Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Development of Biocompatible Barium peroxide/Pluronic F127/L-ornithine Composite for Enriched Antimicrobial, Antioxidant and Anticancer Potential: An in vitro Study Subject The topic of the resource Anti-oxidant; Anticancer activities; Antimicrobial; Barium peroxide; L-ornithine; Pluronic F 127 Description An account of the resource Osteosarcoma (MG-63) is a type of bone cancer affects mostly adolescents and young adults. Disease-causing microorganisms like Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae and Candida albicans pose serious illness in humans. There is a need to develop multifunctional composite to combat cancer and other most common disease caused by disease causing microorganisms. In this context, BaO2 and pluronic F127, L-Ornithine coated BaO2 (BaO2-PF127-LO) composite have been prepared and characterized by XRD, FTIR, UV-Vis, SEM, HRTEM, EDAX, and XPS analytical techniques. BaO2 and BaO2-PF127-LO were orthorhombic crystalline structure and the crystallite size was found as 32nm for BaO2 and 26nm for modified BaO2 PL studies revealed the green emission observed at 506nm for BaO2-PF127-LO composite which is absent in the case of bare BaO2. Antimicrobial activity of BaO2 and BaO2-PF127-LO was investigated. MTT assay was performed to determine the anticancer potential while the DPPH free radical scavenging assay was carried out to determine the antioxidant potential. The experiment study revealed that the BaO2-PF127-LO exhibited enhanced antimicrobial, antioxidant, and anticancer activity and low toxicity when compared to pristine BaO2. The experimental results revealed that the BaO2-PF127-LO composite holds promising potential for biomedical applications. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024. Creator An entity primarily responsible for making the resource Almaimani R.A.; Ibrahim I.A.A.; Almaimani G.; Almasmoum H.A.; Ghaith M.M.; Bamagous G.A.; Arulselvan P.; Thangavelu I. Source A related resource from which the described resource is derived Journal of Inorganic and Organometallic Polymers and Materials Publisher An entity responsible for making the resource available Springer Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1007/s10904-024-03467-9" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/s10904-024-03467-9</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85209652518&amp;doi=10.1007%2Fs10904-024-03467-9&amp;partnerID=40&amp;md5=3f32437d7c5ea8ad831640c225ac1ee4" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85209652518&amp;doi=10.1007%2fs10904-024-03467-9&amp;partnerID=40&amp;md5=3f32437d7c5ea8ad831640c225ac1ee4</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 15741443 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Almaimani R.A., Department of Biochemistry, Faculty of Medicine, Umm Al-Qura University, Al Abdeyah, Makkah, 24381, Saudi Arabia; Ibrahim I.A.A., Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, P.O.Box 13578, Al-Abidiyah, Makkah, 21955, Saudi Arabia; Almaimani G., Department of surgery, Faculty of Medicine, Umm Al-Qura University, PO Box 7607, Al Abdeyah, Makkah, Saudi Arabia; Almasmoum H.A., Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia; Ghaith M.M., Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia; Bamagous G.A., Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, P.O.Box 13578, Al-Abidiyah, Makkah, 21955, Saudi Arabia; Arulselvan P., Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 602105, India; Thangavelu I., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India