Green synthesized cobalt nanoparticles from Trianthema portulacastrum L. as a novel antimicrobials and antioxidants
Animal biotechnology; antibacterial; antifungal; antioxidant; cobalt nanoparticles; environmental biotechnology; Trianthema portulacastrum
Trianthema portulacastrum is a dietary and medicinal plant that has gained substantial importance due to its pharmacological properties. This plant was used for its various healing properties since the ancient period in ayurvedic system of medicine. The green synthesis technique is an eco-friendly as well as cost effective technique which can produce more biocompatible nanoparticles when compared with those fabricated by physio-chemical methods. Therefore, nanoparticles produced by green synthesis are credible alternatives to those which are produced by conventional synthesis techniques. This research mainly aims to produce nanoparticles with the methanolic leaf extract of T. portulacastrum. The optimized nanoparticles were further analyzed for anti-fungal, anti-bacterial and antioxidant properties. Disk diffusion assay was used for the determination of the antimicrobial property and on the other hand, DPPH radical scavenging assay as well as hydrogen peroxide scavenging activity proved the antioxidant property of the formulation. The study revealed that Escherichia coli (gram negative strain) shows greater zone of inhibition when compared with Bacillus subtilis (gram positive bacteria). The nanoparticles have also been reported to show significant anti-fungal activity against the strains of Aspergillus niger and Fusarium oxysporum which proves its desirability for its further use against both bacterial as well as fungal infections. The novel formulation can be explored dually as antimicrobial and antioxidant agent. 2023 Taylor & Francis Group, LLC.
Prakash A.; Sur S.; Dave V.; Sharma P.; Das S.; Roy P.; Hegde G.
Preparative Biochemistry and Biotechnology, Vol-54, No. 3, pp. 328-342.
ISSN: 10826068; PubMed ID: 37493403; CODEN: PBBIF
Prakash A., Department of Bio-science and Biotechnology, Banasthali Vidyapith, Rajasthan, India; Sur S., Department of Pharmaceutical Technology, School of Medical Sciences, Adamas University, Kolkata, India; Dave V., Department of Pharmacy, School of Health Science, Central University of South Bihar, Gaya, India; Sharma P., Department of Home Science, Mahila Mahavidhyala, Banaras Hindu University, India; Das S., Department of Chemistry, University of Engineering and Management, Kolkata, India; Roy P., GITAM School of Pharmacy, GITAM (Deemed to be University), Visakhapatnam, India; Hegde G., Centre for Advanced Research and Development (CARD), CHRIST (Deemed to be University), Bengaluru, India, Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India