Phytoextract-mediated synthesis of Cu doped NiO nanoparticle using cullon tomentosum plant extract with efficient antibacterial and anticancer property
- Title
- Phytoextract-mediated synthesis of Cu doped NiO nanoparticle using cullon tomentosum plant extract with efficient antibacterial and anticancer property
- Creator
- Indumathi T.; Hirad A.H.; Alarfaj A.A.; Ranjith Kumar E.; Chandrasekaran K.
- Description
- In the present study, nickel oxide (NiO) and copper-doped nickel oxide (NiCuO) nanoparticles (NPs) were successfully synthesized using Cullen tomentosum plant extract with the co-precipitation method. This work focuses on the Phyto-mediated synthesis and characterization of NPs for their biological applications. Phytochemicals that exist in the plant extract acts as reducing and capping agent. The successful formation of the NPs was validated by various analysis as XRD, FESEM, EDAX, FT-IR, UVVis, and Photoluminescence. According to XRD studies, the average crystallite size of NiO and NiCuO NPs is 36 nm and 31 nm, respectively. The river stone and nanoflower like morphology for NiO and NiCuO NPs are confirmed by FESEM image. Furthermore, the synthesized NPs were tested against Gram-positive (Bacillus subtilis, Streptococcus pneumoniae) and Gram-negative (Klebsiella pneumoniae, Escherichia coli) bacteria, which showed enhanced antibacterial activity of NiCuO NPs. The cytotoxicity of NPs was investigated against human breast cancer cells (MDA-MB-231) and fibroblast L929 cell lines. Also, the IC50 value for human breast cancer cells is 11.8 ?g/mL. According to these findings, NiCuO NPs are potential nanomaterials with advanced healthcare uses. 2023
- Source
- Ceramics International, Vol-49, No. 19, pp. 31829-31838.
- Date
- 2023-01-01
- Publisher
- Elsevier Ltd
- Subject
- Antibacterial activity; Anticancer activity; Cullon tomentosum; CuNiO NPs; Green synthesis
- Coverage
- Indumathi T., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, 560029, India; Hirad A.H., Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box, 2455, Riyadh, 11451, Saudi Arabia; Alarfaj A.A., Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box, 2455, Riyadh, 11451, Saudi Arabia; Ranjith Kumar E., Department of Physics, KPR Institute of Engineering and Technology, Tamilnadu, Coimbatore, 641 407, India; Chandrasekaran K., Department of Chemical and Biochemical Engineering, Dongguk University, Seoul, 04620, South Korea
- Rights
- Restricted Access
- Relation
- ISSN: 2728842; CODEN: CINND
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Indumathi T.; Hirad A.H.; Alarfaj A.A.; Ranjith Kumar E.; Chandrasekaran K., “Phytoextract-mediated synthesis of Cu doped NiO nanoparticle using cullon tomentosum plant extract with efficient antibacterial and anticancer property,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 27, 2025, https://archives.christuniversity.in/items/show/14059.