Fractional and memory effects on wave reflection in pre-stressed microstructured solids with dual porosity
subject: Dual porosity; Fractional-order derivative; Memory-dependent derivative; Microstructure; Nonlocal elasticity; Plane waves
description: The present work investigates the influence of fractional-order derivative and memory-dependent derivative on the behavior of various waves reflected at the free surface of a size-dependent, pre-stressed, microstructured thermoelastic solid with a dual porosity framework. A generalized MooreGibsonThomson (MGT) model, incorporating higher-order terms and memory effects, is adopted to describe the complex heat transfer behavior within the material. A nonlocal framework based on Eringen's theory is utilized to derive the basic relations of the considered medium. An examination of the non-dimensionalized governing equations is conducted employing the normal mode technique to provide accurate solutions. The research demonstrates the presence of six separate wave modes that travel at varying speeds within the medium. The energy and amplitude ratios of reflected waves are determined by applying suitable boundary conditions. The influence of varying incidence angles on the reflected wave energy distribution is investigated numerically and visualized using MATLAB software. The study reveals that the energy ratios of the reflected waves are sensitive to the fractional-order parameter, kernel functions, initial stress, and nonlocality parameter. The analysis suggests a conservative reflection process, indicating minimal energy loss during reflection. Key findings and their implications for relevant scenarios are presented in the conclusion. Comparisons with existing models for certain cases demonstrate good agreement, supporting the validity of the present model. 2025 Elsevier Masson SAS
creator: Das S.; Dutta R.; Gupta V.; Singhal A.; Barak M.S.; Almohsen B.
source: European Journal of Mechanics, A/Solids, Vol-111
publisher: Elsevier Ltd
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 9977538; CODEN: EJASE
format: Online
language: English
type: Article
coverage: Das S., School of Physical Sciences, Amrita Vishwa Vidyapeetham, Mysuru campus, Karnataka, India; Dutta R., Amrita School of Computing, Amrita Vishwa Vidyapeetham, Mysuru campus, Karnataka, India; Gupta V., Department of Mathematics, Indira Gandhi University, Meerpur, Haryana, Rewari, India, Department of Mathematics, Gurugram University, Gurugram, India; Singhal A., Department of Mathematics, Christ University, Karnataka, Bengaluru, India; Barak M.S., Department of Mathematics, Indira Gandhi University, Meerpur, Haryana, Rewari, India; Almohsen B., Department of Mathematics, College of Science, King Saud University, P.O. Box 2455, Riyadh, 11451, Saudi Arabia

Construction of a waste-derived graphite electrode integrated IL/Ni-MOF flowers/Co3O4 NDs for specific enrichment and signal amplification to detect aspartame
subject: Aspartame; Co3O4 NDs; Food samples; Graphite electrode; Ionic liquid; Ni-MOF; Sensor
description: A novel and cost-efficient electrochemical sensor was designed by immobilizing IL/Ni-MOF/Co3O4 nanodiamonds on the graphite (GE) electrode, marking the first application for the detection of aspartame. The graphite electrode was extracted and recycled from discharged batteries to serve as a working electrode. The nanocomposite features unique Co3O4 nanodiamonds, generated using Coriandrum sativum seed extract, alongside Ni-metal organic framework (MOF), which were synthesized through a solvothermal method. The conductivity and stability of the electrochemical sensor were enhanced through the incorporation of the ionic liquid (IL) ([BMIM][MeSO4]. The phytochemical profile of Coriandrum sativum seed extract, analyzed by GC-MS, identified key compounds involved in the synthesis of Co3O4 nanodiamonds. A comprehensive characterization of the nanocomposite was performed using UV-Vis, FTIR, DLS, Zeta potential, XRD, XPS, FE-SEM, TEM, optical profilometry, and AFM to confirm the structural and elemental modifications. Electrochemical characterization of the bare and modified electrodes was conducted through cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The GE/IL/Ni-MOF/Co3O4 nanodiamonds modified electrode displayed enhanced electroanalytical performance for aspartame detection, characterized by signal amplification at +7.0 V. Quantitative analysis by Differential Pulse Voltammetry (DPV) and Square Wave Voltammetry (SWV) revealed a linear detection range of 315 M for aspartame. A comparison of SWV and DPV revealed superior analytical performance for SWV, with limit of detection (LOD) and limit of quantification (LOQ) values of 1.02 M and 3.1 M (R2 = 0.993) compared to 1.81 M and 5.5 M (R2 = 0.986) for DPV. This study reveals the excellent adsorption capabilities of Ni-MOF and Co3O4 nanodiamonds (Co3O4 NDs), attributed to their high porosity and large surface area, paving the way for the development of affordable sensing devices for artificial swe…
creator: Manuel M.; Kanchi S.
source: Colloids and Surfaces A: Physicochemical and Engineering Aspects, Vol-705
publisher: Elsevier B.V.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 9277757; CODEN: CPEAE
format: Online
language: English
type: Article
coverage: Manuel M., Department of Chemistry, CHRIST University, Bengaluru, 560 029, India; Kanchi S., Department of Chemistry, CHRIST University, Bengaluru, 560 029, India

