QSPR ANALYSIS OF CERTAIN ANTI-HIV DRUGS

Title

QSPR ANALYSIS OF CERTAIN ANTI-HIV DRUGS

Creator

Sarkar I.; Nanjappa M.

Description

A broad spectrum of advanced medications appears yearly following the accelerated evolution of the chemical and pharmaceutical industry. In this paper, various degree-based and neighborhood degree sum-based topological indices of some anti-HIV drugs are explored applying the M-polynomial and NM-polynomial formulations. Moreover, QSPR analysis is carried out for the topological indices with regard to the physico-chemical properties of the anti-HIV drugs. The activity of nucleoside and non-nucleoside reverse transcriptase inhibitors is implemented as in drug configuration to manifest the significance of topological indices in the medicinal world. The procured outcomes affirm that topological indices being stud- ied reflect effective correlation in accordance to physical and chemical properties of the anti-HIV drugs and consequently can assist in development of advanced and promising pharmaceutical for HIV medication. 2022, RAMANUJAN SOCIETY OF MATHEMATICS AND MATHEMATICAL SCIENCES. All rights reserved.

Source

South East Asian Journal of Mathematics and Mathematical Sciences, Vol-18, No. 3, pp. 283-306.

Date

2022-01-01

Publisher

RAMANUJAN SOCIETY OF MATHEMATICS AND MATHEMATICAL SCIENCES

Subject

Anti-HIV drug; M-Polynomial; NMPolynomial; QSPR; Topological Index

Coverage

Sarkar I., Department of Mathematics, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Nanjappa M., School of Engineering and Technology, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560074, India

Rights

All Open Access; Bronze Open Access

Relation

ISSN: 9727752

Format

Online

Language

English

Type

Article

Identifier

https://doi.org/10.56827/SEAJMMS.2022.1803.24

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85165266160&doi=10.56827%2fSEAJMMS.2022.1803.24&partnerID=40&md5=106cb83533e4380bd66059ac61628dd1