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Elevating pyrrole derivative synthesis: a three-component revolution
Pyrrole is an essential chemical with considerable relevance as a pharmaceutical framework for many biologically necessary medications. The growing demand for biologically active compounds calls for a simple one-pot method for generating novel pyrrole derivatives. Nots surprisingly, several multicomponent reactions (MCRs) aim to synthesize pyrrole derivatives. However, this review presents the three-component synthesis of pyrrole derivatives, highlighting the significance of multicomponent reaction in synthesizing eclectic multi-functionalised pyrrole covering the selected literature on the three-component synthesis of substituted pyrrole from 2016 to late 2023. Furthermore, this article classifies the reactions based on the starting material with functional groups involved in the pyrrole ring formation. Graphical Abstract: (Figure presented.) The Author(s), under exclusive licence to Springer Nature Switzerland AG 2024. -
Elevating pyrrole derivative synthesis: a three-component revolution
Pyrrole is an essential chemical with considerable relevance as a pharmaceutical framework for many biologically necessary medications. The growing demand for biologically active compounds calls for a simple one-pot method for generating novel pyrrole derivatives. Nots surprisingly, several multicomponent reactions (MCRs) aim to synthesize pyrrole derivatives. However, this review presents the three-component synthesis of pyrrole derivatives, highlighting the significance of multicomponent reaction in synthesizing eclectic multi-functionalised pyrrole covering the selected literature on the three-component synthesis of substituted pyrrole from 2016 to late 2023. Furthermore, this article classifies the reactions based on the starting material with functional groups involved in the pyrrole ring formation. The Author(s), under exclusive licence to Springer Nature Switzerland AG 2024. -
Elicitor and precursor-induced approaches to enhance the in vitro production of L-DOPA from cell cultures of Mucuna pruriens
Elicitation and precursor feeding are two important strategies in the in vitro techniques to enhance metabolite production to meet the demand of mankind. The secondary metabolites produced by the plants are extensively used in pharmaceutical, food and agro-chemical industries. One such metabolite is 3,4 dihydroxyphenylalanine (L-DOPA) produced from Mucuna pruriens (L.) DC. is used since ancient times to treat Parkinson's disease. Though all parts produce L-DOPA, the seed has the highest quantity. To overcome the extensive usage of the natural sources whose growth and metabolite production is highly dependent on edaphic and ecological factors, in vitro techniques like establishing cell culture for continuous production of metabolites, precursor feeding and elicitation of cell cultures to enhance the metabolite production has been reported in the present study. Callus was developed from the in vitro leaf explant and cell suspension culture was established in the liquid Murashige and Skoog's medium fortified with 0.5 mg/L picloram. Amino acid precursors like tyrosine, phenylalanine and chemical elicitors like methyl jasmonate, salicylic acid, sodium nitroprusside and silver nitrate were exposed to cell cultures for different periods (3, 6 and 9 days respectively). The precursors showed a better response in enhancing both the biomass and L-DOPA when compared to the elicitors. 500 and 1000 mg/L tyrosine showed a 1.6- and an 8.1-fold increase in biomass and L-DOPA production respectively when supplemented with MS media. However, though all the elicitors enhanced the L-DOPA production by 1.13.3-folds they did not show much significant increase in biomass. Precursor feeding approaches enhanced the metabolite considerably more than the elicitor treatment. Based on the productivity (Biomass L-DOPA conc.) precursors like Tyrosine>Phenylalanine and elicitors like Sodium nitroprusside>Silver nitrate>Methyl jasmonate>Salicylic acid showed better response. 2022 Elsevier B.V. -
Ellipse Shaped Four-Element Microstrip Patch Antenna Array Using Corporate Feed Network
The design and simulation of an ellipse-shaped four-element microstrip antenna array for effective multi-band wireless communication are presented in this paper. The proposed antenna makes use of a FR4 substrate, which has overall measurements of 240mm 150mm for a four element antenna and 55mm 55mm for a single element. Simulation of the antenna shows significant return loss at key frequencies: 0.35, 0.5, 1.7, 2.2, 3.6, 5.6, and 9.4GHz, with S11 values below ?10dB. These frequencies cover bands like radar, 4G/5G, ultra-wideband (UWB), global positioning system (GPS), and wireless LAN (WLAN). The antenna achieves broadband operation with good gain values because of the staircase-shaped ground plane and defected radiating ellipse-shaped patch. The Author(s), under exclusive license to Springer Nature Switzerland AG 2026. -