One-pot sustainable synthesis of novel pyrido[2,3-d]pyrimidinones and their evaluation for antitubercular and anticancer activity
subject: Anticancer activity; Antitubercular activity; MCR; Pyrido[2,3-d]pyrimidinones; Sustainable synthesis; ?-proline
description: A novel green protocol for the construction of diversified pyrido[2,3-d]pyrimidinones was accomplished by a single-pot reaction of aryl aldehydes, Meldrum's acid, thiobarbituric acid, and ammonium acetate/aniline in H2O using ?-proline as an expeditious reusable catalyst at room temperature (26 C). Our strategy provides an innovative synthetic avenue for the construction of pyrido[2,3-d]pyrimidinones, as well as several advantages over traditional methods, including a simple procedure, shorter reaction duration, excellent yields, safe handling, easy workup, catalyst recovery, and environmental compatibility. Furthermore, the synthesised compounds were tested for their impact on different cell lines and microorganisms. Compounds 5d and 5e were particularly effective against Mycobacterium tuberculosis (antitubercular), human breast cancer cells (MCF-7), lung cancer cells (A549 and NCI-H460), and both Gram-positive (S. pyogenes) and Gram-negative (E. coli) bacteria. The derivatives with hydroxyl and nitro substitutions [5e, 5f] showed the highest potency against MCF-7, A549, and NCI-H460 cell lines, with IC50 values of 3.684.36, 3.823.41, and 11.3412.28 g/mL, respectively. 2024 The Author(s)
creator: Tabassum S.; Ramaraj S.G.; Rajprasad J.; Sadaiyandi V.; Kumar N.; Govindaraju S.
source: Journal of Organometallic Chemistry, Vol-1025
publisher: Elsevier B.V.
date: 2025-01-01
rights: All Open Access; Hybrid Gold Open Access
relation: ISSN: 0022328X; CODEN: JORCA
format: Online
language: English
type: Article
coverage: Tabassum S., Department of Chemistry, Surana College - Autonomous, South End Road, Basavanagudi, Bengaluru, 560004, India; Ramaraj S.G., Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Japan, Department of Materials Physics, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMTS), Thandalam, Tamilnadu, Chennai, 602105, India; Rajprasad J., Department of Civil Engineering, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, 603203, India; Sadaiyandi V., Department of Physics and Nanotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamilnadu, Chengalpattu, 603203, India; Kumar N., Department of Electronics & Communication Engineering, Graphic Era Deemed to be University, Uttarakhand, Dehradun, 248002, India; Govindaraju S., Department of Sciences and Humanities, School of Engineering and Technology, Christ University, Mysore Road, Bengaluru, 560074, India

Optimized Multi-Scale Attention Convolutional Neural Network for Micro-Grid Energy Management System Employing in Internet of Things
subject: convolutional neural network; ensemble Kalman filter; fault detection; internet of things; microgrid energy management; sheep flock optimization
description: The combination of micro-grid energy management systems (EMSs) with the Internet of Things (IoT) offers a promising way to improve energy use and distribution. However, challenges such as device compatibility and the difficulty of managing energy efficiently make it hard to implement these systems effectively. This study offers a significant advancement in energy management by using IoT for microgrid systems. An Optimized Multi-scale Attention Convolutional Neural Network for microgrid EMS employing IoT (OMACNN-MGEMS-IoT) is proposed in this study, which enables efficient monitoring and control of energy resources. The proposed model's input data are gathered from the MQTT dataset. This research employs a Regularized Bias-aware Ensemble Kalman Filter (RBAEKF) for pre-processing input data, ensuring the removal of outliers and updating missing values. The MACNN is then used for effective fault detection within the microgrid. To enhance its performance, the Sheep Flock Optimization Algorithm (SFOA) is introduced to optimize the MACNN parameters, ensuring accurate fault detection. Implemented on the MATLAB platform, the performance of the OMACNN-MGEMS-IoT method is assessed through various performance metrics, demonstrating significant improvements. Notably, the proposed method achieves higher cost reductions of 25%, 22%, and 26% compared to existing approaches such as the IoT platform for energy management in multi-micro grid systems (IoT-PEM-MMS), a micro-grid system infrastructure implementing IoT for efficient energy management in buildings (MSII-IoT-EEM) and a hybrid deep learning-based online energy management scheme for industrial microgrids (HDL-OEM-IM). The findings highlight the impact of the proposed OMACNN-MGEMS-IoT method in enhancing energy efficiency and cost-effectiveness in microgrid systems. 2025 John Wiley & Sons Ltd.
creator: Vetriveeran D.; Sambandam R.K.; Sekar T.; Venkatachalam A.
source: Optimal Control Applications and Methods
publisher: John Wiley and Sons Ltd
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 1432087; CODEN: OCAMD
format: Online
language: English
type: Article
coverage: Vetriveeran D., Department of Computer Science and Engineering, Christ University, Bangalore, India; Sambandam R.K., Department of Computer Science and Engineering, Christ University, Bangalore, India; Sekar T., Department of Computer Science and Engineering, Bharath Institute of Higher Education and Research, Chennai, India; Venkatachalam A., Department of Computer Science and Engineering, Christ University, Bangalore, India

Unveiling the Redox Characteristics of Rutin Trihydrate-Canvas-Based Sensor for Hydrazine Sensing in Water Samples
description: The inclusion of redox mediators into electrocatalytic systems facilitates rapid electron shuttling kinetics and boosts the overall catalytic performance of the electrode. This approach overcomes the sluggish reaction dynamics associated with direct electron transfer, which may be impeded by restricted analyte access to the electrodes active sites. In contrast to conventional synthetic redox mediators, naturally sourced phytomolecule rutin trihydrate (RT), extracted from apple juice, offers potential ecological advantages. This bands with green chemistry principles and sustainability in electroanalytical approaches. The current work presents an eco-friendly and direct electrochemical approach to fabricate a redox-active RT-immobilized MWCNT-infused PEDOT hybrid material-modified glassy carbon electrode (GCE/MWCNT + PEDOT@RT). The developed electrode showcased a sharp and stable redox signal at E0 = 0.63 V vs Ag/AgCl with no surface-fouling characteristics. The efficacious functionalization of RT onto MWCNT + PEDOT was corroborated by a remarkable increase in the surface characteristics, enhanced electrochemical current responses, and low charge transfer resistance. The GCE/MWCNT + PEDOT@RT exhibited highly selective and sensitive sensing responses toward the toxic and potentially carcinogenic hydrazine (HZ) via cyclic voltammetry and differential pulse voltammetry techniques, yielding a low detection limit (DL) of 1.02 ?M and a sensitivity of 0.032 ?A ?M-1 in a linear dynamic range between 0 and 1350 ?M. In addition, the method was highly efficient for HZ detection in real samples of tanker, tap, and wastewater samples, producing a good recovery of ?98%. 2025 American Chemical Society.
creator: Gandhi M.; Sariga N.; Varghese A.
source: Langmuir
publisher: American Chemical Society
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 7437463; CODEN: LANGD
format: Online
language: English
type: Article
coverage: Gandhi M., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India; Sariga N., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India; Varghese A., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India

