Classification of Alzheimer's Disease Stages Using Machine Learning Techniques

Title

Classification of Alzheimer's Disease Stages Using Machine Learning Techniques

Creator

Febin, Antony

Contributor

H B, Anita

Description

Alzheimer s disease (AD) is a type of mental disorder which deteriorates the normal functioning of human brain by reducing the memory capacity of an individual. Age is the most common factor for AD and this disease cannot be reversed or stopped. Doctors can only treat the symptoms of AD which include personality changes and brain structural changes. Analyzing neuro-degenerative disorders, neuroimaging plays an important role in diagnosing subjects with AD and other stages of AD. The proposed research identified this gap and using MRI and PET newlineimages for recognizing AD in its early occurrences by the professionals. This helps in tailoring an appropriate treatment procedure for treating AD. As per literature survey, many researchers have worked with convolutional methods like inbuilt skull stripping with two or more conversions and classified with different CNN architectures. The proposed research experimented advanced skull stripping method and classified using deep learning architectures. This research emphasizes the implementation of ResNet50 architecture with T1 weighted MRI and Amyloid PET images for detecting the abnormalities in the brain patterns based on the image attributes. For the proposed experiment, a total of 5000 T1 weighted MRI data and 3000 newlineAmyloid PET data were used. The collected images were pre-processed with noise removal newlinetechniques and skull stripping method. The ResNet50 is used to classify AD from the data newlineobtained from the ADNI dataset. Pre-processed images /data were fed to the tuned for three class classification on ADNI image data at 200 Epochs shows the accuracy of 97.3% for T1 weighted MRI data and 98% for Amyloid PET data. The experimental results of the proposed model prove that it classifies the images according to various stages with better accuracy than the other existing models by achieving excellent results.

Source

Author's Submission

Date

2024-01-01

Publisher

Christ(Deemed to be University)

Subject

Computer Science

Rights

Open Access

Relation

61000290

Format

PDF

Language

English

Type

PhD

Identifier

http://hdl.handle.net/10603/547684