Synthetic Applications of Prins Cyclization in Natural Product Syntheses
- Title
- Synthetic Applications of Prins Cyclization in Natural Product Syntheses
- Creator
- Tadiparthi K.; Roy A.; Sakirolla R.; Subba Reddy B.V.; Singh Yadav J.
- Description
- The natural products having tetrahydropyran unit with multiple chiral centers serve as magnificent building blocks for various active pharmaceutical ingredients (APIs). Prins cyclization is one of the wonderful strategies to construct tetrahydropyran unit stereoselectively in asymmetric synthesis. In this account, we discuss our research efforts toward the synthesis of various natural products from the past two decades (20052020) by using Prins cyclization as a key step. Further, the synthetic utility of this reaction was investigated and well demonstrated on various molecules successfully. 2022 The Chemical Society of Japan & Wiley-VCH GmbH.
- Source
- Chemical Record, Vol-22, No. 8
- Date
- 2022-01-01
- Publisher
- John Wiley and Sons Inc
- Subject
- Chiral pool; Natural products; Prins reaction; Tetrahyropyran; Total synthesis
- Coverage
- Tadiparthi K., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bangalore, 560029, India; Roy A., Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bangalore, 560029, India; Sakirolla R., Department of Chemistry, Central University of Karnataka, Karnataka, Gulbarga, 585367, India, Fluoro & Agrochemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India; Subba Reddy B.V., Fluoro & Agrochemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India; Singh Yadav J., Fluoro & Agrochemicals, CSIR-Indian Institute of Chemical Technology, Hyderabad, 500007, India, School of Science, Indrashil University, Gujarat, Kadi, Mehsana, 382740, India
- Rights
- Restricted Access
- Relation
- ISSN: 15278999; PubMed ID: 35532222; CODEN: CRHEA
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Tadiparthi K.; Roy A.; Sakirolla R.; Subba Reddy B.V.; Singh Yadav J., “Synthetic Applications of Prins Cyclization in Natural Product Syntheses,” CHRIST (Deemed To Be University) Institutional Repository, accessed March 1, 2025, https://archives.christuniversity.in/items/show/14947.