Facile synthesis of Bi2WO6-NiO nanocomposite for supercapacitor application
subject: Cyclic voltammetry; Energy conversion and storage; High energy density; Supercapacitor
description: In order to prepare for future high-power storage-related applications, a tremendous amount of studies have been conducted on the manufacturing of high-performance supercapacitor electrodes. The hydrothermal technique was used to synthesize Bi2WO6NiO nanocomposite (NC), which was examined using FTIR, XRD, HR-TEM, EDX, FESEM, and XPS techniques. Furthermore, the Bi2WO6-NiO NC performs with an elevated specific capacity of 398.2C/g at 10 mV/s. The charge transfer resistance (Rct) and solution resistance (Rs) of Bi2WO6-NiO NC were determined as 0.81 and 0.23 ? using electrochemical impedance spectra (EIS). Bi2WO6-NiO NC extended the chargedischarge time and rate capacities, as shown by the galvanostatic chargedischarge (GCD) analysis. Even after 2000 cycles, Bi2WO6-NiO NC cyclic stability was superior with a capacitive retention of 89.3 %. A power density of 6750 W/kg resulted from the constructed asymmetric supercapacitor (ASC) device based on Bi2WO6-NiO/AC, exhibiting an energy density of 32.5 Wh/kg. Additionally, the ASC maintains high cyclic stability with 90.8 % of initial capacity, even after 2000 chargedischarge cycles in a row. 2024 Elsevier B.V.
creator: Chelladurai A.; Veerasingam M.; Kesavan T.; Alotaibi N.H.; Sangaraju S.; Muthusamy K.K.; Sonaimuthu M.; Sakkarapani S.
source: Materials Science and Engineering: B, Vol-313
publisher: Elsevier Ltd
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 9215107; CODEN: MSBTE
format: Online
language: English
type: Article
coverage: Chelladurai A., Department of Physics, Alagappa University, Tamilnadu, Karaikudi, 630 003, India; Veerasingam M., Department of Chemistry, Mount Zion College of Engineering and Technology, Thirumayam, Pudukkottai, 622 507, India; Kesavan T., Department of Physics, Bharath Institute of Higher Education and Research, Chennai, 600073, India; Alotaibi N.H., Department of Chemistry, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia; Sangaraju S., National Water and Energy Center, United Arab Emirates University, Al Ain, 15551, United Arab Emirates; Muthusamy K.K., Department of Physics and Electronics, CHRIST University, Bengaluru, 560 029, India; Sonaimuthu M., School of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, South Korea; Sakkarapani S., Department of Physics, Alagappa University, Tamilnadu, Karaikudi, 630 003, India

Fabrication of cobalt oxide@cellulose/nitrogen doped carbon nanotubes decorated metal organic frameworks composite for symmetric supercapacitor applications
subject: Cellulose (CE); Cobalt oxides; Composite; Hydrothermal process; Nitrogen doped MWCNT; Symmetric supercapacitor (SSC); Zeolite imidazole frame work (ZIF-67)
description: The two main issues facing the world's population now are energy storage needs and environmental protection. A lot of work has gone into creating electrochemical energy storage using chemical processes and a variety of possible electrode active materials. Supercapacitors, which are energy storage devices with a unique structure and morphology of cellulose materials for green energy resource. In this regard, solid state hydrothermal process is used to fabricate Co3O4@Cellulose (CE), Co3O4@CE/N-MWCNT, and Co3O4@CE/N-MWCNT/ZIF-67 composite materials. XRD, XPS, BET, and HR-TEM analyses verified the structural, surface, and morphological analysis. The electrochemical studies by a three- and two-electrode fabrication in presence of 1M KOH electrolyte for supercapacitor applications. When 1M KOH electrolyte is present, the fabricated Co3O4@CE/N-MWCNT/ZIF-67composite electrode displayed exceptional cyclic stability and a specific capacitance of ?835 F g?1 at 1 A/g. The constructed composite electrodes of Co3O4, Co3O4@CE, and Co3O4@CE/N-MWCNT have specific capacitances of 263, 406, and 576 F g?1 at 1 A/g, respectively, which improves electrochemical properties using a three-electrode design. The Co3O4@CE-N-MWCNT/ZIF-67//1MKOH/SSC composite is produced using two electrode configurations. The final material showed a capacitance of 258 F g?1 at 1 A/g, a capacitance retention of 84.95 % across 8000 cycles, and an energy density of 30.99 W h kg?1 at a power density of 5409 W kg?1. Hence, the composite electrodes that have been produced have the potential to be used in electrochemical systems. 2025 Elsevier B.V.
creator: Ramesh S.; Rabani I.; Indumathi T.; Yadav H.M.; Selvaraj M.; Pai Sunajadevi K.R.; Seo Y.-S.; Kim J.-H.; Kim H.S.
source: Journal of Power Sources, Vol-631
publisher: Elsevier B.V.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 3787753; CODEN: JPSOD
format: Online
language: English
type: Article
coverage: Ramesh S., Department of Mechanical, Robotics and Energy Engineering, Dongguk University, 30, Pil-dong, Jung-gu, Seoul, 04620, South Korea; Rabani I., Interface Lab, Department of Nanotechnology and Advanced Materials Engineering, Sejong University, Seoul, 05006, South Korea; Indumathi T., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India; Yadav H.M., School of Nanoscience and Bio-Technology, Shivaji University, Kolhapur, 416004, India; Selvaraj M., Department of Chemistry, Faculty of Science, King Khalid University, Abha, 61413, Saudi Arabia, Research Center for Advanced Materials Science (RCAMS), King Khalid University, PO.Box 9004, Abha, 61413, Saudi Arabia; Pai Sunajadevi K.R., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India; Seo Y.-S., Interface Lab, Department of Nanotechnology and Advanced Materials Engineering, Sejong University, Seoul, 05006, South Korea; Kim J.-H., Department of Mechanical Engineering, Inha University, Inha-ro,100, Namgu, Incheon, 22212, South Korea; Kim H.S., Department of Mechanical, Robotics and Energy Engineering, Dongguk University, 30, Pil-dong, Jung-gu, Seoul, 04620, South Korea

