HMOSHSSA: a novel framework for solving simultaneous clustering and feature selection problems
Dimensionality reduction; Feature selection; Partitional clustering; Pattern recognition; Salp swarm algorithm; Spotted hyena optimizer
In real-life scenarios, information about the number of clusters is unknown. Due to this, clustering algorithms are unable to generate the valuable partitions. Beside this, the appropriate and optimal number of features is also required to produce the good quality clusters. The selection of optimal number of clusters and feature is a challenging task in the clustering. To resolve these problems, an automatic multi-objective-based clustering approach called HMOSHSSA is proposed in this paper. In HMOSHSSA, the spotted hyena and salp swarm algorithms are hybridized to obtain a better trade-off between these algorithms intensification and diversification capabilities. Two novel concepts for encoding and threshold setting are incorporated in the HMOSHSSA. The encoding scheme is used to choose the optimal number of clusters and features during the optimization process. The variance of dataset is used for setting the threshold values for both clusters and features. A novel fitness function is proposed to improve the optimization process. The suggested algorithms performance is evaluated using eight well-known real-world datasets. The statistical significance of HMOSHSSA is measured through t-tests. Results reveal that the proposed approach is able to detect the optimal number of clusters and features from a given dataset without user intervention. This approach is also deployed for solving microarray data analysis and image segmentation problems. HMOSHSSA outperformed the other considered algorithms in terms of performance measures. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.
Multimedia Tools and Applications, Vol-83, No. 35, pp. 82149-82175.
Kumar V., Department of Information Technology, Dr. B.R. Ambedkar National Institute of Technology Jalandhar, Punjab, 147008, India; Kumari R., ICFAI Business School (IBS) Bangalore, Off-Campus Center of ICFAI Foundation for Higher Education (IFHE) University, Bangalore, India; Kumar S., Department of Computer Science and Engineering, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560074, India
A critical assessment of technical advances in pharmaceutical removal from wastewater A critical review
Ecological toxicity; Pharmaceutical metabolites; Removal technologies; Wastewater treatment
Use of pharmaceutical products has seen a tremendous increase in the recent decades. It has been observed that more than thirty million tons of pharmaceuticals are consumed worldwide. The used pharmaceutical products are not completely metabolized in human and animal body. Therefore, they are excreted to the environment and remain there as persistent organic chemicals. These compounds emerge as toxic contaminants in water and affect the human metabolism directly or indirectly. This literature review is an endeavour to understand the origin, applications and current advancement in the removal of pharmaceuticals from the environment. It discusses about the pharmaceuticals used in medical applications such diagnosis and disease treatment. In addition, it discusses about the recent approaches applied in pharmaceutical removal including microbial fuel cells, biofiltration, and bio nanotechnology approaches. Moreover, the challenges associated with pharmaceutical removal are presented considering biological and environmental factors. The review suggest the potential recommendations on pharmaceutical removal. 2023 The Authors
Kumar V.; Lakkaboyana S.K.; Sharma N.; Chakraborty P.; Umesh M.; Pasrija R.; Thomas J.; Kalebar V.U.; Jayaraj I.; Awasthi M.K.; Das T.; Oladipo A.A.; Barcelo D.; Dumee L.F.
Case Studies in Chemical and Environmental Engineering, Vol-8
All Open Access; Gold Open Access; Green Open Access
https://doi.org/10.1016/j.cscee.2023.100363 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85160539976&doi=10.1016%2fj.cscee.2023.100363&partnerID=40&md5=96edf02d7b7c7fba36d00316900cf020
Kumar V., Ecotoxicity and Bioconversion Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, 602105, India; Lakkaboyana S.K., Department of Chemistry, Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology, Avadi, Chennai, 600062, India; Sharma N., Metagenomics and Bioprocess Design Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, India; Chakraborty P., School of Allied Healthcare and Sciences, Jain (Deemed to be) University, Whitefield, Bangalore, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), HosurRoad, Karnataka, Bengaluru, 560029, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Thomas J., Department of Biotechnology, Mar Athanasius College, Kerala, India; Kalebar V.U., Department of Molecular Medicine, School of Allied Health Care and Sciences, Jain (Deemed to be) University, Bangalore, India; Jayaraj I., Department of Biotechnology, Saveetha School of Engineering, SIMATS, Thandalam, Chennai, 602105, India; Awasthi M.K., College of Natural Resources and Environment, Northwest A&F University, Yangling, 712100, China; Das T., Infection, Immunity and Inflammation, Charles Perkins Centre, Sydney Institute for Infectious Diseases, School of Medical Sciences, The University of Sydney, Sydney, 2006, NSW, Australia; Oladipo A.A., Polymeric Materials Research Laboratory, Department of Chemistry, Faculty of Arts and Sciences, Eastern Mediterranean University, Famagusta TR North Cyprus, via Mersin 10, Turkey; Barcelo D., Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research, IDAEA-CSIC, Jordi Girona, 18-26, Barcelona, 08034, Spain, Sustainability Cluster, School of Engineering, UPES, Dehradun, India; Dumee L.F., Department of Chemical Engineering, Khalifa University, Abu Dhabi, United Arab Emirates
Commercialization potential of agro-based polyhydroxyalkanoates biorefinery: A technical perspective on advances and critical barriers
Agro waste bioconversion; Polyhydroxyalkanoates commercialization; Polyhydroxyalkanoates production; Waste utilization
The exponential increase in the use and careless discard of synthetic plastics has created an alarming concern over the environmental health due to the detrimental effects of petroleum based synthetic polymeric compounds. Piling up of these plastic commodities on various ecological niches and entry of their fragmented parts into soil and water has clearly affected the quality of these ecosystems in the past few decades. Among the many constructive strategies developed to tackle this global issue, use of biopolymers like polyhydroxyalkanoates as sustainable alternatives for synthetic plastics has gained momentum. Despite their excellent material properties and significant biodegradability, polyhydroxyalkanoates still fails to compete with their synthetic counterparts majorly due to the high cost associated with their production and purification thereby limiting their commercialization. Usage of renewable feedstocks as substrates for polyhydroxyalkanoates production has been the thrust area of research to attain the sustainability tag. This review work attempts to provide insights about the recent developments in the production of polyhydroxyalkanoates using renewable feedstock along with various pretreatment methods used for substrate preparation for polyhydroxyalkanoates production. Further, the application of blends based on polyhydroxyalkanoates, and the challenges associated with the waste valorization based polyhydroxyalkanoates production strategy is elaborated in this review work. 2023 Elsevier B.V.
