Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource PHD PhD PhD Thesis Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Relation A related resource 61000318 Title A name given to the resource Occupational Exposure to Cooking Oil Fumes : Biochemical, Cytogenetic and Molecular Signatures Subject The topic of the resource Life Sciences Description An account of the resource Occupational exposure to Cooking Oil Fumes (COFs) is a widespread concern in the newlineculinary industry, and it has raised significant health apprehensions due to its potential adverse effects on individuals working in kitchens. This current research presents a comprehensive analysis of the biochemical, cytogenetic, and molecular analysis observed in individuals exposed to COFs in their workplace. The study employed a cross-sectional approach, involving a cohort of kitchen personnel working in diverse culinary settings. Biochemical assessments focused on analyzing blood parameters, such as lipid profiles, liver enzymes, and markers of oxidative stress, to gauge the impact of COFs on the participants systemic health. Cytogenetic investigations encompassed the assessment of chromosomal aberrations and micronuclei frequency in peripheral blood lymphocytes, shedding light on potential genotoxicity associated with COF exposure. Moreover, molecular analyses involved the examination of ApoE and BMAL1 gene expression patterns related to inflammation, oxidative stress response, and detoxification pathways also this aspect aimed to uncover the newlineunderlying molecular mechanisms influenced by COFs. Preliminary results suggest a significant association between COF exposure and alterations in biochemical parameters, newlineparticularly an increase in oxidative stress markers and changes in lipid profiles, indicative of potential cardiovascular risks. Cytogenetic assessments revealed an elevated frequency of chromosomal aberrations and micronuclei formation, highlighting genotoxic effects linked to COF exposure. Molecular investigations demonstrated differential expression patterns of ApoE and BMAL1 genes involved in inflammation and oxidative stress responses, further corroborating the adverse effects of COFs on cellular processes. The findings of this research underscore the importance of addressing occupational exposure to COFs and implementing appropriate safety measures in cooking area. Creator An entity primarily responsible for making the resource Chaudhary, Aditi Source A related resource from which the described resource is derived Author's Submission Publisher An entity responsible for making the resource available Christ(Deemed to be University) Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Contributor An entity responsible for making contributions to the resource P, Manikantan Rights Information about rights held in and over the resource Open Access Format The file format, physical medium, or dimensions of the resource PDF Language A language of the resource English Type The nature or genre of the resource PhD Identifier An unambiguous reference to the resource within a given context <a href="http://hdl.handle.net/10603/563525" target="_blank" rel="noreferrer noopener">http://hdl.handle.net/10603/563525</a>