Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Development of a fluorescent scaffold by utilizing quercetin template for selective detection of Hg2+: Experimental and theoretical studies along with live cell imaging Subject The topic of the resource Cell imaging; Cyclic voltammograms; DFT study; Fluorescence; Green gram; Quercetin Description An account of the resource Quercetin is an important antioxidant with high bioactivity and it has been used as SARS-CoV-2 inhibitor significantly. Quercetin, one of the most abundant flavonoids in nature, has been in the spot of numerous experimental and theoretical studies in the past decade due to its great biological and medicinal importance. But there have been limited instances of employing quercetin and its derivatives as a fluorescent framework for specific detection of various cations and anions in the chemosensing field. Therefore, we have developed a novel chemosensor based on quercetin coupled benzyl ethers (QBE) for selective detection of Hg2+ with naked-eye colorimetric and turn-on fluorometric response. Initially QBE itself exhibited very weak fluorescence with low quantum yield (? = 0.009) due to operating photoinduced electron transfer (PET) and inhibition of excited state intramolecular proton transfer (ESIPT) as well as intramolecular charge transfer (ICT) within the molecule. But in presence of Hg2+, QBE showed a sharp increase in fluorescence intensity by 18-fold at wavelength 444 nm with high quantum yield (? = 0.159) for the chelation-enhanced fluorescence (CHEF) with coordination of Hg2+, which hampers PET within the molecule. The strong binding affinity of QBE towards Hg2+ has been proved by lower detection limit at 8.47 M and high binding constant value as 2 104 M?1. The binding mechanism has been verified by DFT study, Cyclic voltammograms and Jobs plot analysis. For the practical application, the binding selectivity of QBE with Hg2+ has been capitalized in physiological medium to detect intracellular Hg2+ levels in living plant tissue by using green gram seeds. Thus, employing QBE as a fluorescent chemosensor for the specific identification of Hg2+ will pave the way for a novel approach to simplifying the creation of various chemosensors based on quercetin backbone for the precise detection of various biologically significant analytes. 2024 Elsevier B.V. Creator An entity primarily responsible for making the resource Vishnu S.; Maity S.; Maity A.C.; Kumar M.S.; Dolai M.; Nag A.; bylappa Y.; Dutta G.; Mukherjee B.; Kumar Das A. Source A related resource from which the described resource is derived Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, Vol-315 Publisher An entity responsible for making the resource available Elsevier B.V. Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.saa.2024.124249" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.saa.2024.124249</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189863505&amp;doi=10.1016%2Fj.saa.2024.124249&amp;partnerID=40&amp;md5=e721d77814a4798293a514e3a798ebd0" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85189863505&amp;doi=10.1016%2fj.saa.2024.124249&amp;partnerID=40&amp;md5=e721d77814a4798293a514e3a798ebd0</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 13861425; PubMed ID: 38603957; CODEN: SAMCA Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Vishnu S., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bangalore, 560029, India; Maity S., Sagardighi Kamada Kinkar Smriti Mahavidyalaya Sagardighi, West Bengal, Murshidabad, 742226, India; Maity A.C., Sagardighi Kamada Kinkar Smriti Mahavidyalaya Sagardighi, West Bengal, Murshidabad, 742226, India; Kumar M.S., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bangalore, 560029, India; Dolai M., Department of Chemistry, Prabhat Kumar College, Contai, W.B., Purba Medinipur, 721404, India; Nag A., Department of Life Science, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bangalore, 560029, India; bylappa Y., Department of Life Science, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bangalore, 560029, India; Dutta G., School of Medical Science and Technology (SMST), IIT Kharagpur, India; Mukherjee B., School of Medical Science and Technology (SMST), IIT Kharagpur, India; Kumar Das A., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bangalore, 560029, India