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Hidden Markov Model: Application towards genomic analysis
Hidden Markov Model (HMM) has become one of the interesting methods for the researchers, especially in bioinformatics where different analysis are carried out. These are widely used in science, engineering and many other areas such as bioinformatics, genomic mapping, computer vision, finance and economics, and in social science. HMMs require much smaller training sets, and that the examination of the inner structure of the model provides often a deeper understanding of the phenomenon. In this survey, we first describe the important algorithms for the HMMs, and provide useful comparisons, aiming at their advantages and shortcomings. We then consider the major g applications, such as annotations, gene alignment and profiling of sequences, DNA structure prediction, and pattern recognition. We also list some analysis on how to use HMM for DNA genomes. Finally, we conclude use and perspectives of HMMs in bioinformatics and provide a critical appraisal for the same. 2016 IEEE. -
Biomass Carbon Dots: Illuminating New Era in Antimicrobial Defense and Cancer Combat
The twenty-first century has witnessed remarkable advancements across diverse facets of human life, including significant progress in the medical field, economic growth, scientific breakthroughs, and technological advancements. Despite these strides that improved living standards, the persistent threat posed by pathogenic infections caused by bacteria, fungi, viruses, etc., remains a critical concern. The enduring emergence of new variations of these infections continues to impact lives profoundly. Cancer is another looming spectre that continues to challenge human health security. Consequently, extensive research endeavours aim to develop swift, efficient, and innocuous methods for curing and preventing these infections. This paper explores a burgeoning field in physics, focusing on recent advancements in nanomaterials, particularly in developing carbon dots (CDs). Characterized by their size, which is less than 10nm, CDs have proven exceptionally beneficial in diagnosing and treating life-threatening health issues while preserving the viability of healthy cells. Their versatility is evident in various biomedical applications, serving as bioimaging probes, intracellular drug delivery agents, and agents for bactericidal and fungicidal, as well as in cancer treatment and diagnosis. The key attributes contributing to their efficacy include ease of functionalization, biocompatibility, fluorescence, low cytotoxicity, and catalytic properties. As an innovative nanomaterial, CDs showcase tremendous potential in advancing medical diagnostics and therapeutics, offering a glimpse into a future where these tiny entities play a pivotal role in ensuring human well-being. This review focuses on the antibacterial, antifungal, antiviral, and anticancerous activities of the CDs derived from various precursors derived by biomass. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. -
A road map on nanostructured surface tuning strategies of carbon fiber paper electrode: Enhanced electrocatalytic applications
Impressive characteristics of carbon fiber paper (CFP) electrodes propound greater demand in electrochemical applications. CFP has a network structure composed of interwoven carbon fibers (CFs). The macroporous structure, chemical inertness, high conductivity, low cost, corrosion resistance, good electrical properties, mechanical strength, and self-standing capabilities have led to the large-scale acceptance of CFP. This review appraises the current progress of CFP based electrodes for electrocatalytic applications in the field of electrochemical sensors, electrochemical capacitors, batteries, electro Fenton oxidation, electrooxidation of alcohols, water splitting, hydrogen evolution reaction (HER), and oxygen evolution reaction (OER) together with the different fabrication strategies on the CFP substrate in an organized manner. The different modifiers used for surface tuning of CFP addressed in this review are the conducting polymers, carbon-based nanomaterials, transition metal dichalcogenides/phosphides/carbides, and nanostructured metal oxides. 2022 Vietnam National University, Hanoi -
On equitable near proper coloring of graphs
A defective vertex coloring of a graph is a coloring in which some adjacent vertices may have the same color. An edge whose adjacent vertices have the same color is called a bad edge. A defective coloring of a graph G with minimum possible number of bad edges in G is known as a near proper coloring of G. In this paper, we introduce the notion of equitable near proper coloring of graphs and determine the minimum number of bad edges obtained from an equitable near proper coloring of some graph classes. 2024 Azarbaijan Shahid Madani University. -
Design and structural characteristics of conducting polymer-metal organic framework composites for energy storage devices