Engineering CoMn2O? nanofibers: Enhancing one-dimensional electrode materials for high-performance supercapacitors
subject: Electrospinning; Nanofibers; One dimensional; Supercapacitor; Symmetric device
description: One-dimensional CoMn2O4 nanofibers were developed via the electrospinning method, offers a novel approach for designing electrode materials for energy storage device -supercapacitors. Field emission scanning electron microscopy (FESEM) with EDX confirmed the highly porous CoMn2O4 phase with desired composition. Elemental mapping studies confirmed uniform distribution of Co, Mn, and O elements throughout the nanofibers.Electrochemical studies underscored the crucial role of structural voids and spacing in enhancing energy storage capacity, establishing CoMn2O4 as a promising electrode material. Specific energy and power studies yielded remarkable results of 93.84 Whr/kg and 55.20 kW/kg, respectively. Additionally, specific capacitance determination returned 937.42 F/g, indicating exceptional charging and discharging performance over 1000 cycles with 93.3 % capacitance retention. Moreover, the flexible symmetric supercapacitor is expected to demonstrate exceptional flexibility and electrochemical stability, achieving a specific energy of 232 Wh/kg and a specific power of 84 kW/kg at a current density of 1 mA/cm. These findings advance our understanding of CoMn2O4 nanofibers and offer insights into developing efficient and stable energy storage systems for diverse applications. 2025 Elsevier B.V.
creator: Jirankalagi S.N.; Molane A.C.; Sutar S.M.; Mulik R.N.; Selvaraj M.; Sunajadevi K.R.P.; Patil V.B.
source: Synthetic Metals, Vol-311
publisher: Elsevier Ltd
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 3796779; CODEN: SYMED
format: Online
language: English
type: Article
coverage: Jirankalagi S.N., Functional Materials Research Laboratory, School of Physical Sciences, PAH Solapur University, MS, Solapur, 413255, India, Department of Physics, DBF Dayanand College of Arts & Science, MS, Solapur, 413002, India; Molane A.C., Functional Materials Research Laboratory, School of Physical Sciences, PAH Solapur University, MS, Solapur, 413255, India; Sutar S.M., Functional Materials Research Laboratory, School of Physical Sciences, PAH Solapur University, MS, Solapur, 413255, India; Mulik R.N., Department of Physics, DBF Dayanand College of Arts & Science, MS, Solapur, 413002, India; Selvaraj M., Central Labs, King Khalid University, Abha, AlQura'a, P.O. Box 960, Saudi Arabia, Department of Chemistry, Faculty of Science, King Khalid University, Abha, 61413, Saudi Arabia; Sunajadevi K.R.P., Department of Chemistry, Christ University, Karnataka, Bangalore, 560029, India; Patil V.B., Functional Materials Research Laboratory, School of Physical Sciences, PAH Solapur University, MS, Solapur, 413255, India

Interplay of financial inclusion and economic growth in emerging economies
subject: Digital financial inclusion; Economic growth; Emerging economies; Fiscal policy; Monetary policy; Panel data analysis
description: This study delves into the complex link between financial inclusionboth traditional and digitaland economic growth across emerging economies from 1990 to 2022, using Dynamic Simulated ARDL and Driscoll-Kraay Standard Error techniques. Key findings highlight that traditional financial inclusion correlates positively with economic growth, whereas digital financial inclusion presents obstacles. Additionally, fiscal, monetary, and trade policies play vital roles: fiscal policies in Brazil, Colombia, and Mexico focus on infrastructure, social programs, and tax reforms, respectively, to spur growth. Monetary policies include Brazil's inflation targeting, Turkey's interest rate adjustments, and India's MUDRA scheme, which promotes entrepreneurship. Trade policies, such as Chile's Free Trade Agreements and Mexico's participation in NAFTA, improve market access and economic resilience, while Egypt and Saudi Arabia focus on foreign direct investment and economic diversification. The study emphasizes coordinated policy efforts for sustained growth, advocating for financial inclusion supported by robust regulations and government investments in critical areas like infrastructure and healthcare. Central banks contribute by maintaining price stability and credit access, while strategic trade agreements and export diversification enhance economic resilience. The focus of the study on emerging economies and macro-level insights calls for further research at the micro-level to refine these results. By maintaining policy coherence and regular evaluations, these strategies aim to foster inclusive, long-term economic growth. 2025 The Author(s)
creator: Pal S.; Vankila S.; Fernandes M.N.
source: World Development Sustainability, Vol-6
publisher: Elsevier B.V.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 2772655X
format: Online
language: English
type: Article
coverage: Pal S., Indian Institute of Plantation Management-Bengaluru (IIPMB) Campus P.O, Jnana Bharathi, Mallathahalli, Karnataka, Bengaluru, 560056, India, School of Business and Management, Christ University, Bangalore, India, Department of Humanities and Social Sciences, Indian Institute of Technology, West Bengal, Kharagpur, 721302, India; Vankila S., School of Business and Management, Christ University, Bangalore, India; Fernandes M.N., School of Business and Management, Christ University, Bangalore, India

Study of multilayer flow of non-Newtonian fluid sandwiched between nanofluids
subject: Differential transform method; Entropy generation analysis; Hybrid nanofluid; Multilayer flow; Nonlinear Boussinesq approximation; Third-grade fluid
description: This theoretical investigation examines the nonlinear convective heat transport and multilayer flow of a non-Newtonian fluid within a vertical slab, incorporating viscous heating effects. The middle layer of the slab contains a third-grade fluid, while the outer layers are filled with a water-based Ag-MgO hybrid nanoliquid. Continuity in temperature, heat flux, velocity, and shear stress is maintained at the interfaces of the fluid layers. The thermal buoyancy force is modeled using the nonlinear Boussinesq approximation. The governing system comprises conservation equations for mass, momentum (Navier-Stokes), and energy for each of the three layers. These differential equations are non-dimensionalized, and the resulting dimensionless four-point nonlinear boundary value problem is transformed into a two-point boundary value problem before being solved numerically. For limiting cases, analytical and semi-analytical solutions are computed and used as benchmark results to validate the numerical method employed. Entropy generation analysis indicates that higher third-grade fluid parameters reduce the magnitude of velocity and temperature fields, as well as entropy production across all regions. The third-grade fluid parameter shows a decreasing influence on velocity and temperature fields throughout the system. The continuity of interfacial conditions induces a dragging effect; despite the absence of third-grade fluid parameters in regions I and III, their influence is apparent in these regions. The Bejan number slightly decreases at the walls with increasing third-grade fluid parameters, exhibiting a dual effect in the third-grade fluid layer. Near the walls, the Bejan number decreases as the nanoparticle volume fraction increases. Findings of this work may have applications in polymer industries and processes involving high temperatures. 2024
creator: Myson S.; Basavarajappa M.; Vajravelu K.
source: Partial Differential Equations in Applied Mathematics, Vol-13
publisher: Elsevier B.V.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 26668181
format: Online
language: English
type: Article
coverage: Myson S., Center for Mathematical Needs, Department of Mathematics, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Basavarajappa M., Center for Mathematical Needs, Department of Mathematics, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India, Department of Mathematics and Physics, Texas A&M International University, Laredo, 78041, TX, United States; Vajravelu K., Department of Mathematics, University of Central Florida, Orlando, 32816, FL, United States

