Synthesis of 4H-3,1-Benzothiazin-4-Ones via C-N/C-S Bond Forming Reactions
- Title
- Synthesis of 4H-3,1-Benzothiazin-4-Ones via C-N/C-S Bond Forming Reactions
- Creator
- Rama Kishore Putta V.P.; Polina S.; Gujjarappa R.; Kishore P.S.; Malakar C.C.; Pujar P.P.
- Description
- A Phosphine-free and effective process has been expressed for the formulation of N,S-heterocycles following a C-N/C-S bond forming reactions. The described process operates through EDC-HCl-mediated heterocyclization of diverse isothiocyanates and bis-nucleophiles to deliver 1,3-thiazinone derivatives, which eliminates the use of hazardous reagents. The developed protocol was found applicable over a wide range of substrates in delivering N,S-heterocycles in excellent yields at room temperature and short reaction time. 2022 Taylor & Francis Group, LLC.
- Source
- Polycyclic Aromatic Compounds, Vol-43, No. 8, pp. 7416-7425.
- Date
- 2023-01-01
- Publisher
- Taylor and Francis Ltd.
- Subject
- Benzothiazin-4-ones; C-N/C-S bond formation; coupling reagents; isothiocyanates; N,S-heterocycles
- Coverage
- Rama Kishore Putta V.P., Department of Chemistry, CHRIST (Deemed to Be University), Bangalore, India; Polina S., Department of Chemistry, CHRIST (Deemed to Be University), Bangalore, India; Gujjarappa R., Department of Chemistry, National Institute of Technology Manipur, Langol, India; Kishore P.S., Department of Chemistry, CHRIST (Deemed to Be University), Bangalore, India; Malakar C.C., Department of Chemistry, National Institute of Technology Manipur, Langol, India; Pujar P.P., Department of Chemistry, CHRIST (Deemed to Be University), Bangalore, India
- Rights
- Restricted Access
- Relation
- ISSN: 10406638
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Rama Kishore Putta V.P.; Polina S.; Gujjarappa R.; Kishore P.S.; Malakar C.C.; Pujar P.P., “Synthesis of 4H-3,1-Benzothiazin-4-Ones via C-N/C-S Bond Forming Reactions,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 26, 2025, https://archives.christuniversity.in/items/show/14684.