is expected to surpass other significant causes of death as one of the top reasons for dismalness and mortality worldwide. According to a World Health Organization (WHO) study, this illness causes approximately between 9 and 10 million instances of deaths annually. Chemotherapy, radiation, and surgery are the three main methods of treating cancer. These methods seek to completely eradicate all cancer cells while having the fewest possible unintended impacts on healthy cell types. Owing to the lack of target selectivity, the majority of medications have substantial side effects. On the other hand, nanomaterials have transformed the identification, diagnosis, and management of cancer. Nanostructures with biomimetic properties have been grown as of late, fully intent on observing and treating the sickness. These nanostructures are expected to be consumed by growth in areas with profound disease. Furthermore, because of their extraordinary physicochemical properties, which incorporate nanoscale aspects, a more prominent surface region, explicit geometrical features, and the ability to embody different substances within or on their outside surfaces, nanostructures are remarkable nano-vehicles for conveying restorative specialists to their designated regions. This review discusses recent developments in nanostructured materials such as graphene, dendrimers, cell-penetrating peptide nanoparticles, nanoliposomes, lipid nanoparticles, magnetic nanoparticles, and nano-omics in the diagnosis and management of cancer. 2025 by the authors. -
"Community Resilience to Climate Change: Integrating Sociological Perspectives"
This review article aims to present the possible ways in which communities can be resilient to climate change as seen from sociological viewpoints. Thus, it provides a systematic review of the current literature to underscore the centrality of social capital, community networks, and cultural practices in strengthening adaptive capacities in various contexts. Bangladesh coastal people and New York City are two cases in which social capital enhances the process of preparedness, response, and recovery during disasters. Cultural knowledge and traditional coping mechanisms also enhance community resilience by learning to live with the environment and innovate in the face of climate change. Implications for policy focus on the need to incorporate sociological findings into climate change adaptation, calling for the promotion of community-based adaptation and governance structures. Issues related to the scalability of resilience interventions and socio-economic inequalities are presented and future directions for research to enhance the methodological approaches and support vulnerable populations are proposed. Thus, this review aligns with the goals of community empowering and adaptive governance to highlight sociological perspectives in creating resilience to climate change impacts. 2025 Betasciencepress Publishing. All rights reserved. -
Microplastics distribution and potential health implications of food and food products
Microplastics, miniscule plastic fragments ubiquitous in the environment, pose a growing threat as they infiltrate our food chain. This review delves into the contamination of various food categories, including seafood, agricultural products, and even processed foods through packaging and processing methods. Developing reliable analytical techniques to accurately detect microplastics levels within complex food matrices is crucial to gauge the true extent of this contamination. Although the entire range of potential health effects associated with microplastic intake is not yet known, there is reason to be concerned about the risks. These include the potential for microplastics to physically hurt the gastrointestinal tract, exposure to chemicals that seep from the polymers themselves, and the potential for microplastics to act as carriers for other dangerous compounds. This analysis identifies important knowledge gaps about the long-term health effects of microplastics exposure. It highlights the urgent need for more investigation to fully assess the possible dangers connected to microplastics in the food chain. Furthermore, it is imperative that efficient mitigation measures be put in place as soon as possible to protect food safety from microplastics contamination. More cooperation is required to create more stringent laws governing the use of plastic, investigate substitute materials for manufacturing and packaging, and create effective filtering systems for the processing of food and water. Through devoted research to close knowledge gaps and the implementation of strong mitigation strategies, can make proactive efforts to safeguard public health and maintain the integrity of our food supply chain for future generations. 2024 Elsevier Inc. -
Addressing psychosocial problems associated with the COVID-19 lockdown
The lockdown imposed by the governments of various countries to contain the spread of the coronavirus disease (COVID-19) is associated with various psychosocial problems. The complications within the family and time management issues that can occur during this time period are explored. The stigma and anxiety associated with the coronavirus disease are also addressed. It is noted that the problems faced by vulnerable communities including individuals with substance use disorder (SUD) tend to be ignored. These crucial areas that psychologists and mental health professionals should consider before providing intervention are discussed. 2020 Elsevier B.V. -
Platelets to surrogate lung inflammation in COVID-19 patients
The neoteric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been jeopardizing the world with the symptoms of seasonal flu. The virus contagion predicted to have been originated from Wuhan, China has by far trapped 4,198,418 cases from 212 countries in the world with two international conveyances with 284,102 deaths as of 11 May 2020 (10:18 GMT). Researchers around the globe have indulged in deciphering viral mode in the body for devising a cure. Affirmations from autopsies and preliminary findings on SARS-CoV-2 hypothesized on viral pathogenesis within the host, for instance, source of inflammation in lungs and pneumonia. This hypothesis assigns the platelets as agents of infection after viral entry. Presently, curbing infection to stall the spread of SARS-CoV-2 is the prima facie intervention employed, worldwide. However, public health authorities must monitor the state of affairs scrupulously, as the deeper our understanding of this novel virus and its associated outbreak, the better we can deal with it. Knowing this idea might be far-fetched, yet this postulate would serve as the groundwork for the present situation. 2020 Elsevier Ltd -
Limelight in Dark Times: Jyoti Kumari's 'Cyclothon'
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Suicide among children during Covid-19 pandemic: An alarming social issue
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Hike in student suicides Consequence of online classes?
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Work from home in the pandemic era: Loss of mental equilibrium?
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Can bot be my mental health therapist? A pandemic panorama
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Work from home during covid-19-disequilibrium of mental health and well-being among employees
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Migrant labour and mobile sensibilities
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Battle fatigue of Covid 19 warriors Heal the healers
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BTS: Belonging and Becoming
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Frontline medical professionals in distress - Doctor heal thyself
Covid has changed our lives in many ways. People are scared to even step out of their houses, but health care workers have no option but to continue to work and care for the sick. Health care workers play a vital role in providing care to the infected persons, working beyond their capacities and risking their own lives. There is a lot of stress involved in the medical profession, and the pandemic made it worse. Each frontline health worker is at risk of getting infected with Covid during work and carrying it to their families, causing a lot of anxiety and mental health issues among the health care workers. According to a recent by the US Centers for Disease Control and Prevention (CDC), more than half of public health workers have reported symptoms of at least one mental health condition like depression, anxiety, and post-traumatic stress disorder (PTSD) in the recent past. A recent study among 422 doctors revealed 63.5% symptoms of depression, and 45% symptoms of stress, among frontline COVID-19 doctors. Physicians who perceived organizational problems related to procedural and informational justice were exposed to high levels of occupational stress. Every physician should have a personal doctor, and he or she has to seek suitable help as needed. The health care workers' stress is mainly associated with work stress as they are expected to work on a war footing and get very little time to spend with their families. There is a need to set up good psychiatric care for the medical professionals in the hospitals. The administrators of the hospitals should frequently check on the health and well-being of their employees. This article attempts to provide strategies to hospital administrators to help medical professionals reduce their stress levels. 2022 -
A machine learning model to predict suicidal tendencies in students
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Contradictions in conservation: Indias forest (Conservation) Amendment Bill, 2023
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Villains and Their Logic in Contemporary Films
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Making the body public: Implications of the new standards of body-image
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