2D Materials Coated Flexible Origami for Low-Frequency Energy Harvesting
subject: 2D materials; DFT; origami structures; paper; wave energy
description: Wave energy is one of the most abundant energy sources. Triboelectric nanogenerators (TENGs) are becoming more popular for sustainable energy generation from waves. Concerning the renewable energy demands, we focus on developing cost-effective and adaptable origami-TENGs (O-TENGs) for harvesting wave energy, specifically utilizing paper-based (cellulose) materials. An origami-inspired lightweight and scalable design is proposed to create high-performance O-TENGs suitable for the complex conditions of low-frequency wave excitation. The paper-based spring-like O-TENG is coated with two-dimensional (2D) molybdenum disulfide (MoS2) nanosheets and demonstrates efficacy in harvesting mechanical energy in the ambient environment and the output performance compared with reduced graphene oxides (rGO). A detailed density functional theory (DFT) calculation was used to analyze the charge transfer mechanism in the coated origami structures. Furthermore, a barrel-shaped floating generator incorporating multiple origami TENGs is introduced to capture ocean wave energy across various frequencies, amplitudes, and directional movements. Since the coated origami structures show a good self-rebounding spring-like nature and energy harvesting properties, they are suitable for blue energy harvesting. 2025 American Chemical Society.
creator: Kumbhakar P.; Mishra S.; Nayak P.V.; Sunny A.; Singh A.K.
source: ACS Applied Electronic Materials
publisher: American Chemical Society
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 26376113
format: Online
language: English
type: Article
coverage: Kumbhakar P., Department of Physics and Electronics, CHRIST (Deemed to be University), Bangalore, 560029, India; Mishra S., Materials Research Centre, Indian Institute of Science, Karnataka, Bangalore, 560012, India; Nayak P.V., Department of Physics and Electronics, CHRIST (Deemed to be University), Bangalore, 560029, India; Sunny A., Department of Physics and Electronics, CHRIST (Deemed to be University), Bangalore, 560029, India; Singh A.K., Materials Research Centre, Indian Institute of Science, Karnataka, Bangalore, 560012, India

Probing the formation of megaparsec-scale giant radio galaxies: I. Dynamical insights from magnetohydrodynamic simulations
subject: Galaxies: active; Galaxies: groups: general; Galaxies: jets; Magnetohydrodynamics (MHD); Methods: numerical
description: Context. Constituting a relatively small fraction of the extended-jetted population, giant radio galaxies (GRGs) form in a wide range of jet and environment configurations. This observed diversity complicates the identification of the growth factors that facilitate their attainment of megaparsec scales. Aims. This study aims to numerically investigate the hypothesized formation mechanisms of GRGs extending ?1 Mpc in order to assess their general applicability. Methods. We employed tri-axial ambient medium settings to generate varying levels of jet frustration and simulated jets with a low and a high power from different locations in the environment. This approach formulated five representations evolving under a relativistic magnetohydrodynamic framework. Results. The emergence of distinct giant phases in all five simulated scenarios suggests that GRGs may be more common than previously believed. This prediction can be verified with contemporary and forthcoming radio telescopes. We find that different combinations of jet morphology, power, and evolutionary age of the formed structure hold the potential to elucidate different formation scenarios. In all of these cases, the lobes are overpressured, prompting further investigation into pressure profiles when jet activity ceases, potentially distinguishing between relic and active GRGs. We observed a potential phase transition in GRGs marked by differences in lobe expansion speed and pressure variations compared to their smaller evolutionary phases. This suggests the need for further investigation across a broader parameter space to determine if lobe evolution in GRGs fundamentally differs from smaller radio galaxies. The axial ratio analysis reveals self-similar expansion in rapidly propagating jets, while there is a notable deviation when the jet forms wider lobes. Overall, this study emphasizes that multiple growth factors simultaneously at work can better elucidate the current-day population of GRGs, including scenar…
creator: Giri G.; Bagchi J.; Thorat K.; Deane R.P.; Delhaize J.; Saikia D.J.
source: Astronomy and Astrophysics, Vol-693
publisher: EDP Sciences
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 46361; CODEN: AAEJA
format: Online
language: English
type: Article
coverage: Giri G., Department of Physics, University of Pretoria, Private Bag X20, Hatfield, 0028, South Africa, South African Radio Astronomy Observatory, 2 Fir St, Black River Park, Observatory, 7925, South Africa; Bagchi J., Department of Physics and Electronics, Christ University, Hosur Road, Bangalore, 560029, India; Thorat K., Department of Physics, University of Pretoria, Private Bag X20, Hatfield, 0028, South Africa; Deane R.P., Department of Physics, University of Pretoria, Private Bag X20, Hatfield, 0028, South Africa, Wits Centre for Astrophysics, School of Physics, University of the Witwatersrand, 1 Jan Smuts Avenue, Johannesburg, 2000, South Africa; Delhaize J., Department of Astronomy, University of Cape Town, Private Bag X3, Rondebosch, 7701, South Africa; Saikia D.J., Inter-University Centre for Astronomy and Astrophysics, Post Bag 4, Pune, 411007, India

