Comprehensive study of the physicochemical properties of three-component deep eutectic solvents and their implications for microbial and anticancerous activity
- Title
- Comprehensive study of the physicochemical properties of three-component deep eutectic solvents and their implications for microbial and anticancerous activity
- Creator
- Kumar S L.; Puneeth V.; Tabassum S.; Govindaraju S.
- Description
- Sustainable chemistry centers on substituting perilous solvents and materials with eco-conscious alternatives. Deep eutectic solvents (DES) hold substantial potential in this arena. This inquiry includes the formulation of three-component eutectic solvents and an exhaustive scrutiny of their physical and chemical attributes. These encompass solubility, boiling point, pH, density, viscosity, surface tension, refractive index, contact angle, conductivity, Fourier-transform infrared spectroscopy, polarized optical microscopy, thermogravimetric analysis, and differential scanning calorimetry. Furthermore, a biological exploration featured two bacterial strains and two fungal strains. The entire spectrum of ten three-component DES was administered to these microorganisms to discern plausible impacts. In addition, the biomedical promise of these DES was unveiled through anticancer assays employing MCF-7 and HeLa cell lines. The outcomes were favorable, underscoring robust anticancer potency, thereby hinting at future oncological utility. These interdisciplinary endeavors envelop the progression of sustainable solvent innovation, meticulous physicochemical scrutiny, microbial analysis, and anticancer appraisal. This study propels inventive resolutions with ecological and biomedical reverberations by amalgamating these distinct yet interconnected facets. 2024 Indian Chemical Society
- Source
- Journal of the Indian Chemical Society, Vol-101, No. 11
- Date
- 2024-01-01
- Publisher
- Elsevier B.V.
- Subject
- Choline chloride; Deep eutectic solvents; Green chemistry; Physicochemical properties; Sustainable solvents
- Coverage
- Kumar S L., Department of Chemistry, CHRIST University, Bengaluru, 560029, India; Puneeth V., Department of Mathematics, CHRIST University, Bengaluru, 560029, India; Tabassum S., Department of Chemistry, Surana College, Bengaluru, 560074, India; Govindaraju S., Department of Sciences and Humanities, CHRIST University, Bengaluru, 560074, India
- Rights
- Restricted Access
- Relation
- ISSN: 194522; CODEN: JICSA
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Kumar S L.; Puneeth V.; Tabassum S.; Govindaraju S., “Comprehensive study of the physicochemical properties of three-component deep eutectic solvents and their implications for microbial and anticancerous activity,” CHRIST (Deemed To Be University) Institutional Repository, accessed March 17, 2025, https://archives.christuniversity.in/items/show/12744.