Phenolic composition and antioxidant potential of Cosmostigma cordatum

Title

Phenolic composition and antioxidant potential of Cosmostigma cordatum

Creator

Das A.; Mishra M.; Jaison J.P.; Sebastian J.K.

Description

Cosmostigma cordatum (Poir.) M.R. Almeida, a plant belonging to the family Apocynaceae, has not been explored for its phytochemistry and antioxidant properties. Dried samples of leaves were used to estimate the proximate and mineral composition. Distilled water, methanol, and ethanol extracts were analyzed for the quantification of phenolic compounds and antioxidant potential. EC50 values were determined to estimate the antioxidant potential. Leaves of C. cordatum were found to be a good source of proximate contents and minerals. The total phenols, flavonoids, minerals, and antioxidant activity were determined from methanolic, ethanolic, and aqueous extracts of leaves. Extracts showed a higher concentration of phenols (2.29 0.06 mg GAE g-1) in methanolic extracts and these extracts had higher antioxidant activity when compared to ethanol and aqueous extracts. The flavonoid content was higher in ethanolic extracts (51.94 0.89 mg QE g-1) than in other extracts. In addition, gas chromatography-mass spectroscopy analysis of the hexane extract of leaves identified (E,E)-7,11,15-trimethyl-3-methylene-hexadeca-1,6,10,14-tetraene, 1H-cycloprop[e]azulene, decahydro-1,1,7-trimethyl-4-methylene-, n-hexadecanoic acid, 1-naphthalenepropanol,.alpha-ethenyldecahydro-2-hydroxy-.alpha.2,5,5,8a-pentamethyl [1R[1.alpha.(R*).beta.4a.beta.8a.alpha.]]-,cis-3,14-clerodadien-13-ol, squalene and octacosane. Our results suggest that the leaves can become a potential source of food supplements, nutraceuticals, and photo-therapeutics. 2022, Indian journals. All rights reserved.

Source

Medicinal Plants, Vol-14, No. 4, pp. 597-603.

Date

2022-01-01

Publisher

Indian journals

Subject

antioxidant activity; Cosmostigma; DPPH; minerals; phenolic compounds

Coverage

Das A., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560029, India; Mishra M., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560029, India; Jaison J.P., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560029, India; Sebastian J.K., Department of Life Sciences, Christ University, Karnataka, Bangalore, 560029, India

Rights

Restricted Access

Relation

ISSN: 9754261

Format

Online

Language

English

Type

Article

Identifier

https://doi.org/10.5958/0975-6892.2022.00065.X

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85143488655&doi=10.5958%2f0975-6892.2022.00065.X&partnerID=40&md5=5d65b5aab0c23c27e59a74200993afef