Parametric analysis for thermally magnetized hybrid ternary (TMHT) nanofluid flow on thin film with temperature stratification
subject: Heat transfer; Magnetic field; Stretched surface; Temperature stratification; Ternary nanofluid
description: The thermophysical examination of flow field claims various applications in both scientific and industrial domains and hence it remains important to inspect especially when both the heat and mass transfer are taken simultaneously. Owning such motivation, the present study offers a response surface optimization for thermal flow field of hybrid ternary water-based aluminium, silicon and Zinc nanofluid over a stretched surface manifested with both temperature stratification and concentration stratification effects. The governing equations are formulated for mathematical model and those PDE's are reduced to ODE's by using appropriate similarity transformations. Those obtained resultant equations are solved numerically by using Runge Kutta Fehlberg fourth fifth-order (RKF 45) technique. The supremacy of essential aspects on the flow field, heat and mass transfer rates were analyzed using graphical representation. Additionally, Response surface Methodology is performed to derived the heat transfer rate as a response function for the input factors for different parameters. From the graph it is noticed that temperature profile drops as the thermal stratification parameter increases. The temperature admits the direct relation with an increase in the solid volume fraction of ternary nanofluids. From RSM it is noticed that adjusted R-squared and R-squared are obtained as 100 % accuracy of the mathematical model. 2025 The Author(s)
creator: N T.T.; L K.; Rehman K.U.; Varma S.V.K.; Shatanawi W.; Kumar G.V.; Asghar Z.
source: International Journal of Thermofluids, Vol-26
publisher: Elsevier B.V.
date: 2025-01-01
rights: All Open Access; Gold Open Access
relation: ISSN: 26662027
format: Online
language: English
type: Article
coverage: N T.T., Department of Mathematics, School of Applied Sciences, REVA University, Karnataka, Bengaluru, India, Department of Mathematics, CHRIST (Deemed to be University), Bengaluru, India; L K., Department of Mathematics, School of Applied Sciences, REVA University, Karnataka, Bengaluru, India; Rehman K.U., Department of Mathematics and Sciences, College of Humanities and Sciences, Prince Sultan University, Riyadh, 11586, Saudi Arabia; Varma S.V.K., Department of Mathematics, School of Applied Sciences, REVA University, Karnataka, Bengaluru, India; Shatanawi W., Department of Mathematics and Sciences, College of Humanities and Sciences, Prince Sultan University, Riyadh, 11586, Saudi Arabia, Department of Mathematics, Faculty of Science, The Hashemite University, P.O. Box 330127, Zarqa, 13133, Jordan; Kumar G.V., Department of Mathematics, CSSR & SRRM Degree & PG College, A.P., Kamalapuram, 516289, India; Asghar Z., Department of Mathematics and Sciences, College of Humanities and Sciences, Prince Sultan University, Riyadh, 11586, Saudi Arabia

A novel AI model for the extraction and prediction of Alzheimer disease from electronic health record
subject: Big data; Dark data; Electronic health record; Machine learning; Natural language processing
description: Dark data is an emerging concept, with its existence, identification, and utilization being key areas of research. This study examines various aspects and impacts of dark data in the healthcare domain and designs a model to extract essential clinical parameters for Alzheimer's from electronic health records (EHR). The novelty of dark data lies in its significant impact across sectors. In healthcare, even the smallest data points are crucial for diagnosis, prediction, and treatment. Thus, identifying and extracting dark data from medical data corpora enhances decision-making. In this research, a natural language processing (NLP) model is employed to extract clinical information related to Alzheimer's disease, and a machine learning algorithm is used for prediction. Named entity recognition (NER) with SpaCy is utilized to extract clinical departments from doctors' descriptions stored in EHRs. This NER model is trained on custom data containing processed EHR text and associated entity annotations. The extracted clinical departments can then be used for future Alzheimer's diagnosis via support vector machine (SVM) algorithms. Results show improved accuracy with the use of extracted dark data, highlighting its importance in predicting Alzheimer's disease. This research also explores the presence of dark data in various domains and proposes a dark data extraction model for the clinical domain using NLP. 2025 Institute of Advanced Engineering and Science. All rights reserved.
creator: Maju S.V.; Prakasi G.; Pushpam O.S.
source: Indonesian Journal of Electrical Engineering and Computer Science, Vol-37, No. 2, pp. 1023-1031.
publisher: Institute of Advanced Engineering and Science
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 25024752
format: Online
language: English
type: Article
coverage: Maju S.V., Department of Computer Science and Engineering, CHRIST University, Bengaluru, India; Prakasi G., Department of Computer Science and Engineering, CHRIST University, Bengaluru, India; Pushpam O.S., Department of Computer Science and Engineering, CHRIST University, Bengaluru, India

Internet chat based intervention as a mode for therapy and counselling
subject: chat-based intervention; college students; corporate employees; mental health; well-being
description: Increasing mental health issues in India demands for a strong intervention to curb the rise. According to the World Health Organization, roughly around 21 Indians out of 100,000 die by suicide every year. The burden on mental health domain increases due to the existing system as most of the existing services follow a traditional approach and are most sought after but lack reachability and ease of access. This study recognises the need for programmes that help in reachability and ease of access while simultaneously maintaining anonymity, therefore, analyses the impact of chat-based therapy provided online through the platform. The paper analyses the difference in subjective unit of well-being (SUW) pre and post chat-based sessions among 2624 college students and 805 corporate employees. The Wilcoxon signed rank test between pre and post intervention indicates significant results with the p < 0.001 (Z = -44.100a) suggesting and increase in SUW scores post intervention. Further, the Kruskal-Wallis test revealed that the gender of the clients has an association with the SUW scores (p < 0.05). It was also found that the duration of the sessions had a positive relation with the impact scores (p < 0.001). The Author(s), 2025.
creator: Gopinath J.K.; Rodrigues M.; Manuja P.
source: Global Mental Health, Vol-12
publisher: Cambridge University Press
date: 2025-01-01
rights: All Open Access; Gold Open Access
relation: ISSN: 20544251
format: Online
language: English
type: Article
coverage: Gopinath J.K., YourDost, Karnataka, Bangalore, India; Rodrigues M., Christ (Deemed to Be University), Karnataka, Bangalore, India; Manuja P., YourDost, Karnataka, Bangalore, India

