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Title A name given to the resource Multifunctional characteristics of biosynthesized CoFe2O4@Ag nanocomposite by photocatalytic, antibacterial and cytotoxic applications Subject The topic of the resource Antibacterial activity; Carissa carandas; Cytotoxicity; Green synthesis; Photocatalysis; Rhodamine B (RhB) Description An account of the resource Carissa carandas, a traditional medicinal herb with a high concentration of antioxidant phytochemicals, has been used for thousands of years in the Ayurveda, Unani, and homoeopathic schools of medicine. By employing Carissa carandas bark extract as a reducing and capping agent in green biosynthesis, we extend this conventional application to produce CoFe2O4 and CoFe2O4@Ag nanocomposite. A variety of techniques have been used to characterize the synthesised nanocomposite, including UVVis, FTIR, XRD, FESEM, EDX, and BET. The CoFe2O4 and CoFe2O4@Ag nanocomposite demonstrated promising antibacterial action against human bacterial pathogens like B. subtilis and S. aureus as gram positive and P. aeruginosa and E. coli as gram negative with inhibition zones of 24.3 0.57, 17.4 0.75 and 20.5 0.5, 19.8 1.6 mm respectively, and the obtained results were superior to the nanocomposite without silver. Moreover, in-vitro cytotoxicity effects of biosynthesized CoFe2O4 and CoFe2O4@Ag were performed on the human breast cancer cell MCF-7. It was found that the MCF-7 cells' 50% inhibitory concentration (IC50) was 60 ?g/mL. Additionally, biosynthesized CoFe2O4 and CoFe2O4@Ag nanocomposite was used to demonstrate the photocatalytic eradication of Rhodamine Blue (RhB). Due to the addition of Ag, which increases surface area, conductivity, and increased charge carrier separation, the CoFe2O4@Ag nanocomposite exhibits a high percentage of photocatalytic degradation of ? 98% within 35 min under UV light irradiation. The photocatalytic performance of as-synthesised nanocomposite was evaluated using dye degradation-adsorption in both natural light and dark condition. Under dark conditions, it was found that 2 mg mL?1 CoFe2O4@Ag in RhB aqueous solution (5 ppm) causes dye adsorption in 30 min with an effectiveness of 72%. Consequently, it is anticipated that the CoFe2O4@Ag nanocomposite will be a promising photocatalyst and possibly a noble material for environmental remediation applications. 2023 Elsevier Ltd Creator An entity primarily responsible for making the resource Punyasamudram S.; Puthalapattu R.P.; Bathinapatla A.; Mulpuri R.; Kanchi S.; Kumar P.V.N. Source A related resource from which the described resource is derived Chemosphere, Vol-349 Publisher An entity responsible for making the resource available Elsevier Ltd Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.chemosphere.2023.140892" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.chemosphere.2023.140892</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85179602783&amp;doi=10.1016%2Fj.chemosphere.2023.140892&amp;partnerID=40&amp;md5=064321af3e1d5130b1a1ee5ad148f97d" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85179602783&amp;doi=10.1016%2fj.chemosphere.2023.140892&amp;partnerID=40&amp;md5=064321af3e1d5130b1a1ee5ad148f97d</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 456535; PubMed ID: 38070614; CODEN: CMSHA Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Punyasamudram S., Department of Chemistry, GITAM University, Telangana, Hyderabad, 502329, India, Department of Chemistry, Sri Padmavati Mahila Visvavidyalayam, Andhra Pradesh, Tirupati, 517502, India; Puthalapattu R.P., Department of Chemistry, Institute of Aeronautical Engineering, Telangana, Hyderabad, 500043, India; Bathinapatla A., Department of Chemistry, CMR Institute of Technology, Bengaluru, 560037, India, Centre of Excellence- Sensors &amp; Nanoelectronics, CMR Institute of Technology, Bengaluru, 560037, India; Mulpuri R., Department of Chemistry, Raghu Engineering College (Autonomous), Dakamarri (v), Bheeminipatnam, Andhra Pradesh, Visakhapatnam, 531162, India; Kanchi S., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, 560 029, India; Kumar P.V.N., Department of Chemistry, GITAM University, Telangana, Hyderabad, 502329, India