Biogenic synthesis of dopamine/carboxymethyl cellulose/TiO2 nanoparticles using Psidium guajavaleaf extract with enhanced antimicrobial and anticancer activities
- Title
- Biogenic synthesis of dopamine/carboxymethyl cellulose/TiO2 nanoparticles using Psidium guajavaleaf extract with enhanced antimicrobial and anticancer activities
- Creator
- Ganapathy K.; Rastogi V.; Lora C.P.; Suriyaprakash J.; Alarfaj A.A.; Hirad A.H.; Indumathi T.
- Description
- The green synthesis of metal oxide nanoparticles (NPs) has garnered considerable attention from researchers due to its utilization of eco-friendly solvents during synthesis and cost-effective approaches. This study focuses on the synthesis of titanium oxide (TiO2) and dopamine (DA) carboxymethyl cellulose (CMC)-doped TiO2 (DA/CMC/TiO2) NP using Psidium guajava leaf extract, while also investigating the structural, optical, and morphological and biocidal potential of the prepared NPs. Significantly larger zones of inhibition were observed for DA/CMC/TiO2 NPs compared to TiO2 against various pathogens. Moreover, the MTT assay was carried out to evaluate the anticancer activity of the prepared samples against MG-63 cells, and the results revealed that DA/CMC/TiO2 NPs exhibited significantly higher level of anticancer activity compared to TiO2. The experimental results demonstrated that DA/CMC/TiO2 NPs exhibited enhanced anticancer activity in a dose-dependent manner when compared to TiO2 NPs. 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
- Source
- Bioprocess and Biosystems Engineering, Vol-47, No. 1, pp. 131-143.
- Date
- 2024-01-01
- Publisher
- Springer Science and Business Media Deutschland GmbH
- Subject
- Anti- fungal activity; Anti-bacterial activity; Anti-cancer; CMC; Dopamine; Psidium guajava; TiO2
- Coverage
- Ganapathy K., Department of Biotechnology, School of Sciences, Jain (Deemed-to-be University), Bangalore, 560027, India; Rastogi V., College of Pharmacy, Teerthanker Mahaveer University, Uttar Pradesh, Moradabad, 244001, India; Lora C.P., Department of Chemistry, Vivekananda Global University, Rajasthan, Jaipur, 303012, India; Suriyaprakash J., Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices, School of Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou, 510006, China; Alarfaj A.A., Department of Botany and Microbiology, College of Science, King Saud University, P. O. Box.2455, Riyadh, 11451, Saudi Arabia; Hirad A.H., Department of Botany and Microbiology, College of Science, King Saud University, P. O. Box.2455, Riyadh, 11451, Saudi Arabia; Indumathi T., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, 560029, India
- Rights
- Restricted Access
- Relation
- ISSN: 16157591; PubMed ID: 38103080; CODEN: BBEIB
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Ganapathy K.; Rastogi V.; Lora C.P.; Suriyaprakash J.; Alarfaj A.A.; Hirad A.H.; Indumathi T., “Biogenic synthesis of dopamine/carboxymethyl cellulose/TiO2 nanoparticles using Psidium guajavaleaf extract with enhanced antimicrobial and anticancer activities,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 24, 2025, https://archives.christuniversity.in/items/show/13775.