Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Surface modified CaO nanoparticles with CMC/D-carvone for enhanced anticancer, antimicrobial and antioxidant activities Subject The topic of the resource Anti-cancer; Antimicrobial; Antioxidant; CaO nanoparticles; CMC; D-carvone Description An account of the resource The rising prevalence of antimicrobial resistance and the continued challenge to cancer therapy are in desperate need of developing innovative therapeutic strategies. In this regard, the present research work focuses on the development of CaO NPs and CaO-CMC-Dcar nanocomposites for enhanced antimicrobial and anti-cancer activities. CaO nanoparticles were synthesized by facile one pot chemical approach and eventually functionalized with CMC and D-carvone biomolecules. XRD analysis revealed that the crystallite size for CaO and CaO-CMC-Dcar nanoparticles was found to be 21.18 nm and 17.02 nm respectively. The band gap values obtained for CaO and CaO-CMC-Dcar nanoparticles were 4.44 eV, and 4.25 eV respectively. The CaO-CMC-Dcar nanoparticles show absorption maxima at 292 nm, slightly red-shifted from bare CaO nanoparticles. HRTEM and SEM analysis revealed that the prepared samples were roughly spherical and agglomerated in nature. Antimicrobial activity was evaluated against methicillin-resistant Staphylococcus aureus (MRSA) and Candida albicans. The zone of inhibition (ZOI) for CaO-CMC-Dcar nanoparticles against MRSA and C. albicans was 20.1 0.3 mm and 21.1 0.2 mm, respectively, significantly higher than that of pure CaO nanoparticles (14.1 0.2 mm and 13.2 0.1 mm) and comparable to standard anti-bacterial streptomycin and antifungal fluconazole discs. Anticancer activity was assessed via MTT assay against MOLT-4 blood cancer cells, where the IC50 values for CaO and CaO-CMC-Dcar nanoparticles were 22.6 ?g/mL and 21.54 ?g/mL, respectively. Additionally, CaO-CMC-Dcar nanoparticles exhibited enhanced antioxidant activity (80 %) compared to CaO (70 %) at 20 ?g/mL, with performance comparable to that of Vitamin C. Experimental results revealed that the CaO-CMC-Dcar nanoparticles exhibited superior biological activity compared to pure CaO nanoparticles. 2025 Indian Chemical Society Creator An entity primarily responsible for making the resource Suresh M.; Alothaim A.S.; Alfaleh F.A.; Alsowayeh N.; Suresh K.; Thangavelu I.; Arulselvan P. Source A related resource from which the described resource is derived Journal of the Indian Chemical Society, Vol-102, No. 2 Publisher An entity responsible for making the resource available Elsevier B.V. Date A point or period of time associated with an event in the lifecycle of the resource 2025-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.jics.2025.101586" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.jics.2025.101586</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85216075049&amp;doi=10.1016%2Fj.jics.2025.101586&amp;partnerID=40&amp;md5=e93a7584154a23d407474168216367d9" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85216075049&amp;doi=10.1016%2fj.jics.2025.101586&amp;partnerID=40&amp;md5=e93a7584154a23d407474168216367d9</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 194522; CODEN: JICSA Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Suresh M., Department of Biology, College of Science- Al-Zulfi, Majmaah University, Riyadh Region, Majmaah, 11952, Saudi Arabia; Alothaim A.S., Department of Biology, College of Science- Al-Zulfi, Majmaah University, Riyadh Region, Majmaah, 11952, Saudi Arabia; Alfaleh F.A., Department of Biology, College of Science- Al-Zulfi, Majmaah University, Riyadh Region, Majmaah, 11952, Saudi Arabia; Alsowayeh N., Department of Biology, College of Science- Al-Zulfi, Majmaah University, Riyadh Region, Majmaah, 11952, Saudi Arabia; Suresh K., Department of Pharmaceutics, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai, 600 116, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, (560029), India; Arulselvan P., Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 602105, India