Elliptic curve-based cryptography solutions for strengthening network security in IoT environments
Elliptic Curve-Based Cryptography (ECC) may be a solid way to move forward organize security in Web of Things (IoT) settings, where other cryptography strategies regularly come up short. ECC suggests a tall level of security with moderately little key sizes, which is especially important for Internet of Things devices without any assets. This speed cuts down on preparing squander, memory utilize, and control utilize, which makes it culminate for IoT apps that utilize a part of diverse sorts of equipment. By making beyond any doubt there are secure ways to communicate and verify clients, ECC can lower the dangers of data spills and illicit get to. ECC is additionally great at securing private information over gadgets that are connected to each other since it is safe to modern dangers and can be changed to work with distinctive IoT conventions. Utilizing ECC-based arrangements in IoT systems not as it were makes them more secure, but it moreover moves forward speed, making it conceivable to receive secure and adaptable arrangements in settings that are getting more complicated and spread out. 2025, Taru Publications. All rights reserved. -
Elucidating the interplay of PPAR gamma inhibition and energy demand in adriamycin-induced cardiomyopathy: In Vitro and In Vivo perspective
Adriamycin is an anticancer anthracycline drug that inhibits the progression of topoisomerase II activity and causes apoptosis. The effective clinical application of the drug is very much limited by its adverse drug reactions on various tissues. Most importantly, Adriamycin causes cardiomyopathy, one of the life-threatening complications of the drug. Altered expression of PPAR? in adipocytes inhibited the glucose and fatty acids uptake by down regulating GLUT4 and CD36 expression and causes cardiotoxicity. Therefore, the influence of Adriamycinin cardiac ailments was investigated in vivo and in vitro. Adriamycin treated rats showed altered ECG profile, arrhythmic heartbeat with the elevated levels of CRP and LDH. Dysregulated lipid profiles with elevated levels of cholesterol and triglycerides were also observed. Possibilities of cardiac problems due to cardiomyopathy were analyzed through histopathology. Adriamycin treated rats showed no signs for atheromatous plaque formation in aorta but disorganized cardiomyocytes with myofibrillar loss and inflammation in heart tissue, indicative of cardiomyopathy. Reduced levels of antioxidant enzymes confirmed the incidence of oxidative stress. Adriamycin treatment significantly reduced glucose and insulin levels, creating energy demand due to decreased glucose and insulin levels with increased fatty acid accumulation, ultimately resulting in oxidative stress mediated cardiomyopathy. Since PPARs play a vital role in regulating oxidative stress, the effect of Adriamycin on PPAR? was analyzed by western blot. Adriamycin downregulated PPAR? in a dose-dependent manner in H9C2 cells in vitro. Overall, our study suggests that Adriamycin alters glucose and lipid metabolism via PPAR? inhibition that leads to oxidative stress and cardiomyopathy that necessitates a different therapeutic approach. 2024 Wiley Periodicals LLC. -
Elusive Healthcare and Ailing Population: An Analysis of Indias Health Policy with Reference to the Health Status of Urban Poor in Bangalore
Health is a state of mental, physical and social well-being. India is in need of a healthcare system that can fulfill the demands of over a billion people who are unable to bear the burden of the cost of healthcare. The major challenges in the countrys healthcare system are the universal access to healthcare, health equity, healthcare human resources and healthcare finance. Increasing population in cities and urban poverty has raised a strong concern in the health condition of the urban poor in particular. The speedy growth of cities in the country in conjunction with the growth of the urban poor has made this position more important at this point of time. The present study basically aimed at finding the major factors influencing urban health and healthcare. This research aims in finding out the reasons for the fragmentation of Bangalores health services with unequal distribution of resources and minimum communication between various services. This study also focuses on areas of health concern like insufficient primary healthcare, lack of referral system, insufficient public participation towards healthcare promotion, co-ordination between various governmental or non-governmental departments etc. It is mainly based on secondary data. Interview guide is used as a tool to collect primary data. Content analysis is used to analyse and describe the present scenario objectively and