Kumar V.; Lakkaboyana S.K.; Tsouko E.; Maina S.; Pandey M.; Umesh M.; Singhal B.; Sharma N.; Awasthi M.K.; Andler R.; Jayaraj I.; Yuzir A.
International Journal of Biological Macromolecules, Vol-234
ISSN: 1418130; PubMed ID: 36801274; CODEN: IJBMD
https://doi.org/10.1016/j.ijbiomac.2023.123733 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85148364620&doi=10.1016%2fj.ijbiomac.2023.123733&partnerID=40&md5=92bc14415d03c9d18977806ac12fd109
Kumar V., Ecotoxicity and Bioconversion Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India, Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Uttarakhand, Roorkee, India; Lakkaboyana S.K., Department of Chemistry, Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology, Avadi, Chennai, 600062, India, Department of Chemical and Environmental Engineering (ChEE), Malaysia-Japan International Institute of Technology (MJIIT)-Universiti Technologi Malaysia, Jalan Sultan Yahya Petra, Kuala Lumpur, 54100, Malaysia; Tsouko E., Department of Food Science and Nutrition, School of Environment, University of the Aegean, Metropolite Ioakeim 2, Lemnos, Myrina, 81400, Greece; Maina S., Department of Food Science and Human Nutrition, Agricultural University of Athens, Iera Odos 75, Athens, 11855, Greece; Pandey M., School of Biotechnology, Gautam Buddha University, U.P., Greater Noida, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560029, India; Singhal B., School of Biotechnology, Gautam Buddha University, U.P., Greater Noida, India; Sharma N., Metagenomics and Bioprocess Design Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, India; Awasthi M.K., College of Natural Resources and Environment, Northwest A&F University, Yangling, 712100, China; Andler R., Escuela de Ingenier en Biotecnolog, Centro de Biotecnolog de los Recursos Naturales (Cenbio), Universidad Catica del Maule, Chile; Jayaraj I., Department of Bioengineering, Institute of Biotechnology, Saveetha School of Engineering, SIMATS, Chennai, 602105, India; Yuzir A., Department of Chemical and Environmental Engineering (ChEE), Malaysia-Japan International Institute of Technology (MJIIT)-Universiti Technologi Malaysia, Jalan Sultan Yahya Petra, Kuala Lumpur, 54100, Malaysia
Design considerations of an inductive sensor for segmented mirror telescopes
Astronomy; Edge Sensor; Mutual inductance; Planar inductor; Primary mirror control system; Segmented mirror telescope
The Segmented mirror technology has become natural choice for any optical telescope larger than 8 meter in size, where small mirror segments are aligned and positioned with respect to each other to an accuracy of few tens of nanometer. Primary mirror control system with the help of edge sensor and soft linear actuator maintains that alignment which changes due to gravity and wind loading. For any segmented mirror telescope edge-sensor plays very critical role. It should have very high spatial resolution (few nanometer), large range, multidimensional sensing, high temporal stability as well as immunity towards relative change in temperature and humidity. Though capacitive sensors are widely used for this purpose, however, their inherent sensitivity towards humidity and dust make them unsuitable for telescopes operating at humid low altitude regions. Whereas, inductance based sensors, working on the principal of mutual inductance variation between two planar inductor coils, produce promising results in such a situation. Looking at stringent requirements, design and development of a planar inductive sensor is a challenge. As a first step toward sensor development, we have explored the design aspects of it. The inductive coils are first simulated and analyzed using electromagnetic FEA software for different coil parameters. The design considerations include optimization of coil parameters such as geometry of coils, trace densities, number of turns, etc. and operational requirements such as number of degree of freedoms to be sensed, range of travel, spatial resolution, as well as required sensitivity. The simulation results are also verified through experimentation. In this first paper we report the design and analysis results obtained from FEA simulations. 2018 SPIE.
Kumar V.; Parihar P.; Nakulan A.; Manoharan A.
Proceedings of SPIE - The International Society for Optical Engineering, Vol-10700
https://doi.org/10.1117/12.2313009 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85051262452&doi=10.1117%2f12.2313009&partnerID=40&md5=2e0c7268e43c0ae21d6914fac8aaa615
Kumar V., Indian Institute of Astrophysics, Koramangala 2nd Block, Bengaluru, Karnataka, 560034, India; Parihar P., Indian Institute of Astrophysics, Koramangala 2nd Block, Bengaluru, Karnataka, 560034, India; Nakulan A., Christ University, Bhavani Nagar, Bengaluru, Karnataka, 560029, India; Manoharan A., Christ University, Bhavani Nagar, Bengaluru, Karnataka, 560029, India
Environmental Pollutants as Emerging Concerns for Cardiac Diseases: A Review on Their Impacts on Cardiac Health
cardiac health; cardiovascular diseases (CVDs); environmental pollutants; health risk factors; particulate matter
Comorbidities related to cardiovascular disease (CVD) and environmental pollution have emerged as serious concerns. The exposome concept underscores the cumulative impact of environmental factors, including climate change, air pollution, chemicals like PFAS, and heavy metals, on cardiovascular health. Chronic exposure to these pollutants contributes to inflammation, oxidative stress, and endothelial dysfunction, further exacerbating the global burden of CVDs. Specifically, carbon monoxide (CO), ozone, particulate matter (PM2.5), nitrogen dioxide (NO2), sulfur dioxide (SO2), heavy metals, pesticides, and micro- and nanoplastics have been implicated in cardiovascular morbidity and mortality through various mechanisms. PM2.5 exposure leads to inflammation and metabolic disruptions. Ozone and CO exposure induce oxidative stress and vascular dysfunction. NO2 exposure contributes to cardiac remodeling and acute cardiovascular events, and sulfur dioxide and heavy metals exacerbate oxidative stress and cellular damage. Pesticides and microplastics pose emerging risks linked to inflammation and cardiovascular tissue damage. Monitoring and risk assessment play a crucial role in identifying vulnerable populations and assessing pollutant impacts, considering factors like age, gender, socioeconomic status, and lifestyle disorders. This review explores the impact of cardiovascular disease, discussing risk-assessment methods, intervention strategies, and the challenges clinicians face in addressing pollutant-induced cardiovascular diseases. It calls for stronger regulatory policies, public health interventions, and green urban planning. 2025 by the authors.
Kumar V.; S H.; Huligowda L.K.D.; Umesh M.; Chakraborty P.; Thazeem B.; Singh A.P.
