Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Biocidal activities of nickel oxide nanoparticles modified by copper and manganese, synthesized by green process Subject The topic of the resource antimicrobial and anticancer properties; copper and manganese; NiO; Trigonella foenum-graecum Description An account of the resource In recent years, the development of dual dopant-based nanoparticles (NPs) has gained significant attention as they possess exceptional physico-chemical and biomedical properties, making them potential candidates for antimicrobial and anticancer uses. In this research, we successfully synthesized nickel oxide (NiO) and copper, manganese-doped NiO (CuMn:NiO) NPs using a green synthesis method. The synthesis process involved Trigonella foenum-graecum (T.f.graecum) leaves extract as a nucleating agent. The synthesized nanoparticles were confirmed by various physico-chemical studies. Based on X-ray diffraction analysis, the median size was determined as 36 nm for NiO and 32 nm for CuMn:NiO NPs. The antibacterial study revealed that CuMn:NiO NPs exhibited a higher zone of inhibition in contrast to both Gram-positive (Streptococcus pneumoniae, Bacillus subtilis, Bacillus megaterium) and Gram-negative bacteria (Klebsiella pneumoniae, Escherichia coli, Vibrio cholerae) compared with NiO NPs and commercial amoxicillin. The antifungal studies conducted against Candida albicans demonstrated that CuMn:NiO NPs exhibited enhanced efficacy in comparison to NiO NPs. In vitro testing against human breast cancer cells (MCF-7) demonstrated the anticancer potential of NiO and CuMn:NiO NPs, supported by IC50 concentrations of 11 and 9?g/mL, respectively. The photoluminescence (PL) spectra of NiO and CuMn:NiO NPs exhibited a green emission at 508 and 518 nm, respectively, which indicated the generation of active free radicals by the NPs. These findings suggest that CuMn:NiO NPs hold promise in the healthcare industry. 2024 John Wiley &amp; Sons Ltd. Creator An entity primarily responsible for making the resource Ganapathy K.; Pandey S.P.; Bishnoi S.; Suriyaprakash J.; Alarfaj A.A.; Hirad A.H.; Thangavelu I. Source A related resource from which the described resource is derived Applied Organometallic Chemistry, Vol-38, No. 4 Publisher An entity responsible for making the resource available John Wiley and Sons Ltd Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1002/aoc.7366" target="_blank" rel="noreferrer noopener">https://doi.org/10.1002/aoc.7366</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85184176604&amp;doi=10.1002%2Faoc.7366&amp;partnerID=40&amp;md5=3cbe0629b4e61ce1886b48ef75ee785e" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85184176604&amp;doi=10.1002%2faoc.7366&amp;partnerID=40&amp;md5=3cbe0629b4e61ce1886b48ef75ee785e</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 2682605; CODEN: AOCHE Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Ganapathy K., Department of Biotechnology, School of Sciences, Jain (Deemed-to-be University), Bangalore, India; Pandey S.P., Department of Physics, Teerthanker Mahaveer University, Uttar Pradesh, Moradabad, India; Bishnoi S., Department of Chemistry, Vivekananda Global University, Rajasthan, Jaipur, India; Suriyaprakash J., Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, China; Alarfaj A.A., Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia; Hirad A.H., Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India