systematically. Bangalore has a wide infrastructure of healthcare centres but still the poorer sections of the society do not have easy access to them. A significant number of government schemes have been implemented to provide better healthcare services in Bangalore. It can be said that Bangalore has got enough health resources to serve its people. However, the urban poor do not have the necessary means to access a proper healthcare due to various reasons like the shortage of staff, medicines, diagnostic services in public sector and private healthcare expenses which are unaffordable. The government has been failing to achieve its health target in the urban areas and ultimately left the same in the hands of private health sector. The funds allocated on health are not used effectively towards improved health service delivery. Healthcare budgeting, healthcare policies, disease eradication programmes and improvement plans of primary healthcare centres and dispensaries etc. are the main areas in which the government is falling short. There is a need to empower the urban poor to maintain their rights within the context of development. A policy which is more oriented towards the partnership of private and public healthcare sectors is advisable. A universalized system to provide equitable and basic care to every individual is required. Public-Private Partnership in health sector is a key for improving the health of the population. The governments act of financing towards healthcare must in fact be increased to 2-3 per cent of GDP. As such, the present study came out with a lot of suggestions to improve the health status of urban poor. It has also made an attempt to analyse the policy issues associated with healthcare. The researcher believes that this will be definitely an addition to the existing literature on healthcare systems in India. Layout of the dissertation: The dissertation is divided into five chapters. The first chapter is the introductory part of the research. It defines the basic concepts by giving brief summary or by providing information which are necessary to understand this research. This chapter also describes the research problems which motivates the researcher to conduct the study. Second chapter reviews the literature of healthcare problems faced by the common man. It includes reviews of various articles and books contributed towards healthcare and health policies by various health experts and practitioners. The third chapter talks about the methods used to implement the research. It explains the methodological procedures such as tools for data collection, sources of data and research design which are used to carry out the study. Data analysis is the fourth chapter and this part of the research includes the analysis of the various collected data. It includes the process of inspecting and transforming of the collected data with the goal of highlighting useful information, later helping towards suggesting conclusion of the research. The final chapter presents the summary of the research with important findings and suggestions. Key words: healthcare, health policy, health status, ailing people, urban poor, cost of treatment, public health sector, private health sector, health infrastructure. -
Elusive Justice to Dalits in the 'Land of Social Justice'
The recent inhuman incident of mixing human faeces in the overhead tank supplying water to Dalit colony in Vengaivayal village in Pudukkottai district of Tamil Nadu refl ects the perpetuating violence against the Dalits. Locating this brutal violence within the larger framework of violence against Dalits in Tamil Nadu, the lackadaisical attitude of Dravidian parties when dealing with the issues related to Dalits is brought to the fore.. 2023 Economic and Political Weekly. All rights reserved. -
EM AND THE BIG HOOM by Jerry Pinto
[No abstract available] -
EM-ACO-ARM: An Enhanced Multiple Ant Colony Optimization Algorithm for Adaptive Resource Management in Cloud Environment
Ant Colony Optimization (ACO) is an intelligent algorithm ensuring optimal resource management in cloud environments. This paper proposes an enhanced version of the ACO algorithm called Enhanced Multiple Ant Colony Optimization for Adaptive Resource Management (EM-ACO-ARM). Our approach uses multiple ant colonies undergoing several iterations of optimizations to find the optimal Virtual Machine (VM) and adapt to the convergence uncertain-ties, unlike a single ant colony in the existing ACO, which can hinder Quality of Service (QoS)-based performance parameters. We conducted experiments in a cloud-simulated environment to evaluate EM-ACO-ARM in two phases. In the first phase, we computed real-time Montage tasks using the existing ACO algorithm on VMs across ten scenarios. To ensure an unbiased comparison, the same cloud configuration was maintained in the second phase, and the same tasks were computed using the proposed EM-ACO-ARM algorithm in all ten scenarios. The experimental results demonstrate that EM-ACO-ARM improves Execution Cost and Execution Time, leading to a 14.73% increase in Resource Utilization. This ultimately improves the management of cloud resources. Additionally, a stability evaluation was conducted using regression models, and it outputted EM-ACO-ARM to provide more stability than the existing ACO algorithm. The cloud can provide better QoS with the proposed EM-ACO-ARM algorithm while abiding by Service Level Agreements. 2025 The Authors. Published by Elsevier B.V. -