Multidisciplinary Digital Publishing Institute (MDPI)
https://doi.org/10.3390/biomedicines13010241 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85215696363&doi=10.3390%2fbiomedicines13010241&partnerID=40&md5=4af2b6c670183c68f0ab2ea7db9401ae
Kumar V., Biomaterials & Tissue Engineering (BITE) Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, SIMATS, Chennai, Tamil Nadu, Thandalam, 602105, India; S H., Biomaterials & Tissue Engineering (BITE) Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, SIMATS, Chennai, Tamil Nadu, Thandalam, 602105, India; Huligowda L.K.D., Institute for Water and Wastewater Technology, Durban University of Technology, Durban, 4001, South Africa; Umesh M., Department of Life Sciences, Christ University, Hosur Road, Karnataka, Bengaluru, 560029, India; Chakraborty P., Area of Molecular Medicine, Department of Allied Healthcare and Sciences, JAIN (Deemed to be University), Karnataka, Bangalore, 560066, India; Thazeem B., Waste Management Division, Integrated Rural Technology Centre (IRTC), Kerala, Palakkad, 678592, India; Singh A.P., Frankel Cardiovascular Center, Department of Medicine, University of Michigan, Ann Arbor, 48109, MI, United States
Microbial engineering strategies for synthetic microplastics clean up: A review on recent approaches
Biotechnology approaches; Enzyme engineering; Microbial engineering; Microplastic; Microplastic removal; Sources of microplastics
Microplastics are the small fragments of the plastic molecules which find their applications in various routine products such as beauty products. Later, it was realized that it has several toxic effects on marine and terrestrial organisms. This review is an approach in understanding the microplastics, their origin, dispersal in the aquatic system, their biodegradation and factors affecting biodegradation. In addition, the paper discusses the major engineering approaches applied in microbial biotechnology. Specifically, it reviews microbial genetic engineering, such as PET-ase engineering, MHET-ase engineering, and immobilization approaches. Moreover, the major challenges associated with the plastic removal are presented by evaluating the recent reports available. 2022 Elsevier B.V.
Kumar V.; Sharma N.; Duhan L.; Pasrija R.; Thomas J.; Umesh M.; Lakkaboyana S.K.; Andler R.; Vangnai A.S.; Vithanage M.; Awasthi M.K.; Chia W.Y.; LokeShow P.; BarcelD.
Environmental Toxicology and Pharmacology, Vol-98
ISSN: 13826689; PubMed ID: 36572198; CODEN: ETOPF
https://doi.org/10.1016/j.etap.2022.104045 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85145330547&doi=10.1016%2fj.etap.2022.104045&partnerID=40&md5=787d0a39baf8361db79199522d672d04
Kumar V., Department of Community Medicine, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India, Ecotoxicity and Bioconversion Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Thandalam, 602105, India; Sharma N., School of Biotechnology, Jawaharlal Nehru University, New Delhi, India; Duhan L., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Thomas J., Department of Biotechnology, Mar Athanasius College, Kerala, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Lakkaboyana S.K., Department of Chemistry, Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology, Avadi, Chennai, 600062, India; Andler R., Escuela de Ingenier en Biotecnolog, Centro de Biotecnolog de los Recursos Naturales (Cenbio), Universidad Catica del Maule, Chile; Vangnai A.S., Center of Excellence in Biocatalyst and Sustainable Biotechnology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand; Vithanage M., Ecosphere Resilience Research Center, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda, 10250, Sri Lanka; Awasthi M.K., College of Natural Resources and Environment, Northwest A&F University, Yangling, 712100, China; Chia W.Y., Department of Chemical and Environmental Engineering, Faculty Science and Engineering, University of Nottingham, Selangor Darul Ehsan, Semenyih, 43500, Malaysia; LokeShow P., Department of Chemical and Environmental Engineering, Faculty Science and Engineering, University of Nottingham, Selangor Darul Ehsan, Semenyih, 43500, Malaysia, Zhejiang Provincial Key Laboratory for Subtropical Water Environment and Marine Biological Resources Protection, Wenzhou University, Wenzhou, 325035, China, Department of Sustainable Engineering, Saveetha School of Engineering, SIMATS, Chennai, 602105, India; BarcelD., Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research, IDAEA-CSIC, Jordi Girona, 1826, Barcelona, 08034, Spain, Catalan Institute for Water Research (ICRA-CERCA), Parc Cientic i Tecnolic de la Universitat de Girona, c/Emili Grahit, 101, Edifici H2O, Girona, 17003, Spain, Sustainability Cluster, School of Engineering, UPES, Dehradun, India
Synthesis and characterization of chitosan nanofibers for wound healing and drug delivery application
Chitosan nanofibers; Drug delivery; Nanofibers modifications; Nanofibers synthesis; Wound healing
Chitosan has emerged as a biodegradable, absorbable, non-toxic, biocompatible biopolymer for wound healing and drug delivery applications. Chitosan can be converted to nanofibers which have higher potential for wound healing and drug delivery applications as compared to chitosan nanoparticles and nanocomposites. Due to these properties chitosan nanofiber has emerged as a promising candidate for biomedical research. In the recent decades it has been observed that several studies reported about the production and medical applications of chitosan nanofibers. Although, preparation and application of chitosan nanofibers is easy. But there are several challenges and bottlenecks associated with its practical application and large-scale production. The presented review is a comprehensive discussion on the major challenges and bottlenecks associated with chitosan nanofibers synthesis and their practical applications in biomedical research. It discusses critically about the issues related to the chitosan nanofibers solubility, stability, mechanical strength, absorption and drug release properties, and its scale up hinderances. Moreover, the review presents an insight into the future recommendations on considering the parameters associated for development of an efficient, sustainable, and promising biopolymer. 2023 Elsevier B.V.
Kumar V.; Sharma N.; Janghu P.; Pasrija R.; Umesh M.; Chakraborty P.; Sarojini S.; Thomas J.
