Immobilized proline-based electro-organocatalyst for the synthesis of bis-?-diketone via Knoevenagel condensation reaction
Bis-?-diketone; Electro-organic synthesis; Electro-organocatalyst; Knoevenagel condensation; L-proline
In the quest for more sustainable chemical processes, we devised a technique using electro-organocatalysis to synthesize bis-?-diketone compounds via Knoevenagel condensation of benzaldehyde and dimedone. Our approach involves a modified electrode fabricated via anchoring L-proline onto a carbon fiber paper electrode supported by poly-3,4-diaminobenzoic acid (PDABA), which enhances efficiency in addition to the simple catalyst separation from the reaction mixture in heterogeneous catalysis. The electrochemical and surface topographical studies for the fabricated electrode were carried out, revealing high efficiency in comparison to the bare carbon fiber paper electrode. This electrochemical reaction operates under mild conditions utilizing lithium perchlorate and acetonitrile, yielding high amounts of the desired product. This study showcases a promising pathway for producing valuable organic compounds in an environmentally friendly manner, marking a significant stride forward in sustainable synthesis practices. 2024 Elsevier Ltd
https://doi.org/10.1016/j.electacta.2024.144999 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85203020911&doi=10.1016%2fj.electacta.2024.144999&partnerID=40&md5=60971b9cd5d15f802404a9b441d02fc7
Thadathil D.A., Department of Chemistry, CHRIST University, Karnataka-, Bengaluru, 560029, India; Varghese A., Department of Chemistry, CHRIST University, Karnataka-, Bengaluru, 560029, India