Marketing odyssey for a digitally native brand: a case study of Sunbird Straws
subject: Advertising; Branding; Digital marketing; Digital marketing; Direct marketing; E-commerce; Global trend in marketing; Internet marketing; Return on ads spent (ROAS); Sustainable marketing; Sustainable straws
description: Research methodology: The case study incorporated a combination of primary and secondary data collection approach. The authors interviewed Dr Varghese, the co-founder of Sunbird Straws and the protagonist in this case study. In addition, secondary data was obtained from various sources such as newspaper articles, journal publications and company reports. Case overview/synopsis: On a rosy and vibrant morning in 2017, Dr Saji Varghese, a professor at Christ University in Bangalore, stumbled upon a curved coconut leaf on the campus resembling a straw. This sparked his motivation to transform coconut leaves into a natural straw, prompting him to initiate experiments with coconut leaves in his kitchen. The process of boiling and straining leaves became his method for crafting an eco-friendly straw. After numerous attempts, he successfully produced straws from coconut leaves, introducing a distinctive and creative concept incubated at IIM Bangalore. These unique straws, crafted by Varghese, prioritised environmental friendliness and were also crafted entirely from biodegradable materials, free from harmful chemicals. These straws demonstrated durability in hot and cold beverages for up to 3 h, maintaining their integrity without becoming soggy or leaking. As the business flourished, it reached a critical juncture. The primary challenge centred around product marketing, mainly due to consumer unfamiliarity with such sustainable straws. This was a product that also fell under the category of low involvement for consumers. Raising awareness about the product and persuading consumers to purchase presented a significant hurdle. In response, Varghese assigned his team to develop cost-effective marketing strategies. Given the start-up nature of the business, advertising budgets were constrained, and the objective was to achieve a positive return on advertising spend for every investment in advertising the product. In addition, the focus was on increasing the likelihood of sellin…
creator: Modi S.; Balaji V.; Datta P.; Singh Y.
source: CASE Journal, Vol-21, No. 1, pp. 159-186.
publisher: Emerald Publishing
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 15449106
format: Online
language: English
type: Article
coverage: Modi S., Department of School of Business and Management, Christ University, Bangalore, India; Balaji V., Department of School of Business and Management, Christ University, Bangalore, India; Datta P., Department of School of Business and Management, Christ University, Bangalore, India; Singh Y., Department of School of Business and Management, Christ University, Bangalore, India

TiO2-sodium alginate core-shell nanosystem for higher antimicrobial wound healing application
subject: Sodium alginate; Titanium dioxide; Wound healing
description: Wounds that are not properly managed can cause complications. Prompt and proper care is essential, to prevent microbial infection. Growing interest in metal oxide nanoparticles (NPs) for innovative wound treatments targeting healing and microbial infections. In this research, sodium alginate-coated titanium dioxide (TiSA) NPs are synthesized through a green co-precipitation method, combining inorganic TiO2 (Titanium dioxide) and SA (sodium alginate). Analysis via XRD and TEM revealed that the resulting TiSA NPs possessed an anatase phase and polygonal structure, respectively. Biomedical investigations demonstrated that TiSA NPs exhibited enhanced antimicrobial activity compared to the positive control, as well as its counterparts, and showed higher wound healing capabilities compared to TiO2 NPs. The antimicrobial effectiveness of TiSA NPs relied on various physicochemical factors, including small particle size, an altered band gap, and the presence of oxygen vacancies, resulting in microbial cell death. Moreover, TiSA NPs treatment demonstrated higher wound healing activity (98 1.09 %) compared to its counterparts after 24 h of incubation. Assessment of cytotoxicity on healthy fibroblast cells (L929) revealed that TiSA NPs exhibited lower toxicity compared to TiO2 NPs. These findings support the potential of TiSA NPs as promising agents for antimicrobial activity and wound healing. 2025 Elsevier B.V.
creator: Menon S.V.; Sandhwar V.; Chaudhary S.; Bhanot D.; Arulselvan P.; Govindasamy C.; Khan M.I.; Suriyaprakash J.; Thangavelu I.; Boopathi T.S.
source: International Journal of Biological Macromolecules, Vol-300
publisher: Elsevier B.V.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 1418130; PubMed ID: 39824397; CODEN: IJBMD
format: Online
language: English
type: Article
coverage: Menon S.V., Department of Chemistry and Biochemistry, JAIN (Deemed-to-be University), Karnataka, Bangalore, 560069, India; Sandhwar V., Department of Chemical Engineering, PIT, Parul University, Gujarat, Vadodara, 391760, India; Chaudhary S., Department of Sciences, Vivekananda Global University, Jaipur, 303012, India; Bhanot D., Centre of Research Impact and Outcome, Chitkara University, Punjab, Rajpura, 140417, India; Arulselvan P., Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Tamil Nadu, Chennai, 602 105, India; Govindasamy C., Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia; Khan M.I., Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia; Suriyaprakash J., Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006, China; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, 560029, India; Boopathi T.S., Department of Chemistry, Amrita School of Physical Sciences, Amrita Vishwa Vidyapeetham, Coimbatore, 641112, India, Functional Materials Laboratory, Amrita School of Engineering, Amrita Vishwa Vidyapeetham, Coimbatore, 641112, India

Patients trust in the Indian healthcare system and its impact on the intention to use artificial intelligence-based healthcare chatbots
subject: Chatbots; Complementary and alternative medicine; Distrust in health-care systems and doctors; Health care; Indian health seeking behaviour; Intention to use; Traditional; Trust in chatbots
description: Purpose: Indian patients have different medicine systems available at the service that alter their healthseeking behaviour (HSB). This study aims to examine the beliefs and behaviour of patients in India towards the healthcare system and how it affects their intention to use healthcare chatbots. Design/methodology/approach: A survey instrument was developed from standard scales and validated by experts. The data was collected from 397 respondents in an urban area and tested using a structural equation model in SAS JMP software. Findings: The study found that awareness and perception of chatbots and distrust on doctors and health systems impact trust in a chatbot. The results show that trust in chatbots influences the intention to use chatbots. The belief in alternative medicine systems and HSB also influence the intention to use chatbots. The study findings also imply that health-care chatbots should cater to HSB and the belief in alternative medicine. Research limitations/implications: The study was conducted only among the urban population because services based on technology are more available in metro cities. Bengaluru is considered the representative population of urban India. Practical implications: The level of disruption that chatbots can provide to the healthcare system makes this study significant. The study findings will help to manage the factors that can enable chatbot inclusivity, as the current system is inaccessible to many patients. Originality/value: This paper addresses an identified need to study patients trust in the Indian healthcare system and their intention to use chatbots. The level of disruptions these chatbots can cause in the health-care system is undeniable and patients trust in these chatbots will eventually transform the health-care sector. 2024, Emerald Publishing Limited.
creator: Chellasamy A.; N E.; Nagarathinam A.; Rangasamy S.
source: Journal of Asia Business Studies
publisher: Emerald Publishing
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 15587894
format: Online
language: English
type: Article
coverage: Chellasamy A., School of Business and Management, Christ University, Bangalore, India; N E., School of Business and Management, Christ University, Bangalore, India; Nagarathinam A., School of Business and Management, Christ University, Bangalore, India; Rangasamy S., School of Business and Management, Christ University, Bangalore, India

