Heteroatom engineered graphene-based electrochemical assay for the quantification of high-risk abused drug oxytocin in edibles and biological samples
- Title
- Heteroatom engineered graphene-based electrochemical assay for the quantification of high-risk abused drug oxytocin in edibles and biological samples
- Creator
- Thomas R.; Balachandran M.
- Description
- The naive detection of scheduled H drug oxytocin is a vital requisite, owing to its deleterious impact on societal affluence prompted by unconstrained usage. Therefore, a reliable, cost-effective, and quick-to-respond analytic technique for this drug is in ample demand. In this work, we report electrochemical detection of oxytocin employing novel nitrogen, phosphorus co-doped coke-derived graphene (NPG) modified electrode. The electro-oxidation behavior of oxytocin was investigated on the NPG modified electrode by square wave stripping voltammetry (SWSV) in 0.1 M phosphate buffer of pH 7. The oxidation peak current was linear in two ranges, spanning from 0.1 nM to 10 nM and 15 nM to 95 nM. The limit of detection at the NPG electrode was calculated to be 40 pM. The practical application of developed sensor for the determination of oxytocin was examined in edible products and body fluids, hence signifying the possibility of having real-time surveillance over its misusage. 2022 Elsevier Ltd
- Source
- Food Chemistry, Vol-400
- Date
- 2023-01-01
- Publisher
- Elsevier Ltd
- Subject
- Co-doping; Electro-oxidation; Heteroatom; Oxytocin; Synergistic effect
- Coverage
- Thomas R., Materials Science Research Laboratory, Department of Physics and Electronics, Christ University, Karnataka, Bengaluru, 560029, India; Balachandran M., Materials Science Research Laboratory, Department of Physics and Electronics, Christ University, Karnataka, Bengaluru, 560029, India
- Rights
- Restricted Access
- Relation
- ISSN: 3088146; PubMed ID: 36084601; CODEN: FOCHD
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Thomas R.; Balachandran M., “Heteroatom engineered graphene-based electrochemical assay for the quantification of high-risk abused drug oxytocin in edibles and biological samples,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 25, 2025, https://archives.christuniversity.in/items/show/14431.