Journal of Drug Delivery Science and Technology, Vol-87
https://doi.org/10.1016/j.jddst.2023.104858 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85170292007&doi=10.1016%2fj.jddst.2023.104858&partnerID=40&md5=19d648d71b96f83d40d7dbbf42a50082
Kumar V., Bioconversion and Tissue Engineering Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India; Sharma N., Metagenomics and Bioprocess Design Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, India; Janghu P., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Chakraborty P., School of Allied Healthcare and Sciences, Jain (Deemed to be) University, Whitefield, Karnataka, Bangalore, 560066, India; Sarojini S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Thomas J., Department of Biotechnology, Mar Athanasius College, Kerala, India
Lignocellulosic biomass for biochar production: A green initiative on biowaste conversion for pharmaceutical and other emerging pollutant removal
Biochar; Biowaste; Functionalization; Lignocellulose; Nano adsorbents; Wastewater treatment
Lignocellulosic waste generation and their improper disposal has accelerated the problems associated with increased greenhouse gas emissions and associated environmental pollution. Constructive ways to manage and mitigate the pollution associated with lignocellulosic waste has propelled the research on biochar production using lignocellulose-based substrates. The sustainability of various biochar production technologies in employing lignocellulosic biomass as feedstock for biochar production not only aids in the lignocellulosic biomass valorization but also helps in carbon neutralization and carbon utilization. Functionalization of biochar through various physicochemical methods helps in improving their functional properties majorly by reducing the size of the biochar particles to nanoscale and modifying their surface properties. The usage of engineered biochar as nano adsorbents for environmental applications like dye absorption, removal of organic pollutants and endocrine disrupting compounds from wastewater has been the thrust areas of research in the past few decades. This review presents a comprehensive outlook on the up-to-date research findings related to the production and engineering of biochar from lignocellulosic biomass and their applications in environmental remediation especially with respect to wastewater treatment. Further a detailed discussion on various biochar activation methods and the future scope of biochar research is presented in this review work. 2024 Elsevier Ltd
Kumar V.; Sharma N.; Panneerselvam B.; Dasarahally Huligowda L.K.; Umesh M.; Gupta M.; Muzammil K.; Zahrani Y.; Malmutheibi M.
ISSN: 456535; PubMed ID: 38761824; CODEN: CMSHA
https://doi.org/10.1016/j.chemosphere.2024.142312 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85193780264&doi=10.1016%2fj.chemosphere.2024.142312&partnerID=40&md5=e2f4080f81783b196456c85ce1a23d33
Kumar V., Biomaterials and Tissue Engineering (BITE) Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India; Sharma N., Department of Biochemistry, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India; Panneerselvam B., Center of Excellence in Interdisciplinary Research for Sustainable Development, Chulalongkorn University, Bangkok, 10330, Thailand, Department of Community Medicine, Saveetha Medical College, SIMATS, Chennai, 602105, India; Dasarahally Huligowda L.K., Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Uttarakhand, Roorkee, 247667, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Gupta M., Chitkara Centre for Research and Development, Chitkara University, Himachal Pradesh, 174103, India; Muzammil K., Department of Public Health, College of Applied Medical Sciences, Khamis Mushait Campus, King Khalid University, Abha, 62561, Saudi Arabia; Zahrani Y., Department of Public Health, College of Applied Medical Sciences, Khamis Mushait Campus, King Khalid University, Abha, 62561, Saudi Arabia; Malmutheibi M., Department of Public Health, College of Applied Medical Sciences, Khamis Mushait Campus, King Khalid University, Abha, 62561, Saudi Arabia
Toxicity analysis of endocrine disrupting pesticides on non-target organisms: A critical analysis on toxicity mechanisms
Biochemical mechanisms; Endocrine disruptors; Genotoxicity; Neurotoxicity; Non-target toxicity
Endocrine disrupting compounds are the chemicals which mimics the natural endocrine hormones and bind to the receptors made for the hormones. Upon binding they activate the cascade of reaction which leads to permanent activating of the signalling cycle and ultimately leads to uncontrolled growth. Pesticides are one of the endocrine disrupting chemicals which cause cancer, congenital birth defects, and reproductive defects in non-target organisms. Non-target organisms are keen on exposing to these pesticides. Although several studies have reported about the pesticide toxicity. But a critical analysis of pesticide toxicity and its role as endocrine disruptor is lacking. Therefore, the presented review literature is an endeavour to understand the role of the pesticides as endocrine disruptors. In addition, it discusses about the endocrine disruption, neurological disruption, genotoxicity, and ROS induced pesticide toxicity. Moreover, biochemical mechanisms of pesticide toxicity on non-target organisms have been presented. An insight on the chlorpyrifos toxicity on non-target organisms along with species names have been presented. 2023 Elsevier Inc.
Kumar V.; Sharma N.; Sharma P.; Pasrija R.; Kaur K.; Umesh M.; Thazeem B.
Toxicology and Applied Pharmacology, Vol-474
https://doi.org/10.1016/j.taap.2023.116623 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85165085943&doi=10.1016%2fj.taap.2023.116623&partnerID=40&md5=d4d16d8fa2daf6cc0567f3e74ca0adc7
Kumar V., Bioconversion and Tissue Engineering Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India; Sharma N., Metagenomics and Bioprocess Design Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, India; Sharma P., Department of Biochemistry, Maharshi Dayanand University, Haryana, Rohtak, 124001, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Haryana, Rohtak, 124001, India; Kaur K., Punjab Agricultural University, Institute of Agriculture, Gurdaspur, 143521, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Thazeem B., Waste Management Division, Integrated Rural Technology Centre (IRTC), Kerala, Palakkad, 678592, India
Micropollutants characteristics, fate, and sustainable removal technologies for landfill leachate: A technical perspective
Advanced treatment; Bioremediation; Landfill leachate; Micropollutants; Pesticides
Waste disposal in landfills has gained momentum in the last few decades as it is one among the easy and cost-effective method for waste management for the accelerating global population. Heterogenous nature of the waste ending up in landfills makes it difficult to predict the fate of these pollutants making it difficult for its biomonitoring and specific treatment. Among the major issues associated with landfill treatment, liquid percolation from this heterogenous waste substrate collectively referred as leachate poses the greater risk to environment through soil and ground water pollution. The diversity of micropollutants presents in landfill leachates ranging from microbial pathogens, pesticides, microplastics, pharmaceuticals and other harmful chemicals calls for crucial attention towards improving methods used for their treatment and removal. This review summarizes the key components of landfill leachates with specific emphasize on micropollutant content of leachate. Further the features of most recent and advanced technologies that were successfully explored for micropollutant removal from landfill leachates are presented in this review. 2023 Elsevier Ltd
Kumar V.; Sharma N.; Umesh M.; Chakraborty P.; Kaur K.; Duhan L.; Sarojini S.; Thazeem B.; Pasrija R.; Vangnai A.S.; Maitra S.S.
