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              <text>Assessment of the strength of grignard reagent for the synthesis of secondary and tertiary alcohols of terpenes using metal plate flow reactor</text>
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              <text>Allyl magnesium chloride; Carbonyl compounds; Flow process; Grignard reagent; Metal plate reactor; Terpene alcohols</text>
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              <text>The secondary and tertiary alcohols of terpenes were synthesized from aldehydes, and ketones using allyl magnesium chloride by the continuous metal flow reactor method. The flow process was conducted using metal plate reactors of 10 ml capacity in the presence of solvent mixtures, instead of large amounts of pure solvent like tetrahydrofuran. The products were isolated, and confirmed using gas chromatography and Nuclear magnetic resonance techniques respectively. Subsequently, the optimization studies were conducted to obtain mild, and economical reaction conditions, by varying the amount of allyl magnesium chloride, temperature, pressure, retention time, and flow rates. A comparison between batch processes and flow processes proved the advantages of the flow process in terms of reproducibility and product yield without the requirement of excess reagents compared to the batch process. The product yield was found to be excellent (6097 %) and reproducible at (150) gram scale through flow process. The scope of the reaction was studied by synthesizing terpene alcohols using different carbonyl compounds at optimized reaction conditions, which resulted in high product yield. This research addresses a crucial gap in terpene alcohol synthesis, offering a scalable and environmentally friendly approach with broad applicability.  2024</text>
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              <text>Kopparapu I.; Chidambaram R.R.; Binish C.J.; Vijayasankar A.V.; Chundattu S.J.; Cheedarala R.K.</text>
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              <text>Results in Engineering, Vol-22</text>
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              <text>Elsevier B.V.</text>
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              <text>2024-01-01</text>
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              <text>&lt;a href="https://doi.org/10.1016/j.rineng.2024.102183" target="_blank" rel="noreferrer noopener"&gt;https://doi.org/10.1016/j.rineng.2024.102183&lt;/a&gt;
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              <text>All Open Access; Gold Open Access</text>
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              <text>ISSN: 25901230</text>
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              <text>Kopparapu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, 560029, India; Chidambaram R.R., Supramolecular and Organometallic Chemistry Lab, Department of Inorganic Chemistry, School of Chemistry, Madurai Kamaraj University, Tamil Nadu, Madurai, 625021, India; Binish C.J., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, 560029, India; Vijayasankar A.V., Department of Science and Humanities, CHRIST (Deemed to be University), Bengaluru, 560074, India; Chundattu S.J., Department of Science and Humanities, CHRIST (Deemed to be University), Bengaluru, 560074, India; Cheedarala R.K., Research Institute of Mechatronics, Department of Mechanical Engineering, Changwon National University, Changwon City, South Korea</text>
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