Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Evaluating the role of soil EPS in modifying the toxicity potential of the mixture of polystyrene nanoplastics and xenoestrogen, Bisphenol A (BPA) in Allium cepa L. Subject The topic of the resource Bisphenol A: nanoplastics; Cyto-genotoxicity; EPS; Lipid peroxidation; Oxidative stress Description An account of the resource The coexistence of emerging pollutants like nanoplastics and xenoestrogen chemicals such as Bisphenol A (BPA) raises significant environmental concerns. While the individual impacts of BPA and polystyrene nanoplastics (PSNPs) on plants have been studied, their combined effects are not well understood. This study examines the interactions between eco-corona formation, physicochemical properties, and cyto-genotoxic effects of PSNPs and BPA on onion (Allium cepa) root tip cells. Eco-corona formation was induced by exposing BPA-PSNP mixtures to soil extracellular polymeric substances (EPS), and changes were analyzed using 3D-EEM, TEM, FTIR, hydrodynamic diameter, and contact angle measurements. Onion roots were treated with BPA (2.5, 5, and 10 mgL-1) combined with plain, aminated, and carboxylated PSNPs (100 mgL-1), with and without EPS interaction. Toxicity was assessed via cell viability, oxidative stress markers (superoxide radical, total ROS, hydroxyl radical), lipid peroxidation, SOD and catalase activity, mitotic index, and chromosomal abnormalities. BPA alone increased cytotoxic and genotoxic parameters in a dose-dependent manner. BPA with aminated PSNPs exhibited the highest toxicity among the pristine mixtures, revealing increased chromosomal abnormalities, oxidative stress, and cell mortality with rising BPA concentrations. In-silico experiments demonstrated the relationship between superoxide dismutase (SOD), catalase enzymes, PSNPs, BPA, and their mixtures. EPS adsorption notably reduced cyto-genotoxic effects, lipid peroxidation, and ROS levels, mitigating the toxicity of BPA-PSNP mixtures. 2024 Elsevier B.V. Creator An entity primarily responsible for making the resource Giri S.; Debroy A.; Nag A.; Mukherjee A. Source A related resource from which the described resource is derived Journal of Hazardous Materials, Vol-477 Publisher An entity responsible for making the resource available Elsevier B.V. Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.jhazmat.2024.135252" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.jhazmat.2024.135252</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199297000&amp;doi=10.1016%2Fj.jhazmat.2024.135252&amp;partnerID=40&amp;md5=02949f5f04a6fbb607819cf8334793f5" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199297000&amp;doi=10.1016%2fj.jhazmat.2024.135252&amp;partnerID=40&amp;md5=02949f5f04a6fbb607819cf8334793f5</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 3043894; PubMed ID: 39047567; CODEN: JHMAD Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Giri S., Centre for Nanobiotechnology, Vellore Institute of Technology, Tamil Nadu, Vellore, India; Debroy A., Centre for Nanobiotechnology, Vellore Institute of Technology, Tamil Nadu, Vellore, India; Nag A., Department of Life Sciences, Bangalore Central campus, CHRIST (Deemed to be University), Bangalore, India; Mukherjee A., Centre for Nanobiotechnology, Vellore Institute of Technology, Tamil Nadu, Vellore, India