Journal of Water Process Engineering, Vol-53
https://doi.org/10.1016/j.jwpe.2023.103649 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85150059158&doi=10.1016%2fj.jwpe.2023.103649&partnerID=40&md5=249d4a85736a8f37037afe0d399b4795
Kumar V., Ecotoxicity and Bioconversion Laboratory, Department of Community Medicine, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India; Sharma N., Metagenomics and Bioprocess Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Chakraborty P., School of Allied Healthcare and Sciences, Jain (Deemed to be) University, Whitefield, Karnataka, Bangalore, 66, India; Kaur K., Department of Chemistry, Punjab Agricultural University, Punjab, Ludhiana, 141004, India; Duhan L., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Sarojini S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Thazeem B., Integrated Rural Technology Centre (IRTC), Mundur, Palakkad, 678592, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Vangnai A.S., Center of Excellence in Biocatalyst and Sustainable Biotechnology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand; Maitra S.S., Metagenomics and Bioprocess Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, India
Microplastics in food: Occurrence, toxicity, green analytical detection methods and future challenges
Environmental pollutants; Food contamination; Green analytical methods; MPs; Toxicity
The pervasive presence of microplastics (MPs) in the environment has raised significant concerns about their infiltration into the human food chain. In current review, the occurrence and distribution of MPs in various food matrices such as seafood, drinking water, fruits, vegetables, and beverages are discussed along with their potential routes of MPs entry into the human food chain. The toxicity of MPs on human health and different organs are discussed in brief. Current technological advancement and green analytical methods for the detection of MPs in food samples are compared, discussing their advantages and limitations. Green analytical methods, including stereomicroscopy, Fourier Transform Infrared spectroscopy, Raman spectroscopy, and enzymatic digestion, are evaluated for their efficacy and environmental impact. The Analytical Eco-Scale is used to assess the greenness of these methods. Challenges associated with MPs detection in food, such as complex food matrices, pretreatment methods, and variability in MPs concentrations, are addressed. 2024 The Author(s)
Kumar V.; Sharma N.; Umesh M.; Gupta P.; Sharma P.; Basheer T.; Huligowda L.K.D.; Thomas J.; Bhagat S.K.; Pasrija R.
https://doi.org/10.1016/j.greeac.2024.100152 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85203658566&doi=10.1016%2fj.greeac.2024.100152&partnerID=40&md5=5b1a3bf5d893babc5cb44dea8d1e56ee
Kumar V., Biomaterials & Tissue Engineering (BITE) Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India; Sharma N., Department of Biochemistry, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Gupta P., Department of Biotechnology, Graphic Era Deemed to be University, Uttarakhand, Dehradun, 248001, India; Sharma P., Department of Biochemistry, Maharshi Dayanand University, Haryana, Rohtak, 124001, India; Basheer T., Waste Management Division, Integrated Rural Technology Centre (IRTC), Kerala, Palakkad, 678592, India; Huligowda L.K.D., Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Uttarakhand, Roorkee, 247667, India; Thomas J., Department of Biotechnology, Mar Athanasius College, Kerala, India; Bhagat S.K., Marwadi University Research Center, Department of Civil Engineering, Faculty of Engineering & Technology, Marwadi University, Gujarat, Rajkot, 360003, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Haryana, Rohtak, 124001, India
Emerging challenges for the agro-industrial food waste utilization: A review on food waste biorefinery
Agro-industrial waste; Challenges in biorefinery; Fermentable sugars; Food biorefinery; Food waste technologies
Modernization and industrialization has undoubtedly revolutionized the food and agro-industrial sector leading to the drastic increase in their productivity and marketing thereby accelerating the amount of agro-industrial food waste generated. In the past few decades the potential of these agro-industrial food waste to serve as bio refineries for the extraction of commercially viable products like organic acids, biochemical and biofuels was largely discussed and explored over the conventional method of disposing in landfills. The sustainable development of such strategies largely depends on understanding the techno economic challenges and planning for future strategies to overcome these hurdles. This review work presents a comprehensive outlook on the complex nature of agro-industrial food waste and pretreatment methods for their valorization into commercially viable products along with the challenges in the commercialization of food waste bio refineries that need critical attention to popularize the concept of circular bio economy. 2022
Kumar V.; Sharma N.; Umesh M.; Selvaraj M.; Al-Shehri B.M.; Chakraborty P.; Duhan L.; Sharma S.; Pasrija R.; Awasthi M.K.; Lakkaboyana S.R.; Andler R.; Bhatnagar A.; Maitra S.S.
ISSN: 9608524; PubMed ID: 35973569; CODEN: BIRTE
https://doi.org/10.1016/j.biortech.2022.127790 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85136107133&doi=10.1016%2fj.biortech.2022.127790&partnerID=40&md5=20d71d666c81453d2eccd344482a8dd6
Kumar V., Department of Community Medicine, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Chennai, India; Sharma N., School of Biotechnology, Jawaharlal Nehru University, New Delhi, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Selvaraj M., Department of Chemistry, Faculty of Science, King Khalid University, Abha, 61413, Saudi Arabia, Research Center for Advanced Materials Science (RCAMS), King Khalid University, P.O. Box 9004, Abha, 61413, Saudi Arabia; Al-Shehri B.M., Department of Chemistry, Faculty of Science, King Khalid University, Abha, 61413, Saudi Arabia, Research Center for Advanced Materials Science (RCAMS), King Khalid University, P.O. Box 9004, Abha, 61413, Saudi Arabia, Unit of Bee Research and Honey Production, Faculty of Science, King Khalid University, P.O. Box 9004, Abha, 61413, Saudi Arabia; Chakraborty P., School of Allied Healthcare and Sciences, Jain (Deemed To Be) University, Karnataka, Bengaluru, India; Duhan L., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Sharma S., Department of Chemistry, College of Basic Sciences and Humanities, Punjab Agricultural University, Punjab, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Awasthi M.K., College of Natural Resources and Environment, Northwest A&F University, Yangling, 712100, China; Lakkaboyana S.R., Department of Chemistry, Vel Tech Rangarajan Dr, Sagunthala R&D Institute of Science and Technology, Chennai, Avadi, 600062, India; Andler R., Escuela de Ingenier en Biotecnolog, Centro de Biotecnolog de los Recursos Naturales (Cenbio), Universidad Catica del Maule; Bhatnagar A., Department of Separation Science, LUT School of Engineering Science, LUT University, Sammonkatu 12, Mikkeli, FI-50130, Finland; Maitra S.S., School of Biotechnology, Jawaharlal Nehru University, New Delhi, India
Commercialization potential of PET (polyethylene terephthalate) recycled nanomaterials: A review on validation parameters
Circular economy; Growth drivers; Nanomaterials; PET commercialization; Safety considerations; Scale-up and manufacturing challenges
Polyethylene Terephthalate (PET) is a polymer which is considered as one of the major contaminants to the environment. The PET waste materials can be recycled to produce value-added products. PET can be converted to nanoparticles, nanofibers, nanocomposites, and nano coatings. To extend the applications of PET nanomaterials, understanding its commercialization potential is important. In addition, knowledge about the factors affecting recycling of PET based nanomaterials is essential. The presented review is focused on understanding the PET commercialization aspects, keeping in mind market analysis, growth drivers, regulatory affairs, safety considerations, issues associated with scale-up, manufacturing challenges, economic viability, and cost-effectiveness. In addition, the paper elaborates the challenges associated with the use of PET based nanomaterials. These challenges include PET contamination to water, soil, sediments, and human exposure to PET nanomaterials. Moreover, the paper discusses in detail about the factors affecting PET recycling, commercialization, and circular economy with specific emphasis on life cycle assessment (LCA) of PET recycled nanomaterials. 2024 Elsevier Ltd
Kumar V.; Sharma N.; Umesh M.; Sharma R.; Sharma M.; Sharma D.; Sondhi S.; Thomas J.; Kumar D.; Kansal L.; Jha N.K.
