Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Efficient one-pot green synthesis of carboxymethyl cellulose/folic acid embedded ultrafine CeO2 nanocomposite and its superior multi-drug resistant antibacterial activity and anticancer activity Subject The topic of the resource Antibacterial activity; Biocompatibility; Carboxymethyl cellulose; CeO₂; Folic acid Description An account of the resource Due to the prevalence of drug-resistant bacteria and the ongoing shortage of novel antibiotics as well as the challenge of treating breast cancer, the therapeutic and clinical sectors are consistently seeking effective nanomedicines. The incorporation of metal oxide nanoparticles with biological macromolecules and an organic compound emerges as a promising strategy to enhance breast cancer treatment and antibacterial activity against drug-resistant bacteria in various biomedical applications. This study aims to synthesize a unique nanocomposite consisting of CeO2 embedded with folic acid and carboxymethyl cellulose (CFC NC) via a green precipitation method using Moringa oleifera. Various spectroscopic and microscopic analyses are utilized to decipher the physicochemical characteristics of CFC NC and active phytocompounds of Moringa oleifera. Antibacterial study against MRSA (Methicillin-resistant Staphylococcus aureus) demonstrated a higher activity (95.6%) for CFC NC compared to its counterparts. The impact is attributed to reactive oxygen species (ROS), which induces a strong photo-oxidative stress, leading to the destruction of bacteria. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of CFC NC are determined as 600g/mL and 1000g/mL, respectively. The anticancer activity against breast cancer cell resulted in the IC50 concentration of 10.8?g/mL and 8.2?g/mL for CeO2 and CFC NC respectively.The biocompatibility test was conducted against fibroblast cells and found 85% of the cells viable, with less toxicity. Therefore, the newly synthesized CFC NC has potential applications in healthcare and industry, enhancing human health conditions. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024. Creator An entity primarily responsible for making the resource Boopathi T.S.; Rajiv A.; Patel T.S.G.M.; Bareja L.; Salmen S.H.; Aljawdah H.M.; Arulselvan P.; Suriyaprakash J.; Thangavelu I. Source A related resource from which the described resource is derived Bioprocess and Biosystems Engineering Publisher An entity responsible for making the resource available Springer Science and Business Media Deutschland GmbH Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1007/s00449-024-03097-y" target="_blank" rel="noreferrer noopener">https://doi.org/10.1007/s00449-024-03097-y</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85208816933&amp;doi=10.1007%2Fs00449-024-03097-y&amp;partnerID=40&amp;md5=7ea7460edfb598b1ad3126c398bfd700" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85208816933&amp;doi=10.1007%2fs00449-024-03097-y&amp;partnerID=40&amp;md5=7ea7460edfb598b1ad3126c398bfd700</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 16157591; PubMed ID: 39503917; CODEN: BBEIB Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Boopathi T.S., Department of Chemistry, Amrita School of Physical Sciences, Amrita Vishwa Vidyapeetham, Coimbatore, 641112, India, Functional Materials Laboratory, Amrita School of Engineering, Amrita Vishwa Vidyapeetham, Coimbatore, 641112, India; Rajiv A., Department of Physics, Faculty of Sciences, JAIN (Deemed-to-Be University), Karnataka, Bangalore, 562112, India; Patel T.S.G.M., Department of Community Medicine, Parul University, Gujarat, PO Limda, Tal. Waghodia, Vadodara, 391760, India; Bareja L., Centre of Research Impact and Outcome, Chitkara University, Punjab, Rajpura, 140417, India; Salmen S.H., Department of Botany and Microbiology, College of Science, King Saud University, PO Box-2455, Riyadh, 11451, Saudi Arabia; Aljawdah H.M., Department of Zoology, College of Science, King Saud University, PO Box-2455, Riyadh, 11451, Saudi Arabia; Arulselvan P., Department of Chemistry, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Tamil Nadu, Chennai, 602 105, India; Suriyaprakash J., Guangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of Matter, Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006, China; Thangavelu I., Department of Chemistry, CHRIST (Deemed to Be University), Karnataka, Bangalore, 560029, India