Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Phytofabricated bimetallic synthesis of silver-copper nanoparticles using Aerva lanata extract to evaluate their potential cytotoxic and antimicrobial activities Description An account of the resource In this study, we demonstrate the green synthesis of bimetallic silver-copper nanoparticles (AgCu NPs) using Aerva lanata plant extract. These NPs possess diverse biological properties, including in vitro antioxidant, antibiofilm, and cytotoxic activities. The synthesis involves the reduction of silver nitrate and copper oxide salts mediated by the plant extract, resulting in the formation of crystalline AgCu NPs with a face-centered cubic structure. Characterization techniques confirm the presence of functional groups from the plant extract, acting as stabilizing and reducing agents. The synthesized NPs exhibit uniform-sized spherical morphology ranging from 7 to 12nm. They demonstrate significant antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa, inhibiting extracellular polysaccharide secretion in a dose-dependent manner. The AgCu NPs also exhibit potent cytotoxic activity against cancerous HeLa cell lines, with an inhibitory concentration (IC50) of 17.63gmL?1. Additionally, they demonstrate strong antioxidant potential, including reducing capability and H2O2 radical scavenging activity, particularly at high concentrations (240gmL?1). Overall, these results emphasize the potential of A. lanata plant metabolite-driven NPs as effective agents against infectious diseases and cancer. 2024, The Author(s). Creator An entity primarily responsible for making the resource Thirumoorthy G.; Balasubramanian B.; George J.A.; Nizam A.; Nagella P.; Srinatha N.; Pappuswamy M.; Alanazi A.M.; Meyyazhagan A.; Rengasamy K.R.R.; Veerappa Lakshmaiah V. Source A related resource from which the described resource is derived Scientific Reports, Vol-14, No. 1 Publisher An entity responsible for making the resource available Nature Research Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1038/s41598-024-51647-x" target="_blank" rel="noreferrer noopener">https://doi.org/10.1038/s41598-024-51647-x</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182186564&amp;doi=10.1038%2Fs41598-024-51647-x&amp;partnerID=40&amp;md5=20d41756f52758aa17cb20fe48703a62" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182186564&amp;doi=10.1038%2fs41598-024-51647-x&amp;partnerID=40&amp;md5=20d41756f52758aa17cb20fe48703a62</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Relation A related resource ISSN: 20452322; PubMed ID: 38218918; LS;2023-2024; Vol-1; 0966-0978 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Thirumoorthy G., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Karnataka, Bengaluru, 560029, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Sciences, Sejong University, Seoul, South Korea; George J.A., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Karnataka, Bengaluru, 560029, India; Nizam A., Department of Chemistry, CHRIST (Deemed to be University), Hosur Rd, Karnataka, Bengaluru, 560029, India; Nagella P., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Karnataka, Bengaluru, 560029, India; Srinatha N., Department of Physics, RV Institute of Technology and Management, Bengaluru, 560 076, India; Pappuswamy M., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Karnataka, Bengaluru, 560029, India; Alanazi A.M., Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia; Meyyazhagan A., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Karnataka, Bengaluru, 560029, India; Rengasamy K.R.R., Laboratory of Natural Products and Medicinal Chemistry (LNPMC), Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai, 602105, India, Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, 2520, South Africa; Veerappa Lakshmaiah V., Department of Life Sciences, CHRIST (Deemed to be University), Hosur Rd, Karnataka, Bengaluru, 560029, India