https://doi.org/10.1016/j.chemosphere.2024.141453 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85185530914&doi=10.1016%2fj.chemosphere.2024.141453&partnerID=40&md5=81adf45e13c88b11e90f410589c98017
Kumar V., Bioconversion and Tissue Engineering (BITE) Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Thandalam, 602105, India; Sharma N., Department of Biochemistry, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Thandalam, 602105, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Sharma R., Department of Biotechnology, Chandigarh College of Technology, Chandigarh Group of Colleges, Landran, Punjab, Mohali, 140307, India; Sharma M., Department of Plant Sciences, Central University of Himachal Pradesh, Shahpur Campus, Himachal Pradesh, Kangra, 176206, India; Sharma D., Department of Biotechnology, Chandigarh College of Technology, Chandigarh Group of Colleges, Landran, Punjab, Mohali, 140307, India; Sondhi S., Haryana State Pollution Control Board, C-11, Haryana, Panchkula, India; Thomas J., Department of Biotechnology, Mar Athanasius College, Kerala, India; Kumar D., Department of Biotechnology-UIBT, Chandigarh University, Punjab, India; Kansal L., School of Electronics and Electrical Engineering, Lovely Professional University, Phagwara, India; Jha N.K., Centre for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India, Centre for Research Impact and Outcomes, Chitkara University, Punjab, Rajpura, India, Department of Biotechnology, School of Applied & Life Sciences (SALS), Uttaranchal University, Dehradun, 248007, India
Origin, ecotoxicity, and analytical methods for microplastic detection in aquatic systems
Analytical methods; Aquatic ecosystem; Challenges and bottlenecks; Characterization; Microplastics; Toxicity
Over the decades, interaction of microplastics with other pollutants in a dynamic environmental set up was observed to increase their toxic effects. This scenario is worse in aquatic environments due to the entry of huge loads of microplastic components into the waterbodies through direct plastic dumping and those delivered from effluents originating from various treatment plants. Although extensive research was done to understand the issue associated with microplastic contamination of various aquatic environments, a huge research gap still exists in areas like their ecotoxicology, fate, distribution, and detection methods in aquatic environments. Moreover, the combined deleterious effect of microplastics in association with other environmental pollutants is not widely studied and requires more research focus. The major scope of this review is to present a comprehensive outlook on the recent studies carried out to understand the types, origin, distribution, transport, fate, and toxicity of microplastics in aquatic environments, both fresh water and marine. The review summarizes the ecotoxicological effects of microplastic contaminants in aquatic environment like the oxidative damage, neurotoxicity and decreased reproductive potential. An in-depth discussion regarding the ability of the microplastics in combination with other pollutants to serve as potentially hazardous agents in aquatic environment is also elaborated in the review. Further a summary on various microplastic detection methods, challenges associated with microplastic detection and management is carefully reviewed and compiled in this work. The need for proper awareness programs to general public highlighting the toxicity of microplastics and strict regulations regarding their continuous assessment and management in waterbodies are essential factors in controlling their adverse effect on aquatic environment. 2023 Elsevier B.V.
Kumar V.; Umesh M.; Chakraborty P.; Sharma P.; Sarojini S.; Basheer T.; Kaur K.; Pasrija R.; Barcelo D.
TrAC - Trends in Analytical Chemistry, Vol-170
https://doi.org/10.1016/j.trac.2023.117392 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85179130183&doi=10.1016%2fj.trac.2023.117392&partnerID=40&md5=a0ad0de11608ef742fd33a767ca126a1
Kumar V., Bioconversion and Tissue Engineering Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Chakraborty P., School of Allied Healthcare and Sciences, Jain (Deemed to be University), Whitefield, Karnataka, Bangalore, 560066, India; Sharma P., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Sarojini S., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Basheer T., Waste Management Division, Integrated Rural Technology Centre (IRTC), Mundur, Kerala, Palakkad, 678592, India; Kaur K., Punjab Agricultural University, Institute of Agriculture, Punjab, Gurdaspur, 143521, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Rohtak, India; Barcelo D., Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research, IDAEA-CSIC, Jordi Girona, 18-26, Barcelona, 08034, Spain, Sustainability Cluster, School of Engineering, UPES, Dehradun, India
A Retrospection on Mercury Contamination, Bioaccumulation, and Toxicity in Diverse Environments: Current Insights and Future Prospects
bioaccumulation; biomarkers; ecotoxicity; mercury fate; methyl mercury conversion
Owing to various industrial applications of mercury (Hg), its release into the environment at high concentration is becoming a great threat to living organisms on a global scale. Human exposure to Hg is greatly correlated with contamination in the food chain through cereal crops and sea foods. Since Hg is a non-essential component and does not possess a biological role and exhibits carcinogenic and genotoxic behaviour, biomonitoring with a focus on biomagnification of higher living animals and plants is the need of the hour. This review traces the plausible relationship between Hg concentration, chemical form, exposure, bioavailability, bioaccumulation, distribution, and ecotoxicology. The toxicity with molecular mechanisms, oxidative stress (OS), protein alteration, genomic change, and enzymatic disruptions are discussed. In addition, this review also elaborates advanced strategies for reducing Hg contamination such as algal and phytoremediation, biochar application, catalytical oxidation, and immobilization. Furthermore, there are challenges to overcome and future perspectives considering Hg concentrations, biomarkers, and identification through the nature of exposures are recommended. 2023 by the authors.
