Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 10-camphor sulfonic acid: A simple and efficient organocatalyst to access anti-SARS-COV-2 Benzoxanthene derivatives Subject The topic of the resource Benzoxanthene synthesis; Camphor Sulfonic acid; Molecular docking; Molecular dynamics simulation; Organocatalyst; Pharmaceutical applications Description An account of the resource 10-Camphor sulfonic acid (10-CSA) has gained popularity as an organocatalyst due to its broad range of solubility and user-friendliness. Affordable multicomponent reactions (MCRs) for the preparation of benzoxanthenes (4a-4 h) (5a-5i) are presented in this work. Extensive investigations and records have been conducted on the diverse biological features exhibited by xanthenes and benzoxanthenones, such as their antiviral, antibacterial, and anti-inflammatory capabilities.Using ?-naphthol, dimedone, and aldehydes, we demonstrate a cost-effective and environmentally friendly catalytic method. Under ideal circumstances, the 10-CSA catalyzes one-pot reaction, procuring impressive amounts of benzoanthenes (8595 %). All the synthesized compounds were characterized by 1H NMR and 13C NMR. A wide variety of suitable chemicals, simple work-up procedures, and solvent-free synthesis outperforms numerous existing methods for procuring biologically relevant benzoxanthene derivatives are some of the interesting features of this organocatalyzed bronsted acid process. Therefore this synthesis is industrially inevitable. Furthermore, computational studies such as molecular docking and ADMET data analysis were performed on a number of the synthesized benzoxanthene molecules. This has led to the identification of the most potent synthetic against the SARS-CoV-2 spike protein. Additionally, to mimic how medicinal compounds interact to target proteins, computational docking and dynamics techniques were used. These studies showed that, in terms of binding affinity and other crucial traits, 4a, 4b, and 5a are potential possibilities. Overall, the current study should be of great help in the development of benzoxanthene analogs which can be potential drugs for treatment of COVID-19. 2024 Elsevier B.V. Creator An entity primarily responsible for making the resource M J.; Devasia J.; Chinnam S.; Nizam A.; Periyasamy G.; Wadhwa P.; Krishna S.B.N. Source A related resource from which the described resource is derived Molecular Catalysis, Vol-572 Publisher An entity responsible for making the resource available Elsevier B.V. Date A point or period of time associated with an event in the lifecycle of the resource 2025-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.mcat.2024.114691" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.mcat.2024.114691</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85210544608&amp;doi=10.1016%2Fj.mcat.2024.114691&amp;partnerID=40&amp;md5=c321d9086b2f9405ab0018b16732da58" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85210544608&amp;doi=10.1016%2fj.mcat.2024.114691&amp;partnerID=40&amp;md5=c321d9086b2f9405ab0018b16732da58</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 24688231; CODEN: MCOAD Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant M J., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Devasia J., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Chinnam S., Department of Chemistry, M S Ramaiah Institute of Technology (Affiliated to Visvesvaraya Technological University, Belgaum), Karnataka, Bengaluru, 560054, India; Nizam A., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Periyasamy G., Department of Chemistry, Bangalore University, Karnataka, Bengaluru, 560056, India; Wadhwa P., Department of Chemistry, Lovely Professional University, Jalandhar-Delhi G.T. Road, Punjab, Phagwara, 144411, India; Krishna S.B.N., Faculty of Health Sciences, Durban University of Technology, Durban, 4000, South Africa