Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Mn2(CO)10 catalyzed visible-light-promoted synthesis of 1H-pyrazole-4-carboxamides; A sustainable multi-component statergy with antibacterial and cytotoxic evaluations Subject The topic of the resource 1H-pyrazole-4-carboxamides; Antimicrobial activity; Cytotoxicity; E. coli; P. aeruginosa Description An account of the resource Multicomponent reactions play a pivotal role in synthesizing 1H-pyrazole-4-carboxamides, underscoring its significance in sustainable organic synthesis. These compounds, valued for their diverse biological activities, have garnered substantial attention in pharmaceutical research. A facile, rapid one-pot strategy to access an extensive array of 1H-pyrazole-4-carboxamide derivatives, utilizing substituted aldehydes, cyanoacetamide, and hydrazine hydrate as substrates and a readily accessible Mn2(CO)10 as photocatalyst in EL: H2O (1:1). Among the synthesized series, products 4b, 4 g, 4k showed remarkable antibacterial activity against E coli, P aeruginosa, S. aureus in agar medium and excellent cytotoxicity with Human colorectal carcinoma (HCT-116), Liver cancer cells (Hep-G2) and breast adenocarcinoma (MCF-7) cell lines. The current method is characterized by its affordability, non-toxicity, easy access to starting materials, and notably with minimal waste generation. Additionally, remarkable aspects include its mild operating conditions, environmentally friendly nature, and the ability to accommodate a wide range of both electron-donating and electron-withdrawing groups. 2024 The Author(s) Creator An entity primarily responsible for making the resource Govindaraju S.; Ramaraj S.G.; Servesh A.; Rajprasad J.; Kumar N.; Sadaiyandi V.; Tabassum S. Source A related resource from which the described resource is derived Journal of Organometallic Chemistry, Vol-1022 Publisher An entity responsible for making the resource available Elsevier B.V. Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.jorganchem.2024.123384" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.jorganchem.2024.123384</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85204361538&amp;doi=10.1016%2Fj.jorganchem.2024.123384&amp;partnerID=40&amp;md5=8622fe571b78b52e8356e14a984176ed" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85204361538&amp;doi=10.1016%2fj.jorganchem.2024.123384&amp;partnerID=40&amp;md5=8622fe571b78b52e8356e14a984176ed</a> Rights Information about rights held in and over the resource All Open Access; Hybrid Gold Open Access Relation A related resource ISSN: 0022328X; CODEN: JORCA Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Govindaraju S., Department of Sciences and Humanities, Christ University, School of Engineering and Technology, Kumbalagodu, Mysore Road, Bengaluru, 560074, India; Ramaraj S.G., Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Japan, Department of Materials Physics, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMTS), Thandalam, Tamilnadu, Chennai, 602105, India; Servesh A., Department of Chemistry, Christ University, Hosur Road, Bengaluru, 560029, India; Rajprasad J., Department of Civil Engineering, College of Engineering and Technology, SRM Institute of Science and Technology, Tamilnadu, Kattankulathur, 603203, India; Kumar N., Department of Electronics &amp; Communication Engineering, Graphic Era Deemed to be University, Uttarakhand, Dehradun, 248002, India; Sadaiyandi V., Department of physics and nanotechnology, SRM Institute of Science and Technology kattankulathur, Tamilnadu, Chengalpattu, India; Tabassum S., Department of Chemistry, Surana College - Autonomous, South End Road, Basavanagudi, Bengaluru, 560004, India