Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Wound healing efficacy of curcumin-loaded sandalwood bark-derived carbon nanosphere/PVA nanofiber matrix Description An account of the resource The present investigation deals with the evaluation of the wound healing efficacy of sandalwood bark-derived carbon nanospheres loaded with curcumin-embedded polyvinyl alcohol (PVA) nanofiber membranes (NF). Carbon nanospheres (CNS) were prepared by pyrolyzing sandal wood bark powder at 750 C. The morphology was confirmed by field emission scanning electron micrographs and a rich amount of carbon was confirmed by the energy dispersive X-ray technique. Curcumin, an active wound healing drug was loaded onto synthesized CNS and confirmed by ATR-IR studies. Drug-loaded CNS were anchored in a PVA matrix via electrospun nanofiber fabrication. The fabricated nanofiber membranes were characterized and evaluated for wound healing efficiency. The cytotoxicity assay proved the non-toxic nature of the prepared PVA/CNS-curcumin-loaded NF. Membranes with active CNS/drug showed better antimicrobial activity against S. aureus and E. coli, which was estimated using the zone of inhibition (ZOI) test. The in vitro scratch wound healing assay of prepared PVA/CNS-curcumin nanofibers was efficient enough and showed 92 to 98% wound closure, which was greater than the control (without drug) nanofiber membranes. The PVA nanofiber matrix with interconnected structure and carbon nanostructures together enhanced the wound healing efficacy of the considered wound healing membrane, which is a promising novel approach for future wound healing patches. 2023 The Royal Society of Chemistry. Creator An entity primarily responsible for making the resource Roopesh M.; Davis D.; Jyothi M.S.; Vandana M.; Thippeswamy B.S.; Hegde G.; Vinod T.P.; Keri R.S. Source A related resource from which the described resource is derived RSC Advances, Vol-13, No. 35, pp. 24320-24330. Publisher An entity responsible for making the resource available Royal Society of Chemistry Date A point or period of time associated with an event in the lifecycle of the resource 2023-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1039/d3ra04181f" target="_blank" rel="noreferrer noopener">https://doi.org/10.1039/d3ra04181f</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85171022873&amp;doi=10.1039%2Fd3ra04181f&amp;partnerID=40&amp;md5=62e41cef2598b4703da8f1e865a0a94b" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85171022873&amp;doi=10.1039%2fd3ra04181f&amp;partnerID=40&amp;md5=62e41cef2598b4703da8f1e865a0a94b</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Relation A related resource ISSN: 20462069; CODEN: RSCAC Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Roopesh M., Organic and Medicinal Chemistry Laboratory, Centre for Nano and Material Sciences, Jain (Deemed-to-be University), Jain Global Campus, Kanakapura, Jakkasandra Post, Kanakapura Road, Ramanagara District, Karnataka, Bangalore, 562112, India; Davis D., Department of Chemistry, CHRIST (Deemed to be University), Bhavani Nagar, Hosur Road, Bengaluru, 560029, India; Jyothi M.S., Department of Chemistry, AMC Engineering College, Bannerughatta Main Road, Bengaluru, 560083, India; Vandana M., Department of Chemistry, CHRIST (Deemed to be University), Bhavani Nagar, Hosur Road, Bengaluru, 560029, India; Thippeswamy B.S., Department of Biomedical Science, College of Pharmacy, Shaqra University, Al-Dawadmi Campus, Saudi Arabia; Hegde G., Centre for Advanced Research and Development (CARD), CHRIST (Deemed to be University), Bhavani Nagar, Hosur Road, Bengaluru, 560029, India; Vinod T.P., Department of Chemistry, CHRIST (Deemed to be University), Bhavani Nagar, Hosur Road, Bengaluru, 560029, India; Keri R.S., Organic and Medicinal Chemistry Laboratory, Centre for Nano and Material Sciences, Jain (Deemed-to-be University), Jain Global Campus, Kanakapura, Jakkasandra Post, Kanakapura Road, Ramanagara District, Karnataka, Bangalore, 562112, India