Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Precise surface molecular engineering of 2D-Bi2S3 enables the ultrasensitive simultaneous detection of dopamine, epinephrine, serotonin and uric acid Subject The topic of the resource 2D materials; Biosensor; Dopamine; Electrochemical; Epinephrine; Serotonin; Surface engineering; Uric acid Description An account of the resource Multiple biomolecule detection at a single read is an emerging and highly desirable technology in point-of-care diagnostics. Thus, functional nanoscale materials with high precision and stability at an affordable cost are required to fabricate adaptable multiplex biosensing devices with exceptional performance. Herein, an ultrasensitive molecularly engineered 2D-Bi2S3 biosensor is developed via a two-step synthetic approach. Simultaneous detection of dopamine (DA), epinephrine (EP), serotonin (ST), and uric acid (UA) is achieved at the nanomolar level. The surface molecular engineered 2D-Bi2S3 by 4-mercaptobenzoic acid (MBA) exhibits a well crystalline nature and consists of 36 stacked layers with creased-paper-like morphology after an MBA molecule has been precisely linked at the basal plane of Bi2S3. Bi2S3-MBA's surface/vibrational spectroscopic and scanning tunneling microscopic studies demonstrate the Bi2S3-MBA electronic nature and the linked molecule present on the Bi2S3 surface with a comparatively large random distribution of MBA molecules at the basal plane than the edge plane. The density functional theory (DFT) calculation verifies the proposed molecular interaction mechanism. The success of this unique surface molecular engineering strategy, which effectively modified the electronic and surface configuration of the 2D-Bi2S3, offers an exciting possibility for building different variants of the versatile biosensor for real-world diagnostic device applications. 2024 Creator An entity primarily responsible for making the resource Suriyaprakash J.; Thangavelu I.; Huang Y.; Hu Z.; Wang H.; Zhan Y.; Wu L.; Shan L. Source A related resource from which the described resource is derived Surfaces and Interfaces, Vol-46 Publisher An entity responsible for making the resource available Elsevier B.V. Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.surfin.2024.104021" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.surfin.2024.104021</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85183955053&amp;doi=10.1016%2Fj.surfin.2024.104021&amp;partnerID=40&amp;md5=7bfc79ca43fb3260ed817ddfef1d9e99" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85183955053&amp;doi=10.1016%2fj.surfin.2024.104021&amp;partnerID=40&amp;md5=7bfc79ca43fb3260ed817ddfef1d9e99</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 24680230 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Suriyaprakash J., Guangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter, Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006, China; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Huang Y., Guangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter, Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006, China; Hu Z., Guangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter, Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006, China; Wang H., Guangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter, Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006, China; Zhan Y., Guangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter, Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006, China; Wu L., Guangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter, Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006, China; Shan L., School of Materials Science and Chemical Engineering, Harbin University of Science and Technology, Harbin, 150040, China