Hazard identification of endocrine-disrupting carcinogens (EDCs) in relation to cancers in humans
- Title
- Hazard identification of endocrine-disrupting carcinogens (EDCs) in relation to cancers in humans
- Creator
- Sharma N.; Kumar V.; Vimal S.; Umesh M.; Sharma P.; Thazeem B.; Kaur K.; Thomas J.; Pasrija R.; Utreja D.
- Description
- Endocrine disrupting chemicals or carcinogens have been known for decades for their endocrine signal disruption. Endocrine disrupting chemicals are a serious concern and they have been included in the top priority toxicants and persistent organic pollutants. Therefore, researchers have been working for a long time to understand their mechanisms of interaction in different human organs. Several reports are available about the carcinogen potential of these chemicals. The presented review is an endeavor to understand the hazard identification associated with endocrine disrupting carcinogens in relation to the human body. The paper discusses the major endocrine disrupting carcinogens and their potency for carcinogenesis. It discusses human exposure, route of entry, carcinogenicity and mechanisms. In addition, the paper discusses the research gaps and bottlenecks associated with the research. Moreover, it discusses the limitations associated with the analytical techniques for detection of endocrine disrupting carcinogens. 2024 Elsevier B.V.
- Source
- Environmental Toxicology and Pharmacology, Vol-109
- Date
- 2024-01-01
- Publisher
- Elsevier B.V.
- Subject
- Carcinogenesis; Carcinogens; Endocrine disruption; Hazard identification; Toxicity assessment
- Coverage
- Sharma N., Department of Biochemistry, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Thandalam, 602105, India; Kumar V., Biomaterials & Tissue Engineering (BITE) Laboratory, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Thandalam, 602105, India; Vimal S., Department of Biochemistry, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Thandalam, 602105, India; Umesh M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Sharma P., Department of Biochemistry, Maharshi Dayanand University, Haryana, Rohtak, 124001, India; Thazeem B., Waste Management Division, Integrated Rural Technology Centre (IRTC), Kerala, Palakkad, 678592, India; Kaur K., Punjab Agricultural University, Institute of Agriculture, Punjab, Gurdaspur, 143521, India; Thomas J., Department of Biotechnology, Mar Athanasius College, Kerala, India; Pasrija R., Department of Biochemistry, Maharshi Dayanand University, Haryana, Rohtak, 124001, India; Utreja D., Department of Chemistry, Punjab Agricultural University, Punjab, Ludhiana, 141004, India
- Rights
- Restricted Access
- Relation
- ISSN: 13826689; PubMed ID: 38825092; CODEN: ETOPF
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Sharma N.; Kumar V.; Vimal S.; Umesh M.; Sharma P.; Thazeem B.; Kaur K.; Thomas J.; Pasrija R.; Utreja D., “Hazard identification of endocrine-disrupting carcinogens (EDCs) in relation to cancers in humans,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 24, 2025, https://archives.christuniversity.in/items/show/12976.