Biosynthesis of zinc oxide nanoparticles mediated by Strobilanthes hamiltoniana: Characterizations, and its biological applications
Anti-cancer; Anti-Microbial; Dye degradation; Strobilanthes hamiltoniana; Zinc oxide
Nanoparticles of Zinc oxide (ZnONPs), has a variety of applications such as antibacterial property, water treatment for pollutant removal, and as catalysts for organic reactions etc. and have been synthesized utilizing a variety of approaches, including green synthesis, chemical precipitation, solgel, hydrothermal synthesis, and microwave-assisted synthesis. In the present work, easy and economically viable ZnONPs were synthesized utilizing Strobilanthes hamiltoniana (SH) leaf extracts. Phytochemicals form S. hamiltoniana act as agents for reducing and capping the metal oxide ions. A range of analytical and microscopic techniques have been used to investigate the physical and chemical properties of ZnONPs. At 360 ?nm, green synthesized SH-ZnONPs showed robust UVVis absorption. The nanosize, shape, and crystalline structure of SH-ZnO NPs were characterized using XRD and electron microscopy techniques. Using SH-ZnO NPs, the photocatalytic activity of textile dyes such as Reactive blue 220 (RB-220), Reactive blue 222A (RB-222A), Reactive yellow 145 (RY-145) and Reactive yellow 86 (RY-86) dyes showed degradation efficiency of 97.3%, 78.57%, 88.88%, and 83.33% after 320 ?min. ZnONPs exhibited remarkable antibacterial effectiveness against bacterial and fungal pathogens using the Minimum inhibitory concentration approach. Their MIC values were calculated, and free radical scavenging experiments showed antioxidant activity. The SH-ZnONPs were validated using HepG2 (IC50) cancerous cells lines and showed promising anti-cancer activity. These results revealed that SH-ZnO NPs had promising benefits that could be utilized as a viable therapeutic candidate. 2023 The Author(s)
Gangwar J.; Balasubramanian B.; Pratap Singh A.; Meyyazhagan A.; Pappuswamy M.; Alanazi A.M.; Rengasamy K.R.R.; Kadanthottu Sebastian J.
Kuwait Journal of Science, Vol-51, No. 1
All Open Access; Gold Open Access; Green Open Access
https://doi.org/10.1016/j.kjs.2023.07.008 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85176585132&doi=10.1016%2fj.kjs.2023.07.008&partnerID=40&md5=40bf9c3a958a68784901e895c8a87c53
Gangwar J., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Gwangjin-gu, Seoul, 05006, South Korea; Pratap Singh A., Department of Materials Engineering, Indian Institute of Science, Karnataka, Bangalore, 560012, India; Meyyazhagan A., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Pappuswamy M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Alanazi A.M., Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia; Rengasamy K.R.R., Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, 2520, South Africa; Kadanthottu Sebastian J., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India