Kumar V.; Umesh M.; Shanmugam M.K.; Chakraborty P.; Duhan L.; Gummadi S.N.; Pasrija R.; Jayaraj I.; Dasarahally Huligowda L.K.
Sustainability (Switzerland), Vol-15, No. 18
https://doi.org/10.3390/su151813292 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85172875053&doi=10.3390%2fsu151813292&partnerID=40&md5=6d5ebbbac3a63a6271f4716ff6879f0b
Kumar V., Bioconversion and Tissue Engineering Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Tamil Nadu, Chennai, 602105, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560029, India; Shanmugam M.K., Applied and Industrial Microbiology, Department of Biotechnology, Indian Institute of Technology Madras, Tamil Nadu, Chennai, 600036, India; Chakraborty P., School of Allied Healthcare and Sciences, Jain (Deemed to be) University, Whitefield, Karnataka, Bangalore, 560066, India; Duhan L., Department of Biochemistry, Maharshi Dayanand University, Haryana, Rohtak, 124001, India; Gummadi S.N., Applied and Industrial Microbiology, Department of Biotechnology, Indian Institute of Technology Madras, Tamil Nadu, Chennai, 600036, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Haryana, Rohtak, 124001, India; Jayaraj I., Department of Biotechnology, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, (SIMATS), Tamil Nadu, Chennai, 602105, India; Dasarahally Huligowda L.K., Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Uttarakhand, Roorkee, 247667, India
Bioengineering of biowaste to recover bioproducts and bioenergy: A circular economy approach towards sustainable zero-waste environment
Biowaste to energy nexus; Development of bioreactors; Microbial fuel cells; Potential microbes
The inevitable need for waste valorisation and management has revolutionized the way in which the waste is visualised as a potential biorefinery for various product development rather than offensive trash. Biowaste has emerged as a potential feedstock to produce several value-added products. Bioenergy generation is one of the potential applications originating from the valorisation of biowaste. Bioenergy production requires analysis and optimization of various parameters such as biowaste composition and conversion potential to develop innovative and sustainable technologies for most effective utilization of biowaste with enhanced bioenergy production. In this context, feedstocks, such as food, agriculture, beverage, and municipal solid waste act as promising resources to produce renewable energy. Similarly, the concept of microbial fuel cells employing biowaste has clearly gained research focus in the past few decades. Despite of these potential benefits, the area of bioenergy generation still is in infancy and requires more interdisciplinary research to be sustainable alternatives. This review is aimed at analysing the bioconversion potential of biowaste to renewable energy. The possibility of valorising underutilized biowaste substrates is elaborately presented. In addition, the application and efficiency of microbial fuel cells in utilizing biowaste are described in detail taking into consideration of its great scope. Furthermore, the review addresses the significance bioreactor development for energy production along with major challenges and future prospects in bioenergy production. Based on this review it can be concluded that bioenergy production utilizing biowaste can clearly open new avenues in the field of waste valorisation and energy research. Systematic and strategic developments considering the techno economic feasibilities of this excellent energy generation process will make them a true sustainable alternative for conventional energy sources. 2023 Elsevier Ltd
Kumar V.; Vangnai A.S.; Sharma N.; Kaur K.; Chakraborty P.; Umesh M.; Singhal B.; Utreja D.; Carrasco E.U.; Andler R.; Awasthi M.K.; Taherzadeh M.J.
ISSN: 456535; PubMed ID: 36731660; CODEN: CMSHA
https://doi.org/10.1016/j.chemosphere.2023.138005 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85147552859&doi=10.1016%2fj.chemosphere.2023.138005&partnerID=40&md5=3e573ff0ea55b0c74a4cbc701d33b178
Kumar V., Ecotoxicity and Bioconversion Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India; Vangnai A.S., Center of Excellence in Biocatalyst and Sustainable Biotechnology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand; Sharma N., Metagenomics and Bioprocess Design Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, India; Kaur K., Department of Chemistry, Punjab Agricultural University, Punjab, Ludhiana, 141004, India; Chakraborty P., School of Allied Healthcare and Sciences, Jain (Deemed to Be) University, Bangalore-66, Whitefield, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bengaluru, 560029, India; Singhal B., School of Biotechnology, Gautam Buddha University, U.P, Greater Noida, India; Utreja D., Department of Chemistry, Punjab Agricultural University, Punjab, Ludhiana, 141004, India; Carrasco E.U., Departamento de Ingenier Quica, Universidad de La Frontera, Temuco, 4811230, Chile; Andler R., Escuela de Ingenier en Biotecnolog, Centro de Biotecnolog de Los Recursos Naturales (Cenbio), Universidad Catica Del Maule, Chile; Awasthi M.K., College of Natural Resources and Environment, Northwest A&F University, Yangling, 712100, China; Taherzadeh M.J., Swedish Centre for Resource Recovery, University of Bor, Bor, 501 90, Sweden
An Integration of Satellite A Based Network with Higher Level Type Network with the use of P-P Connection: A Deep Review
6G; Aerial Access Network (AAN); Benders decomposition-based algorithm; point to point communication; Time-Expanding graphs (TEGs)
The Aerial Access 6g Network (AAN) is seen as a way to access remote and sparsely populated areas not served by traditional terrestrial networks, especially with the advent of 6G technology. This study presents a new approach for efficient data collection and transmission in point to point access networks using low earth orbit (LEO) satellites and high altitude platforms (HAPS). Incorporating LEO satellites as backlinks and HAPs as airborne base stations, the system provides low-bandwidth transmission to ground users. A Time Augmented Graph (TEG) model is proposed to represent the dynamic topology of the air access network according to time slots. With this example, this study can create an entire programming problem with the goal of maximizing data transfer to the country's data processing centre (DPC) while respecting resource constraints. Benders' decomposition-based algorithm (BDA) is proposed to solve the NP-hardness of the problem and is shown to perform well in producing near-optimal solutions. The effectiveness and efficiency of the proposed strategy is verified through simulation results performed in a realistic environment, showing high speed and performance comparable to search methods. By informing the design and optimization of future communication systems, this study will provide a better understanding of how HAP and LEO satellites work together in aerial access networks for the collection and delivery of remote terrain data. 2024 IEEE.