The popularity of portable gadgets has increased the supply for energy storage systems with significant power and energy densities Redox-active conducting polymers (CPs) have mechanical qualities similar to polymers and electrical conductivity properties similar to metals. Unfortunately, the volume changes that occur throughout the charge and discharge procedures cause them to function poorly. An efficient method to attain high performance is to combine CPs with metal-organic frameworks (MOF) to create composites. Despite MOFs' extraordinary interior surface areas and adaptable pore structures, they have poor stability, polymers can improve MOF stability and improve other crucial characteristics like electrical conductivity. The combination of these two different components can result in a variety of desired features that are not always attained by these components individually. The recent research on conducting polymer-based metal-organic framework (CP/MOF) composites for energy storage applications is thoroughly surveyed in this review paper. This review focuses on various CP/MOF-based fuel cells, batteries and supercapacitors, pertinent fabrication techniques, and important design principles. 2023 Elsevier B.V. -
Enzyme immobilized conducting polymer-based biosensor for the electrochemical determination of the eco-toxic pollutant p-nonylphenol
The unbridled release of harmful endocrine disruptors (EDs) into the environment is deteriorating human and animal health. A facile and efficacious biosensor was developed by immobilizing laccase over electropolymerized poly anthranilic acid on a carbon fiber paper (CFP) electrode, Lac/PAA/CFP for the detection of p-nonylphenol (PNP). PNP is a persistent phenolic endocrine disruptor and a harmful eco-toxic pollutant. Physico-chemical and electrochemical characterization of the fabricated electrode was carried out to study the modification of the Lac/PAA/CFP electrode. Cyclic voltammetric studies divulged that the prepared sensor has catalytic activity approximately twice greater than that of the bare CFP electrode. The influence of pH and scan rate was scrutinized for the modified electrode. Under optimized conditions differential pulse voltammetric studies were used for the quantification and the results revealed that the biosensor has a low limit of detection (LOD) and limit of quantification (LOQ) of 1.74 nM and 5 Nm, respectively with a broad linear dynamic range of 5250 nM. In the presence of interferants, the developed biosensor exhibited good selectivity toward the electrochemical detection of PNP. Molecular docking studies carried out revealed the hydrogen bonding interaction of the Asn264 residue of laccase Trametes versicolor. Further, the fabricated biosensor was accessed for its practicality in real samples collected from tap water and lake water. 2023 Elsevier Ltd -
Rectangular microstrip antenna for WLAN application
This paper deals with the design of rectangular microstrip patch antenna for Wireless applications. In this paper a modified slotted microstrip antenna design for 2.5GHz operation is proposed. This provides improved performance in terms of lower return loss and higher gain. This is possible by inclusion of slots appropriately on the patch shape. The substrate material used in this design is Duroid5880 with permittivity 2.2 and size 47.43mm 39.65mm 1.6mm. ANSOFT HFSS EM simulator has been used for design and simulation of the microstrip antenna. The various antenna parameters such as frequency, VSWR, gain and directivity are analyzed to characterize the proposed antenna. 2015 IEEE. -
Artificial intelligence towards smart green transportation: A path towards sustainability
Emerging technological advancements and sustainability concerns have initiated the integration of smart technologies into the transportation infrastructure at major cities and tourist hubs. The rising environmental concerns have called for a shift in focus from conventional methods to innovative green transport initiatives being formulated by DMOs and destination planners. The use of data analytics and artificial intelligence in transportation has been proven to be a reasonable method for sustainable transportation. This study focuses on assessing the value propositions of smart transportation systems in enriching the tourist experience by providing convenient travel solutions. The chapter focuses on understanding the value proposition of smart transport designs at destinations and the long-term prospects of installing such sustainable infrastructure at major tourist hubs. The study also aims to evaluate the tourist experience in using smart transportation services and the potential benefits and challenges involved in the practical implementation of such systems. 2023, IGI Global. All rights reserved. -
Pressure ulcer risk assessment device /
Patent Number: 202141043299, Applicant: Vijayalakshmi A.