Structural and antibacterial assessment of two distinct dihydroxy biphenyls encapsulated with ?-cyclodextrin supramolecular complex
subject: Antibacterial activity; Gram-positive and gram-negative bacteria; Inclusion complex; Optical studies; Solid inclusion complex; ?-cyclodextrin
description: ?-Cyclodextrin plays a vital role in biological application because it can enhance the stability and solubility of the guest molecules in the supramolecular inclusion complexes. Moreover, the ?-Cyclodextrin inclusion complex has control-releasing behavior and lower toxicity than bare guest molecules. To improve the solubility and stability properties of two structurally different fluorescent guest molecules, namely 2,2?-dihydroxy biphenyl and 3,3?-dihydroxy biphenyls, they involve the ?-Cyclodextrin inclusion complex process. Optical measurements clearly described the efficient binding through the changes in the absorbance and emission intensities of guest molecules in the presence of ?-Cyclodextrin. The Job's plot from absorbance measurements reveals the 1:1 stochiometric ratio of binding of guests and the ?-Cyclodextrin host. The FT-IR spectra of the solid complex show the characteristic stretching and bending vibrations from both the guests and the host molecule. The 1HNMR spectra of the inclusion complex promote downfield shifting of guest molecule protons upon binding with the ?-Cyclodextrin host. The solid complex prepared using the solution method exhibits superior antibacterial activity against both gram-positive and gram-negative bacteria compared to the kneading and physical mixing methods. 2024
creator: Paramasivaganesh K.; Govindasamy C.; Shanmugasundaram E.; Krishnan N.K.; Saravanan C.; Thanusu J.; Thambusamy S.
source: Journal of Molecular Structure, Vol-1320
publisher: Elsevier B.V.
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 222860; CODEN: JMOSB
format: Online
language: English
type: Article
coverage: Paramasivaganesh K., Department of Industrial Chemistry, Alagappa University, Tamil Nadu, Karaikudi, 630003, India, Department of Chemistry, Arumugam Pillai Seethai Ammal College, Tamil Nadu, Tiruppattur, 630211, India; Govindasamy C., Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia; Shanmugasundaram E., Department of Industrial Chemistry, Alagappa University, Tamil Nadu, Karaikudi, 630003, India; Krishnan N.K., Department of Industrial Chemistry, Alagappa University, Tamil Nadu, Karaikudi, 630003, India; Saravanan C., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Thanusu J., Department of Chemistry, Alpha College of Engineering, Tamil Nadu, Chennai, 600124, India; Thambusamy S., Department of Industrial Chemistry, Alagappa University, Tamil Nadu, Karaikudi, 630003, India

PEGylated Platinum Nanoparticles: A Comprehensive Study of Their Analgesic and Anti-Inflammatory Effects
subject: Analgesic property; Anti-inflammatory Property; Cytotoxicity; DPPH assay; Platinum nanoparticles; Polyethylene glycol
description: Pain and inflammation are common symptoms of a majority of the diseases. Chronic pain and inflammation, as well as related dreadful disorders, remain difficult to control due to a lack of safe and effective medications. In this work, biocompatible platinum nanoparticles with significant analgesic and anti-inflammatory action were synthesized through a wet chemical method using polyethylene glycol-400 as a capping agent and sodium borohydride as a reducing agent. The average particle size of these Pt nanospheres was determined to be 3.26 nm using TEM analysis, and X-ray diffraction confirmed their face-centered cubic crystalline structure. Fourier transform infrared and UV-visible spectroscopy confirm that Pt-NPs are coated with the PEG-400 molecule. The significantly negative zeta potential value (?26.8 mV) indicates the stability of the produced nanoparticles. In vitro cytotoxicity studies on normal cell lines show nontoxic behavior with over 96% cell viability at 100 ?g/mL of the test sample. In vitro assays of inhibition of protein denaturation and DPPH free radical scavenging elucidated the anti-inflammatory and antioxidant properties of PEGylated Pt NPs with promising EC50 values 57.99 and 9.324 ?g/mL, respectively. In vivo animal trials confirmed that PEG-capped Pt-NPs are more effective than conventional medicines. The in vivo hot plate assay for the analgesic study shows a maximum response time of 14.5 1.22 s (92.54% analgesia) at a dosage of 50 mg/kg and 13.8 0.71 s (86.05% analgesia) at a dosage of 25 mg/kg after 180 and 240 min of administration, respectively. In the rat paw edema model for anti-inflammatory activity, the PEG-capped Pt NPs exhibit significant inhibitory action, with the maximum percentage of edema inhibition at a dosage of 50 mg/kg identical to that of the aspirin-based standard medication administered at a higher dosage of 100 mg/kg, resulting in 42% inhibition, suggesting a versatile solution for inflammation and persistent pain. 2025 A…
creator: Waliaveettil F.A.; Jose J.; Anila E.I.
source: ACS Applied Bio Materials, Vol-8, No. 1, pp. 628-641.
publisher: American Chemical Society
date: 2025-01-01
rights: Restricted Access
relation: ISSN: 25766422; PubMed ID: 39746938
format: Online
language: English
type: Article
coverage: Waliaveettil F.A., Department of Physics and Electronics, Christ University, Karnataka, Bengaluru, 560029, India; Jose J., Division of Microbiology, Department of Biosciences, Rajagiri College of Social Sciences (Autonomous), Kerala, Cochin, 683104, India; Anila E.I., Department of Physics and Electronics, Christ University, Karnataka, Bengaluru, 560029, India