Kumar V.N.; Al-Attabi K.; Thakur G.; Ambrose S.; Nirsanametla Y.; Murugajothi T.
2024 4th International Conference on Advance Computing and Innovative Technologies in Engineering, ICACITE 2024, pp. 1392-1396.
Institute of Electrical and Electronics Engineers Inc.
https://doi.org/10.1109/ICACITE60783.2024.10617062 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85201820606&doi=10.1109%2fICACITE60783.2024.10617062&partnerID=40&md5=dd6d858e37b476759df8b1cf863bcd31
Kumar V.N., Cmr Technical Campus, Department of Cse, Telangana, Hyderabad, India; Al-Attabi K., The Islamic University, Najaf, Iraq; Thakur G., Uttaranchal Institute of Technology, Uttaranchal University, Department of Civil Engineering, Dehradun, 248007, India; Ambrose S., Christ (Deemed to Be University), Department of Commerce, India; Nirsanametla Y., Chitkara University, Centre of Research Impact and Outreach, Punjab, Rajpura, 140401, India; Murugajothi T., Psna College of Engineering and Technology, Department of Ece, Dindigul, India
Investigation on Constraints and Recommended Context Aware Elicitation for IoT Runtime Workflow
Context aware; Interoperability; Ontology; QoS aware; Run-time workflow; Semantic methods; Things Mark-up Language
Various technological and application challenges arise in the advancement of Internet of Things. Apart from Design and Deployment, Security also falls as a primary challenge to overcome. Device Management is becoming more complex as numerous network services to be handled. Inter-device communication for technical aspects appears to be underappreciated. There is a critical necessity to include this area's requirements and challenges. By abstracting data models and operations and expressing them using semantics, M2Mcommunication and interoperability and may be made simple. A thorough investigation of the foregoing is preparing the way for various approaches. Along with Semantics, a high-level language construct is suggested that can enable run-time workflow construction. Things Markup Language is the name of the concept (TML). 2024, Ismail Saritas. All rights reserved.
Kumar V.S.; Kulkarni S.; Mukkapati N.; Singhal A.; Tiwari M.; David D.S.
International Journal of Intelligent Systems and Applications in Engineering, Vol-12, No. 3s, pp. 96-105.
Kumar V.S., Department of Information Technology, Vel Tech Multi Tech Engineering College, Chennai, India; Kulkarni S., Department of Information Science & Engineering, Yenepoya Institute of Technolog, Karnataka, Mangaluru, India; Mukkapati N., Department of Computer Science and Engineering, Koneru Lakshmaiah Education Foundation, 522302, India; Singhal A., School of Sciences, Christ (Deemed to be University) Delhi NCR, Uttar Pradesh, Ghaziabad, 201003, India; Tiwari M., Department of Computer Science and Engineering, Bharati Vidyapeeths College of Engineering, Delhi, India; David D.S., Department of Information Technology, Vel Tech Multi Tech Engineering College, Chennai, India
A study on impact of celebrity endorsement on customer attitude towards the brand and purchase intention
Today celebrity endorsement has become a trend and been used as a winning formula and celebrities in India are the role models; people in the country are so influenced that they are attracted & follow the trends, styles also, consume the product they endorse and they associate the brand with the celebrity therefore the companies and the marketers believe that celebrity changes the purchase intention of the buyer. So this has been conducted to find out the impact of celebrity endorsement on customer attitude towards the brand and intention to purchase. To achieve the objective a questionnaire has been formed to collect the primary data of minimum of 200 respondents that will help to come to a conclusion about the impact if celebrity endorsement. The study also tries out to find out the various factors that affect a buyer purchase intention. For this study attributes of a celebrity and the brand have been studied also the attitude towards the brand. To acquire the required results the questionnaire was distributed to the target group aged 15-50 and the data collected was studied , analyzed to come to the conclusion whether celebrity influence the target group of consumers.
Data-Driven Transformation of Hospitality Supply Chains Using AI-Powered Segmentation
Artificial intelligence (AI); DBSCAN; Elbow Method; Principal Component Analysis (PCA)
The increasing complexity of supply chain operations in the hospitality sector demands data-driven strategies for efficient resource utilization and service delivery. This study proposes an artificial intelligence (AI)-driven framework leveraging unsupervised machine learning to uncover hidden patterns in patient-related operational data sourced from a publicly available dataset. The research applies clustering algorithmsK-Means, DBSCAN, and Agglomerative Hierarchical Clusteringto segment patient prof iles based on key variables such as length of stay, procedure type, room category, equipment usage, and staffing needs. Principal Component Analysis (PCA) was employed for dimensionality reduction and cluster visualization. The optimal number of clusters was identified using the Elbow Method, with K-Means yielding the highest silhouette score. Comparative analysis of all clustering models revealed varying strengths in noise detection, interpretability, and handling of sparse features. The results demonstrate how intelligent segmentation can support dynamic resource planning, targeted supply allocation, and improved operational responsiveness in hospital-based hospitality systems. This work contributes to the growing domain of AI-enabled supply chain analytics and of fers a practical pathway for enhancing decision-making in smart hospitality environments. 2025 IEEE.
Kumar, Abhinav; Khanna, Smriti; Amajala, Sai Rithwik; Upreti, Shitiz; Radhakrishnan, G.V.; Upreti, Kamal
Proceedings of International Conference on Digital Innovations for Sustainable Solutions, ICDISS 2025;
Restricted Access; Hardcopy may be available in the library
https://doi.org/10.1109/ICDISS68238.2025.11320599 https://www.scopus.com/pages/publications/105033707479?origin=resultslist
Kumar A., Data Scientist Turing, Palo Alto, CA, United States; Khanna S., School of Management Sciences, Apeejay Stya University, Haryana, Gurugram, India; Amajala S.R., Department of Computer Science, New York University, Tandon, New York, United States; Upreti S., Manav Rachna International Institute of Research & Studies (MRIIRS), Haryana, Faridabad, India; Radhakrishnan G.V., Department of Economics, Finance Kalinga School of Management KIIT, Bhubaneswar, India; Upreti K., Department of Computer Science, Christ University Delhi NCR, Delhi NCR, Ghaziabad, India