One-Pot Synthesis of Silver Nanoparticles from Garcinia gummi-gutta: Characterisation, Antimicrobial, Antioxidant, Anti-Cancerous and Photocatalytic Applications
- Title
- One-Pot Synthesis of Silver Nanoparticles from Garcinia gummi-gutta: Characterisation, Antimicrobial, Antioxidant, Anti-Cancerous and Photocatalytic Applications
- Creator
- Kurian J.T.; Balasubramanian B.; Meyyazhagan A.; Pappuswamy M.; Alanazi A.M.; Rengasamy K.R.R.; Arumugam V.A.; Sebastian J.K.; Chen J.-T.
- Description
- Background: Methods like the bio-synthesis of silver nanoparticles (Ag NPs) using plant extracts have become promising due to their eco-friendly approach. The study aimed to examine the utilization of Garcinia gummi-gutta fruit phytochemicals as agents in the biosynthesis of Ag NPs, evaluation of the antimicrobial, antioxidant, and anti-cancerous properties, as well as the photocatalytic ability of bio-synthesized Ag NPs against Crystal Violet (CV), a triphenylmethane dye. Methods: The characterization of the physical properties of the Ag NPs synthesized via the green route was done using UVVis spectrophotometry (UVVis), X-ray Diffraction (XRD), Fourier Transform Infrared Spectrophotometry (FTIR), Scanning Electron Microscopy (SEM), Zeta potential analysis, and Transmission Electron Microscopy (TEM). The dye degradation efficiency of CV was determined using synthesized Ag NPs under UV light by analyzing the absorption maximum at 579 nm. The antimicrobial efficacy of Ag NPs against E. coli, S. aureus, Candida tropicalis, and Candida albicans was examined using the broth dilution method. The antioxidant and anti-cancer properties of the synthesized Ag NPs were assessed using the DPPH and MTT assays. Results: The UV analysis revealed that the peak of synthesized Ag NPs was 442 nm. Data from FTIR, XRD, Zeta potential, SEM, and TEM analysis confirmed the formation of nanoparticles. The SEM and TEM analysis identified the presence of spherical nanoparticles with an average size of 29.12 nm and 24.18 nm, respectively. Maximum dye degradation efficiency of CV was observed at 90.08% after 320 min without any silver leaching, confirming the photocatalytic activity of Ag NPs. The bio-efficiency of the treatment was assessed using the Allium cepa root growth inhibition test, toxicity analysis on Vigna radiata, and Brine shrimp lethality assay. Conclusions: The findings revealed the environmentally friendly nature of green Ag NPs over physical/chemically synthesized Ag NPs. The synthesized Ag NPs can effectively be used in biomedical and photocatalytic applications. Copyright: 2023 The Author(s).
- Source
- Frontiers in Bioscience - Landmark, Vol-28, No. 8
- Date
- 2023-01-01
- Publisher
- IMR Press Limited
- Subject
- anti-cancer; antimicrobial activity; antioxidant; crystal violet; Garcinia gummi-gutta; photocatalytic degradation; phytotoxicity
- Coverage
- Kurian J.T., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, South Korea; Meyyazhagan A., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Pappuswamy M., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Alanazi A.M., Pharmaceutical Biotechnology Laboratory, Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia; Rengasamy K.R.R., Laboratory of Natural Products and Medicinal Chemistry (LNPMC), Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, 600077, India; Arumugam V.A., Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, 641 046, India; Sebastian J.K., Department of Life Sciences, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Chen J.-T., Department of Life Sciences, National University of Kaohsiung, Kaohsiung, 811, Taiwan
- Rights
- All Open Access; Gold Open Access
- Relation
- ISSN: 27686701; PubMed ID: 37664941
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Kurian J.T.; Balasubramanian B.; Meyyazhagan A.; Pappuswamy M.; Alanazi A.M.; Rengasamy K.R.R.; Arumugam V.A.; Sebastian J.K.; Chen J.-T., “One-Pot Synthesis of Silver Nanoparticles from Garcinia gummi-gutta: Characterisation, Antimicrobial, Antioxidant, Anti-Cancerous and Photocatalytic Applications,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 24, 2025, https://archives.christuniversity.in/items/show/14106.