Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource TiO2-sodium alginate core-shell nanosystem for higher antimicrobial wound healing application Subject The topic of the resource Sodium alginate; Titanium dioxide; Wound healing Description An account of the resource Wounds that are not properly managed can cause complications. Prompt and proper care is essential, to prevent microbial infection. Growing interest in metal oxide nanoparticles (NPs) for innovative wound treatments targeting healing and microbial infections. In this research, sodium alginate-coated titanium dioxide (TiSA) NPs are synthesized through a green co-precipitation method, combining inorganic TiO2 (Titanium dioxide) and SA (sodium alginate). Analysis via XRD and TEM revealed that the resulting TiSA NPs possessed an anatase phase and polygonal structure, respectively. Biomedical investigations demonstrated that TiSA NPs exhibited enhanced antimicrobial activity compared to the positive control, as well as its counterparts, and showed higher wound healing capabilities compared to TiO2 NPs. The antimicrobial effectiveness of TiSA NPs relied on various physicochemical factors, including small particle size, an altered band gap, and the presence of oxygen vacancies, resulting in microbial cell death. Moreover, TiSA NPs treatment demonstrated higher wound healing activity (98 1.09 %) compared to its counterparts after 24 h of incubation. Assessment of cytotoxicity on healthy fibroblast cells (L929) revealed that TiSA NPs exhibited lower toxicity compared to TiO2 NPs. These findings support the potential of TiSA NPs as promising agents for antimicrobial activity and wound healing. 2025 Elsevier B.V. Creator An entity primarily responsible for making the resource Menon S.V.; Sandhwar V.; Chaudhary S.; Bhanot D.; Arulselvan P.; Govindasamy C.; Khan M.I.; Suriyaprakash J.; Thangavelu I.; Boopathi T.S. Source A related resource from which the described resource is derived International Journal of Biological Macromolecules, Vol-300 Publisher An entity responsible for making the resource available Elsevier B.V. Date A point or period of time associated with an event in the lifecycle of the resource 2025-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.ijbiomac.2025.139923" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.ijbiomac.2025.139923</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85216208659&amp;doi=10.1016%2Fj.ijbiomac.2025.139923&amp;partnerID=40&amp;md5=183ff51e424fd6d0a1b4a70a6257596f" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85216208659&amp;doi=10.1016%2fj.ijbiomac.2025.139923&amp;partnerID=40&amp;md5=183ff51e424fd6d0a1b4a70a6257596f</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 1418130; PubMed ID: 39824397; CODEN: IJBMD Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Menon S.V., Department of Chemistry and Biochemistry, JAIN (Deemed-to-be University), Karnataka, Bangalore, 560069, India; Sandhwar V., Department of Chemical Engineering, PIT, Parul University, Gujarat, Vadodara, 391760, India; Chaudhary S., Department of Sciences, Vivekananda Global University, Jaipur, 303012, India; Bhanot D., Centre of Research Impact and Outcome, Chitkara University, Punjab, Rajpura, 140417, India; Arulselvan P., Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Tamil Nadu, Chennai, 602 105, India; Govindasamy C., Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia; Khan M.I., Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia; Suriyaprakash J., Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006, China; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, 560029, India; Boopathi T.S., Department of Chemistry, Amrita School of Physical Sciences, Amrita Vishwa Vidyapeetham, Coimbatore, 641112, India, Functional Materials Laboratory, Amrita School of Engineering, Amrita Vishwa Vidyapeetham, Coimbatore, 641112, India