Embarrassment in the Context of Negative Emotions and Its Effects on Information Processing
Negative emotions are feelings of sadness arising out of negative evaluation of oneself by self or others. Embarrassment is characterized as a negative emotion which is experienced as a threat to ones social identity. This chapter discusses the differences between embarrassment and related negative emotions, namely shame, guilt and humiliation and its effects on information processing. Around 45 articles have been reviewed in the process, which were selected based on their relation to either negative emotions in general or specifically to one or more of them. The study uses the interactional (bio-psycho-social) approach to determine the antecedents and consequences of experiencing embarrassment and how it affects information processing. It further explores gender differences in the experience of negative emotions. Given that the existing evidence reveals many contradictory findings in the experience of negative emotions, this chapter conceptualizes certain factors that might influence this experience. It also provides some reasons for variations in experience of embarrassment and related negative emotions, on the basis of gender. This chapter concludes by proposing the complexity of embarrassment as an emotion and a conceptual framework of a continuum on which the experiences of embarrassment may lie and the factors determining the placement of these experiences with their cognitive implications. The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020, Corrected Publication 2020. -
Embedded Finance in Action: A Pathway to Sustainable Growth
This chapter examines how embedded finance reshapes sustainable investment through AI, machine learning, and DeFi integration with ESG practices. These technologies can address behavioral biases such as loss aversion, yet major challenges remain. ESG data is fragmented, with rating providers often showing correlations below 0.6, weakening automated screening. Greenwashing risks rise as automation favors convenience over impact checks, while regulation lags behind and leaves fiduciary duties unclear. The discussion links these issues to finance theory, applying CAPM to test whether ESG factors improve risk- adjusted returns and using behavioral insights to assess how embedded systems may correct cognitive limits. Case studies show that while embedded finance reduces transaction friction, turning convenience into measurable sustainability outcomes is still uncertain. The chapter contributes by connecting finance theory with emerging technologies to evaluate real versus promised effects on sustainable investment. 2026, IGI Global Scientific Publishing. -
Embedding behavioral biases into robo-advisory platforms-case of UAE investors
Purpose: This study aims to identify individuals' biases while making investment decisions and explore how these biases can be incorporated into a robo-advisory platform to help mitigate these biases. This paper identifies eight investment-related behavioral biases: mental accounting, gamblers fallacy, hindsight, regret aversion, disposition, trend-chasing, loss aversion and herding. Design/methodology/approach: This study uses primary data from 263 respondents across various age groups, of which approximately 50 were wealth management professionals in the UAE. A random sampling method from probability sampling is employed to gather the primary data. The identified biases serve as dependent variables; the age and income of individuals serve as the independent variables. Findings: Age and income are significantly related to mental accounting, herding, gambler fallacy and loss aversion. Existing studies on behavioral finance demonstrate that individuals who make investment decisions are susceptible to cognitive fallacies, leading to nonrational investment decisions. Practical implications: By studying these biases affecting individuals of varying ages and income levels, wealth management professionals can tailor their financial robo-advisory services to address these biases and help clients build wealth with consistent investment. Originality/value: This study uses survey-based sampling in the context of the UAE; hence, the data and analysis represent originality. 2024, Emerald Publishing Limited. -
Embedding behavioral biases into robo-advisory platforms-case of UAE investors
