Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A versatile sensor capable of ratiometric fluorescence detection of trace water and turn-on detection of Cu2+ modulating the binding interaction of a Cu(ii) complex with BSA and DNA complemented by docking studies Description An account of the resource A fluorescent molecule, pyridine-coupled bis-anthracene (PBA), has been developed for the selective fluorescence turn-on detection of Cu2+. Interestingly, the ligand PBA also exhibited a red-shifted ratiometric fluorescence response in the presence of water. Thus, a ratiometric water sensor has been utilized as a selective fluorescence turn-on sensor for Cu2+, achieving a 10-fold enhancement in the fluorescence and quantum yield at 446 nm, with a lower detection limit of 0.358 ?M and a binding constant of 1.3 106 M?1. For practical applications, sensor PBA can be used to detect Cu2+ in various types of soils like clay soil, field soil and sand. The interaction of the PBA-Cu(ii) complex with transport proteins like bovine serum albumin (BSA) and ct-DNA has been investigated through fluorescence titration experiments. Additionally, the structural optimization of PBA and the PBA-Cu(ii) complex has been demonstrated by DFT, and the interaction of the PBA-Cu(ii) complex with BSA and ct-DNA has been analyzed using theoretical docking studies. 2024 The Royal Society of Chemistry. Creator An entity primarily responsible for making the resource Vishnu S.; Nag A.; Das A.K. Source A related resource from which the described resource is derived Analytical Methods, Vol-16, No. 30, pp. 5263-5271. Publisher An entity responsible for making the resource available Royal Society of Chemistry Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1039/d4ay00675e" target="_blank" rel="noreferrer noopener">https://doi.org/10.1039/d4ay00675e</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85200423567&amp;doi=10.1039%2Fd4ay00675e&amp;partnerID=40&amp;md5=7a268ed8cd2397bd5624f68ba86208d8" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85200423567&amp;doi=10.1039%2fd4ay00675e&amp;partnerID=40&amp;md5=7a268ed8cd2397bd5624f68ba86208d8</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 17599660; PubMed ID: 39015041 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Vishnu S., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India; Nag A., Department of Life Science, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India; Das A.K., Department of Chemistry, Christ University, Hosur Road, Karnataka, Bangalore, 560029, India