Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Fabrication of NiO nanoparticles modified with carboxymethyl cellulose and D-carvone for enhanced antimicrobial, antioxidant and anti-cancer activities Subject The topic of the resource Antibacterial activity; Antioxidant activity; Carboxymethyl cellulose; Colon cancer; D-carvone; HCT-116 cells; NiO nanoparticles Description An account of the resource Colon cancer is a deadly disease while pathogens such as Klebsiella pneumoniae (K. pneumoniae), Shigella dysenteriae (S. dysenteriae), Bacillus subtilis (B. subtilis), Staphylococcus aureus (S. aureus), and Candida albicans (C. albicans) are serious threat to the human health due to their persistent nature and resistant to conventional drugs. This study aims to develop NiO nanoparticles via single one pot chemical approach and to modifying them with natural molecules carboxymethyl cellulose and D-carvone to enhance antioxidant, anticancer and antibacterial activity. The NiO and NiO-CMC-Dcar exhibit fcc structure confirmed by XRD. The band gap values were found be 4.15 eV for NiO and 4.23 eV for NiO-CMC-Dcar nanocomposite. DLS study confirmed that the mean particles diameter of NiO and NiO-CMC-Dcar were 154.1 nm and 130.3 nm respectively. The TEM and SEM analysis confirmed that both NiO and NiO-CMC-Dcar samples were roughly spherical. PL emission spectra of NiO-CMC- Dcar nanoparticles at 426 nm and 506 nm indicate the electronic structural modification due to incorporation of CMC and Dcar molecules in to NiO materials. The green emission observed at 506 nm is due to oxygen vacancy that can be correlated to production of more reactive oxygen species (ROS) to kill microorganism. The experimental results show that the NiO-CMC- Dcar nanoparticles exhibit enhanced antimicrobial, anticancer and antioxidant activity when compared to NiO alone. 2024 Elsevier B.V. Creator An entity primarily responsible for making the resource Falemban A.H.; Abdel Aziz Ibrahim I.; Bamagous G.A.; Alzahrani A.R.; Shahid I.; Shahzad N.; Hasan Hussein-Al-Ali S.; Arulselvan P.; Thangavelu I. Source A related resource from which the described resource is derived Inorganic Chemistry Communications, Vol-171 Publisher An entity responsible for making the resource available Elsevier B.V. Date A point or period of time associated with an event in the lifecycle of the resource 2025-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.inoche.2024.113517" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.inoche.2024.113517</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85209637688&amp;doi=10.1016%2Fj.inoche.2024.113517&amp;partnerID=40&amp;md5=b82e768923e7cf4ce00fd19a54852578" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85209637688&amp;doi=10.1016%2fj.inoche.2024.113517&amp;partnerID=40&amp;md5=b82e768923e7cf4ce00fd19a54852578</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 13877003; CODEN: ICCOF Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Falemban A.H., Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Al-Abidiyah, P.O.Box 13578, Makkah, 21955, Saudi Arabia; Abdel Aziz Ibrahim I., Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Al-Abidiyah, P.O.Box 13578, Makkah, 21955, Saudi Arabia; Bamagous G.A., Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Al-Abidiyah, P.O.Box 13578, Makkah, 21955, Saudi Arabia; Alzahrani A.R., Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Al-Abidiyah, P.O.Box 13578, Makkah, 21955, Saudi Arabia; Shahid I., Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Al-Abidiyah, P.O.Box 13578, Makkah, 21955, Saudi Arabia; Shahzad N., Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Al-Abidiyah, P.O.Box 13578, Makkah, 21955, Saudi Arabia; Hasan Hussein-Al-Ali S., Department of Chemistry, Faculty of Sciences, Isra University, Amman, 11622, Jordan; Arulselvan P., Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 602105, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India