A rapid and selective on-off fluorescence detection of lethal pulmonary agent phosgene supplemented with theoretical approach: a cost-effective sensing tool for household bleach and soil analysis
- Title
- A rapid and selective on-off fluorescence detection of lethal pulmonary agent phosgene supplemented with theoretical approach: a cost-effective sensing tool for household bleach and soil analysis
- Creator
- Kumar M.S.; Dolai M.; Kumar Das A.
- Description
- A fluorescent probe, 4-(di-phenylamino)-benzaldehyde oxime (DPBO), was developed comprising 4-(diphenylamino) benzaldehyde as the fluorophore and hydroxyl amine, where the resultant oxime group leads to the formation of a recognition site for the selective on-off fluorescence detection of lethal phosgene with the dimer formation of DPBO through carbonate linkage generated from phosgene. The probe DPBO also exhibits notable spectrofluorometric response in different solvents, as demonstrated by SEM analysis. The detection limit of the probe DPBO towards phosgene was calculated as 21.53 ?M, with a fast reaction response time within 30 s and the fluorescence quenching efficiency of DPBO by phosgene was measured through the Stern-Volmer quenching constant (KSV) estimated at 1.03 104 M?1. Confirmation of the sensing mechanism was achieved through various spectroscopic techniques such as UV-vis, emission spectroscopy, mass spectrometry, and computational studies. For practical applications, the sensor DPBO can be utilized for the detection of phosgene in household bleach, soil analysis and dipstick method. 2024 The Royal Society of Chemistry.
- Source
- New Journal of Chemistry, Vol-48, No. 20, pp. 9103-9109.
- Date
- 2024-01-01
- Publisher
- Royal Society of Chemistry
- Coverage
- Kumar M.S., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bangalore, 560029, India; Dolai M., Department of Chemistry, Prabhat Kumar College, Contai, W.B., Purba Medinipur, 721404, India; Kumar Das A., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Karnataka, Bangalore, 560029, India
- Rights
- Restricted Access
- Relation
- ISSN: 11440546; CODEN: NJCHE
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Kumar M.S.; Dolai M.; Kumar Das A., “A rapid and selective on-off fluorescence detection of lethal pulmonary agent phosgene supplemented with theoretical approach: a cost-effective sensing tool for household bleach and soil analysis,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 25, 2025, https://archives.christuniversity.in/items/show/13149.