Purpose: This study aims to identify individuals' biases while making investment decisions and explore how these biases can be incorporated into a robo-advisory platform to help mitigate these biases. This paper identifies eight investment-related behavioral biases: mental accounting, gamblers fallacy, hindsight, regret aversion, disposition, trend-chasing, loss aversion and herding. Design/methodology/approach: This study uses primary data from 263 respondents across various age groups, of which approximately 50 were wealth management professionals in the UAE. A random sampling method from probability sampling is employed to gather the primary data. The identified biases serve as dependent variables; the age and income of individuals serve as the independent variables. Findings: Age and income are significantly related to mental accounting, herding, gambler fallacy and loss aversion. Existing studies on behavioral finance demonstrate that individuals who make investment decisions are susceptible to cognitive fallacies, leading to nonrational investment decisions. Practical implications: By studying these biases affecting individuals of varying ages and income levels, wealth management professionals can tailor their financial robo-advisory services to address these biases and help clients build wealth with consistent investment. Originality/value: This study uses survey-based sampling in the context of the UAE; hence, the data and analysis represent originality. 2024, Emerald Publishing Limited. -
Embodied Intelligence and the Phenomenology of Al
The intersection of artificial intelligence (Al), embodied cognition, and phenome-nology represents one of the most profound and complex inquiries in contemporary philosophy of mind. This chapter explores the epistemological and ontological dimensions of embodied intelligence and its relationship to the phenomenology of consciousness, with a specific focus on qualia-the subjective, first-person qualities of experience. By bridging computational models of intelligence with phenomeno-logical analyses of perception and awareness, the chapter advances an integrative framework that challenges reductionist and purely mechanistic views of cognition. It argues that consciousness, rather than emerging from disembodied computation, is fundamentally rooted in embodied, context-dependent, and experiential struc-tures. Drawing from phenomenological thinkers such as Husserl, Heidegger, and Merleau-Ponty, alongside contemporary Al paradigms including connectionism and enactivism. 2026 by IGI Global Scientific Publishing. All rights reserved. -
Embracing change: Understanding climate changes and diversity challenges
Embracing change in the context of climate change and diversity challenges is crucial for fostering resilience and promoting sustainability. Rising temperatures, extreme weather events, and sea-level rise are not just environmental issues; they amplify social inequities and economic disparities, disproportionately affecting marginalized communities. Addressing these challenges requires a commitment to environmental sustainability and the integration of diverse perspectives. Additionally, fostering cultural diversity enhances our collective knowledge and adaptive capacity, allowing for innovative solutions rooted in varied experiences and traditions. Governments and organizations must collaborate to create adaptive policies that prioritize resilience, equity, and inclusivity. Embracing change means recognizing the interconnectedness of climate issues and social dynamics, ultimately fostering a holistic approach to create a sustainable and equitable future for all. By understanding these challenges, we can navigate the complexities of change and emerge stronger together. 2025, IGI Global Scientific Publishing. All rights reserved. -
Embracing edge computing: Elevating marketing intelligence across Asian business horizons
This research paper investigates the transformative potential of Edge Computing within the Asian business landscape, with a specific focus on India and China. It also aims to understand the implications of edge computing in the domain of market intelligence in the Asian business setup. The study falls into the category of exploratory research. It is based on the systematic review of academic literature related to edge computing and frontier technology advancements in Asian countries. The findings suggest that Edge Computing has the potential to bridge the technology gap in Asia, offering governments and businesses the means to reach wider audiences and accelerate innovation. Edge Computing is in the early stages of mass adoption, especially in the Asian context. Hence, this viewpoint article sets itself apart by enunciating the structure and approach in which the Asian business landscape can make use of edge technologies. The practical implications of this study lie in its potential to inform policymakers, businesses and technology innovators in Asia about the opportunities presented by Edge Computing. By understanding the tailored approaches taken by India and China, stakeholders can better harness Edge Computing to drive economic development, bridge technology disparities and enhance their global competitiveness. 2025 Priyakrushna Mohanty and Khushi Vasudev. All rights reserved. -
