Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Studies on Photophysical and Biological Activity of Newly Synthesized of 4-Methylpiperidin-4-ol Substituted Pyrazole Derivatives Subject The topic of the resource GCRD parameters; HOMO-LUMO; in-vitro and in-silico biological activity; Pyrazoles Description An account of the resource The in vitro antifungal, antibacterial, and antioxidant activities of a substituted pyrazole derivative (FHM) have been evaluated in the current work. The addition of 4-methylpiperidin-4-ol, which increases the molecules lipid solubility and speeds up absorption by increasing its rate of absorption, gives the molecule strong in vitro antifungal and antibacterial properties. Additionally, it is clear from the findings of structure-activity relationship (SAR) investigations. Additionally, the ab-intio technique was used to theoretically evaluate the photophysical characteristics of produced substances. Using the DFT-B3LYP-6-31G(d) basis set, the ground state optimization and HOMO-LUMO energy levels are computed. Global chemical reactivity and descriptive characteristics are evaluated using theoretically estimated HOMO-LUMO values, and the results demonstrate that the synthesized molecule possesses a high electrophilicity and electronegative index. Overall findings indicate that substituting a 4-methylpiperidin-4-ol substituted pyrazole derivative shows good photophysical and in vitro biological applications. 2024, HARD Publishing Company. All rights reserved. Creator An entity primarily responsible for making the resource Al-Hazmi G.H.; Marrakkur V.; Naik L.; Refat M.S. Source A related resource from which the described resource is derived Polish Journal of Environmental Studies, Vol-33, No. 5, pp. 5557-5565. Publisher An entity responsible for making the resource available HARD Publishing Company Date A point or period of time associated with an event in the lifecycle of the resource 2024-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.15244/pjoes/183707" target="_blank" rel="noreferrer noopener">https://doi.org/10.15244/pjoes/183707</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198418198&amp;doi=10.15244%2Fpjoes%2F183707&amp;partnerID=40&amp;md5=b348be0b7dbe3e2d884fa6c71c36b814" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85198418198&amp;doi=10.15244%2fpjoes%2f183707&amp;partnerID=40&amp;md5=b348be0b7dbe3e2d884fa6c71c36b814</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access Relation A related resource ISSN: 12301485 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Al-Hazmi G.H., Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia; Marrakkur V., Department of Chemistry, NMKRV College for Women, Bengaluru, 560006, India; Naik L., Department of Physics and Electronics, CHRIST (Deemed to be University), Bengaluru, 560029, India; Refat M.S., Department of Chemistry, College of Science, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia