Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Multivariate statistical optimization of phenolics and antioxidants from nutmeg seeds (Myristica fragrans Houtt) Subject The topic of the resource ANOVA; Antioxidant; Nutmeg; Optimization; Response surface methodology Description An account of the resource The present study aimed to optimize the phenolic and antioxidant-rich extract from the nutmeg (Myristica fragrans Houtt) by using a two-factor 26-run central composite design-based response surface methodology tool. The selected parameters were extraction period (2 to 5days), solvent-to-water ratio (v/v) (50100%), and type of solvent (acetone or ethanol). The optimized extract at conditions of 3.14days incubation and 68% (v/v) acetone showed total phenolic content (TPC), total flavonoid content (TFC), and DPPH antioxidant assay as 376.38mg GAE/g DW, 34.40mg QUE/g DW and 842.46mg AAE/g DW, respectively. Among the nineteen (19) compounds identified by the LCMS, myristicin (37.74%) was found to be the highest. Nine (9) alkane-fatty acyl compounds were determined by the GCMS analysis, as well. Additionally, SEM and XRD revealed sheet-like anatomy with the presence of Carbon (C), Oxygen (O) and Potassium (K). The study presented a unique approach to optimizing phenolic-rich antioxidant extracts from nutmeg using response surface methodology, offering valuable insights for more efficient extraction of bioactive compounds with minimal resource waste and potentially enhancing the utilization of nutmeg's nutraceutical properties. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Creator An entity primarily responsible for making the resource Chacko A.M.; Nag A. Source A related resource from which the described resource is derived Journal of Food Measurement and Characterization Publisher An entity responsible for making the resource available Springer Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1007/s11694-024-03031-6" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/s11694-024-03031-6</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85212692201&amp;doi=10.1007%2Fs11694-024-03031-6&amp;partnerID=40&amp;md5=178bf5e5012a5b0995d085bb05a36130" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85212692201&amp;doi=10.1007%2fs11694-024-03031-6&amp;partnerID=40&amp;md5=178bf5e5012a5b0995d085bb05a36130</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 21934126 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Chacko A.M., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560029, India; Nag A., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560029, India