Genotoxic repercussion of high-intensity radiation (x-rays) on hospital radiographers
- Title
- Genotoxic repercussion of high-intensity radiation (x-rays) on hospital radiographers
- Creator
- Kuchi Bhotla H.; Balasubramanian B.; Rengasamy K.R.R.; Arumugam V.A.; Alagamuthu K.K.; Chithravel V.; Chaudhary A.; Alanazi A.M.; Pappuswamy M.; Meyyazhagan A.
- Description
- Recent technological advances in the medical field have increased the plausibility of exposing humans to high-intensity wavelength radiations like x-rays and gamma rays while diagnosing or treating specific medical maladies. These radiations induce nucleotide changes and chromosomal alterations in the exposed population, intentionally or accidentally. A radiological investigation is regularly used in identifying the disease, especially by the technicians working in intensive care units. The current study observes the genetic damages like chromosomal abnormalities (CA) in clinicians who are occupationally exposed to high-intensity radiations (x-rays) at their workplaces using universal cytogenetic tools like micronucleus assay (MN), sister chromatid exchange and comet assay. The study was conducted between 100 exposed practitioners from the abdominal scanning, chest scanning, cranial and orthopedic or bone scanning department and age-matched healthy controls. We observed a slightly higher rate of MN and CA (p <.05) in orthopedic and chest department practitioners than in other departments concerning increasing age and duration of exposure at work. Our results emphasize taking extra precautionary measures in clinical and hospital radiation laboratories to protect the practitioners. 2022 The Authors. Environmental and Molecular Mutagenesis published by Wiley Periodicals LLC on behalf of Environmental Mutagen Society.
- Source
- Environmental and Molecular Mutagenesis, Vol-64, No. 2, pp. 123-131.
- Date
- 2023-01-01
- Publisher
- John Wiley and Sons Inc
- Subject
- chromosomal abnormalities; DNA damage; dosimetry; ionizing radiation; micronucleus; sister chromatid exchange; x-ray technicians
- Coverage
- Kuchi Bhotla H., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, India; Balasubramanian B., Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, South Korea; Rengasamy K.R.R., Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa, Laboratory of Natural Products and Medicinal Chemistry (LNPMC), Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India; Arumugam V.A., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Tamil Nadu, Coimbatore, India; Alagamuthu K.K., Department of Biotechnology, Selvamm Arts and Science College (Autonomous), Tamil Nadu, Namakkal, India; Chithravel V., Department of Cosmeceutics, China Medical University, Taichung City, Taiwan; Chaudhary A., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, India; Alanazi A.M., Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; Pappuswamy M., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, India; Meyyazhagan A., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, India
- Rights
- All Open Access; Hybrid Gold Open Access
- Relation
- ISSN: 8936692; PubMed ID: 36541415; CODEN: EMMUE
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Kuchi Bhotla H.; Balasubramanian B.; Rengasamy K.R.R.; Arumugam V.A.; Alagamuthu K.K.; Chithravel V.; Chaudhary A.; Alanazi A.M.; Pappuswamy M.; Meyyazhagan A., “Genotoxic repercussion of high-intensity radiation (x-rays) on hospital radiographers,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 26, 2025, https://archives.christuniversity.in/items/show/14405.