A pressure ulcer is a localized injury to the skin or underlying tissue as a result of unrelieved pressure which can be intrinsic or extrinsic in nature. Prevention of pressure ulcer is a prime requisite for any immobile patients as it can worsen the health situations and can even lead to mortality. In the context of Indian scenario, this issue is quite ignored either due to the lack of awareness of its implications or because of the absence of adequate preventive measures. Pressure ulcer often called as bed sores is a common issue prevalent in the immobile bed ridden, especially the old age people and the vulnerable patients with chronic medical conditions. -
Exploring character strength in the functioning and well beings of religious leaders
Positive psychology is the scientific study of optimal functioning, flourishing and well-being of individuals and organizations. The backbone of positive psychology, the character strengths are significant in effective leadership functioning. The current study explored the character strengths development and character strengths utilization in the functioning and well-being of religious leaders (consecrated nuns and priests). There were 17 participants, nine female and eight male consecrated Catholic religious leaders. The study used the mixed design. The Values in Action Tests was administrated to identify leaders top strengths and a phenomenological approach was used to explore character strengths development as well as the usage of character strengths in the functioning of the religious leaders. The findings illustrated that the most prevalent character strengths of leaders are honesty, gratitude, teamwork, fairness, and kindness. The least prevalent strengths are love of learning, humour, appreciation of excellence, zest, judgement and creativity. Results showed that the influencing factors of character strengths development are family influences, experiences at school, formative programmes in the religious formation, critical events and factors enhancing strength. The strength of wisdom and knowledge were used mainly at organizational and administrative level of leadership functioning. Strengths of courage manifested at the implementation level. The strength of humanity is identified as the most striking character strength in leader-member exchange. The strength of temperance has the role of controller in leadership functioning. The strength of justice is seen as a catalyst in promoting cohesion in the community. The leaders pivotal manifestation of the strengths of transcendence is in their intimacy with God that gives higher purpose and meaning in leadership, that is, do the Will of God. Character strengths were found in promoting wellness through achievements, facilitating total engagement, giving a great purpose in leader life and in promoting better leader-follower interactions. The highlighted character strengths that promote well-being were gratitude and appreciation. The study has brought out an ongoing leadership training programme for religious leaders that can be completed in three phases. -
Conjugate of estradiol and applications thereof /
Patent Number: US 10 , 054 , 602 B2, Applicant: Christ University.
The present invention relates to conjugate of 17-β estradiol with an analog of indocyanine green dye for the detection of cancers. The invention also provides a method of preparation of the conjugate and method of detection of cancer cells. -
Non-invasive glucometer /
Patent Number: 201941025125, Applicant: CHRIST (Deemed To Be University) -
Conjugate of Estradiol and applications thereof /
Patent Number: 201641013646, Applicant: Christ University. -
Organic and inorganic compounds anchored graphene frameworks as materials for sensor and supercapacitor applications
The specific atoms or group of atoms that can attach to the other organic or inorganic compounds due to the strong affinity is called as the anchoring group. The electrons from these organic and inorganic compounds are potent to travel through the anchor group. This leads to specific features with the change in the arrangement of atoms in the entire molecule/system. Hence, the redox reaction properties, molecular chain length and the extent of conjugation of the resultant anchored product vary. Depending upon the binding nature, anchoring groups can be divided into monodentate, bidentate, and multidentate. Among these, multidentate anchoring groups are more significant since it can bind either partially to the molecules or withthe whole surface. Though many multidentate anchoring groups like fullerene, carbon nanotubes, polymers, calixarenes, and graphene are presented in the literature, graphene oxide anchored organic and inorganic compounds are important because of its amazing contributions to the material science and design. The high thermal and electrical conductivity, large surface area, mechanical strength, and availability of more mobile electrons make graphene as the suitable anchor group for diverse applications in the field of adsorption of polluted gases, catalyst for the organic conversions, medicinal chemistry, electrochemical sensing, and energy storage devices. Therefore, Graphene oxide (GO) is one of the good choices to develop supercapacitance systems and electrochemical sensing materials. Heteroatom doping, conducting polymer, metal complexes, and metal oxides anchored graphene oxide are more significant because they change the electroactive properties significantly. Considering these, we studied the photophysical and electrochemical properties of chromium complex anchored GO synthesised by silane and diazonium coupling. The results exhibited that both silane functionalized GO and azo dye enable an electronic interaction due to the recombination of sp2 and sp3 states and electron-hole pairs which have extensive importance in developing optoelectronic devices. -
Organic and Inorganic compunds anchored graphene frameworks as materials for sensor and supercapacitor applications
The specific atoms or group of atoms that can attach to the other organic or inorganic newlinecompounds due to the strong affinity is called as the anchoring group. The electrons newlinefrom these organic and inorganic compounds are potent to travel through the anchor newlinegroup. This leads to specific features with the change in the arrangement of atoms in newlinethe entire molecule/system. Hence, the redox reaction properties, molecular chain newlinelength and the extent of conjugation of the resultant anchored product vary. Depending upon the binding nature, anchoring groups can be divided into monodentate, bidentate, and multidentate. Among these, multidentate anchoring groups are more significant since it can bind either partially to the molecules or with the whole surface. Though many multidentate anchoring groups like fullerene, carbon nanotubes, polymers, calixarenes, and graphene are presented in the literature, newlinegraphene oxide anchored organic and inorganic compounds are important because of its amazing contributions to the material science and design. The high thermal and electrical conductivity, large surface area, mechanical strength, and availability of more mobile electrons make graphene as the suitable anchor group for diverse applications in the field of adsorption of polluted gases, catalyst for the organic conversions, medicinal chemistry, electrochemical sensing, and energy storage devices. Therefore, Graphene oxide (GO) is one of the good choices to develop supercapacitance systems and electrochemical sensing materials. Heteroatom doping, conducting polymer, metal complexes, and metal oxides anchored graphene oxide are more significant because they change the electroactive properties significantly. Considering these, we studied the photophysical and electrochemical properties of chromium complex anchored GO synthesised by silane and diazonium coupling. -
Blockchain abetted supply chain management /
Patent Number: 202241004710, Applicant: Ghanesh Gunaseelan.