Embracing intelligent machines: Aqualitative study to explore thetransformational trends inthe workplace
Purpose: With Industry 4.0 and the extensive rise of smart technologies, we are seeing remarkable transformations in work practices and workplaces. Scholars report the phenomenal progress of smart technologies. At the same time, we can hear the rhetoric emphasising their potential threats. This study focusses on how and where intelligent machines are leveraged in the workplace, how humans co-working with intelligent machines are affected and what they believe can be done to mitigate the risks of the increased use of intelligent machines. Design/methodology/approach: We conducted in-depth interviews with 15 respondents working in various leadership capacities associated with intelligent machines and technologies. Using NVivo, we coded and churned out the themes from the qualitative data collected. Findings: This study shows how intelligent machines are leveraged across different industries, ranging from chatbots, intelligent sensors, cognitive systems and computer vision to the replica of the entire human being. They are used end-to-end in the value chain, increasing productivity, complementing human workers skillsets and augmenting decisions made by human workers. Human workers experience a blend of positive and negative emotions whilst co-working with intelligent machines, which influences their job satisfaction level. Organisations adopt several anticipatory strategies, like transforming into a learning organisation, identifying futuristic technologies and upskilling their human workers, regularly conducting social learning events and designing accelerated career paths to embrace intelligent technologies. Originality/value: This study seeks to understand the emotional and practical implications of the use of intelligent machines by humans and how both entities can integrate and complement each other. These insights can help organisations and employees understand what future workplaces and practices will look like and how to remain relevant in this transformation. 2024, Sumathi Annamalai and Aditi Vasunandan. -
Embracing Sustainability: Role of Corporate Social Responsibility in Promoting Green Growth Amidst a Competitive Business Environment in India
In today's ever-evolving business environment, the synergy between corporate achievement and societal accountability highlights the critical importance of integrating sustainability through Corporate Social Responsibility (CSR). This article explores CSR's pivotal role in cultivating green growth amid the intricacies of a highly competitive business environment. Starting with an examination of CSR's evolution and components, the narrative highlights the need for a paradigm shift in business strategies amidst global challenges like climate change and resource scarcity. Central to this transformation is the integration of sustainable practices, emphasizing eco-friendly measures and operational efficiency. The article delves into the multifaceted benefits of CSR, illustrating how companies can shape a positive corporate image by aligning with consumer preferences and ethical considerations. Crucial elements such as stakeholder engagement and collaboration are emphasized, showcasing successful CSR initiatives that foster sustainable development through cooperative efforts. Additionally, the article underscores CSR's role in navigating the evolving regulatory landscape, emphasizing the importance of proactive compliance for sustained business viability. In an era where investors increasingly consider Environmental, Social, and Governance (ESG) criteria, the article positions CSR as a magnet for socially responsible investments. It elucidates how a commitment to sustainable practices not only attracts investors but also fuels innovation, fostering market differentiation and enhancing a company's competitive edge. Ultimately, the article contends that incorporating CSR into corporate strategy is not merely a response to societal expectations but a strategic imperative for businesses seeking resilience, relevance, and prosperity amidst intense competition and global challenges. The Author(s), under exclusive license to Springer Nature Switzerland AG 2025. -
Emergence of women chefs and their status in the hotel industry: A study with special reference to Bengaluru /
International Journal of Advance Research In Computer Science And Management Studies, Vol.6, Issue 2, pp.50-57, ISSN No:2321-7782.