An Efficient Inclusion Complex Based Fluorescent Sensor for Mercury (II) and its Application in Live-Cell Imaging
- Title
- An Efficient Inclusion Complex Based Fluorescent Sensor for Mercury (II) and its Application in Live-Cell Imaging
- Creator
- Keerthana P.; Abbo H.; Cherian A.R.; Titinchi S.; Varghese A.
- Description
- The formation of an inclusion complex between hydroxypropyl-?-cyclodextrin (H-CD) and 4-acetylphenyl-4-(((6-chlorobenzo[d]thiazol-2-yl)-imino)-methyl)-benzoate (L) was investigated by FT-IR, 1H-NMR, X-ray diffraction (XRD), FT-Raman, scanning electron microscope (SEM) techniques in the solid-state, absorption and emission spectroscopy in the liquid state and the virtual state as molecular docking technique. The binding properties of the inclusion complex (H-CD: L) with cations in deionized water was observed via absorbance and photoluminescence (PL) emission spectroscopy. The fluorescence probe (H-CD: L) inclusion complex (IC) was examined for several heavy metal cations, and identified that the PL emission wavelength of the complex displayed a continuous rise in the fluorescence intensity for Hg2+. A linearity range of 1 108 11 108M and limit of detection value of 2.71 1010M was found to be achieved for the detection of Hg2+. This outcome proves that the inclusion complex H-CD: L would be a promising material for the development a solid-state fluorescence probe for detecting Hg2+. It also shows application in real sample analysis and cell imaging. 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
- Source
- Journal of Fluorescence, Vol-32, No. 3, pp. 1109-1124.
- Date
- 2022-01-01
- Publisher
- Springer
- Subject
- Chemosensor; Colorimetric; Fluorescence enhancement; Hg2+; Hydroxypropyl-beta-cyclodextrin (H-CD); Inclusion complex
- Coverage
- Keerthana P., Department of Chemistry, CHRIST (Deemed To Be University), Hosur Road, Bengaluru, 560029, India; Abbo H., Department of Chemistry, University of the Western Cape, Cape Town, South Africa, Department of Chemistry, College of Science, University of Basrah, Basrah, Iraq; Cherian A.R., Department of Chemistry, CHRIST (Deemed To Be University), Hosur Road, Bengaluru, 560029, India; Titinchi S., Department of Chemistry, University of the Western Cape, Cape Town, South Africa; Varghese A., Department of Chemistry, CHRIST (Deemed To Be University), Hosur Road, Bengaluru, 560029, India
- Rights
- Restricted Access
- Relation
- ISSN: 10530509; PubMed ID: 35305207; CODEN: JOFLE
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Keerthana P.; Abbo H.; Cherian A.R.; Titinchi S.; Varghese A., “An Efficient Inclusion Complex Based Fluorescent Sensor for Mercury (II) and its Application in Live-Cell Imaging,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 23, 2025, https://archives.christuniversity.in/items/show/15121.