The invention block chain abetted'supply chain management comprising, a physical product receiver gets the information by a smart label through accessing a block of a blockchain stored on a computer system, a cold chain requirement for a product, wherein the smart label is associated with a package containing the product, the cold chain requirement ' for the product is stored in the block of the blockchain. -
Impact of management - Information - system (MIS) on effective HRM in a business /
Patent Number: 202241006289, Applicant: Dr.K.Santhana Lakshmi.
Impact of Management- Information- System (MIS) on effective HRM in a business Abstract: Human resource management is now recognised as a critical component of business. The human resources department of an ERP system has a transaction processing layer that handles tasks such as attendance tracking and wage calculation. Tracking employees is also a component of operational work. This serves as the jumping-off point for strategic work. With the increasing importance of human resource management and the growing size of businesses, maintaining employee data and producing accurate reports have become critical components of any business's operations and strategy. -
Social media as an instrument for political communication: A case study on the Kanhaiya Kumar issue /
Social Media has emerged as an essential tool of communication and has created new ways of political mobilizing and encourage social media users in political activities ranging from joining their political groups by tweeting, status update, expressing supports through blogs and videos on Youtube. Kanhaiya Kumar is the current President of the Jawaharlal Nehru University Students' Union. He is also a leader of the All India Student Federation (AISF), the student wing of the Communist Party of India (CPI). -
Studies on the Fresh Water Algal Floria in Chimmony Wildlife Sanctuary
Algae is a crucial organism in the environment. They help in maintaining the balance among different ecosystems. According to the geography and climatic conditions, newlineKerala has a suitable environment for algal growth. However, the algal biodiversity newlinestudies conducted in Kerala are significantly less. The wildlife sanctuary comprises a newlineconsiderable scope for algal biodiversity. The Chimmony wildlife sanctuary is situated in Mukundapuram taluk of Thrissur district. It spreads over 85.067 km2 with a water spread area of 10.1 km2. Ten different sampling stations were selected across newlinethe wildlife sanctuary, and extensive field visits were conducted to identify and newlinedocument the algae with respect to three seasons (pre-monsoon, monsoon, and post- newlinemonsoon). The physicochemical parameters of water like dissolved oxygen, temperature, pH, alkalinity, total dissolved solids, light intensity, and rainfall amount were estimated seasonally. In this present study, a total of 121 taxa belonging to 60 genera, 38 families, 24 orders, and 5 classes, namely Chlorophyceae, Bacillariophyceae, Euglenineae, Rhodophyceae, and Cyanophyceae, were identified from 10 different stations. The Bacillariophyceae and Chlorophyceae were the most dominant class in the study area. The algal multiplication will be more in the pre monsoon season and it was observed that the Chlorophyceaen members were dominant, while the Bacillariophyceae were dominant during the post-monsoon season. Cyanophyceae was dominant only during the monsoon season because of its sensitivity toward light. The ANOVA (Two-way) analysis showed no significant difference between stations, and there is a considerable difference between seasons for dissolved oxygen, alkalinity, temperature, and total dissolved solids. While pH, showed no significant difference between seasons and stations, light intensity showed a substantial difference between stations and seasons. The temperature and dissolved oxygen showed a negative correlation.