Nanomaterial - Based Electrochemical Sensor for Monitoring Potential Biomakers of Chronic Disorders

Title

Nanomaterial - Based Electrochemical Sensor for Monitoring Potential Biomakers of Chronic Disorders

Creator

Rijo, Rajeev

Contributor

Varghese, Anitha

Description

Detecting various biomarkers in the health industry and the biomedical sector has been newlinesignificant due to their crucial role in diagnosing, assessing, exposing, and treating disorders. This work reports electrochemical sensors for detecting biomarkers using different modifications (2D materials and nanomaterials) on carbon fiber paper electrode-based (CFPE) sensors. Adopting these modifications on the CFPE electrode greatly intensified the oxidation and reduction of peak current values. The physio-chemical characterizations of the designed electrodes were examined employing Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Electron Diffraction X-ray (EDX), X-Rayv Photoelectron spectroscopy (XPS), Fourier Transform Infrared Spectroscopy (FTIR), and Raman Spectroscopy. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) newlineassisted in optimizing the electrochemical properties via Nyquist plots, sensing performance, scan rate effect, and pH effect. Both electro-activity studies and Nyquist plots confirmed the enhancement in the electroanalytical performance of the fabricated electrodes. Real sample newlinestudies were successfully analyzed using developed electrodes, producing good recovery newlinepercentages. Overall, all the works conducted have been established to be facile and selective, with novelty in the fabrication of ultrasensitive voltammetric-based sensors to quantify different biomarkers.

Source

Author's Submission

Date

2024-01-01

Publisher

Christ(Deemed to be University)

Subject

Chemistry

Rights

Open Access

Relation

61000411

Format

PDF

Language

English

Type

PhD

Identifier

http://hdl.handle.net/10603/608677