Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Enzyme based bioelectrocatalysis over laccase immobilized poly-thiophene supported carbon fiber paper for the oxidation of D-ribofuranose to D-ribonolactone Subject The topic of the resource D-ribonolactone; Electrocatalysis; Laccase; Oxidation; TEMPO Description An account of the resource A modified electrode based on laccase immobilized poly-thiophene-3-carboxylic acid supported on carbon fiber paper was developed for the electrocatalytic oxidation of D-ribofuranose to otherwise difficult-to-access D-ribonolactone, a precursor for C-nucleoside based drug like Remdesivir. The electrochemical oxidation of D-ribofuranose was achieved by the TEMPO-mediated electrochemical process. The experimental parameters were optimized and validated using Design of Experiment (DoE) statistical tool indicating the concentration of TEMPO and stirring as important parameters in bulk electrolysis. The mechanism for the electrochemical oxidation of D-ribofuronose followed single electron anodic oxidation of TEMPO mediated by laccase to the corresponding oxoammonium nitrosonium species which was vital for the mediated electrochemical oxidation. The mechanism for the electrochemical oxidation was established using cyclic voltammetry and computational studies. The plausible interactions of laccase enzyme with TEMPO mediator were studied using molecular docking experiments. This facile method was successfully applied for the oxidation of D-ribofuranose to D-ribonolactone. 2022 Creator An entity primarily responsible for making the resource Thadathil D.A.; Varghese A.; Ahamed C.V.S.; Krishnakumar K.A.; Varma S.S.; Lankalapalli R.S.; Radhakrishnan K.V. Source A related resource from which the described resource is derived Molecular Catalysis, Vol-524 Publisher An entity responsible for making the resource available Elsevier B.V. Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.1016/j.mcat.2022.112314" target="_blank" rel="noreferrer noopener">https://doi.org/10.1016/j.mcat.2022.112314</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85129215512&amp;doi=10.1016%2Fj.mcat.2022.112314&amp;partnerID=40&amp;md5=124497afadfc90b02703073c7daab9d8" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85129215512&amp;doi=10.1016%2fj.mcat.2022.112314&amp;partnerID=40&amp;md5=124497afadfc90b02703073c7daab9d8</a> Rights Information about rights held in and over the resource Restricted Access Relation A related resource ISSN: 24688231; CODEN: MCOAD Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Thadathil D.A., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Varghese A., Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bangalore, 560029, India; Ahamed C.V.S., Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, 695019, India; Krishnakumar K.A., Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, 695019, India; Varma S.S., Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, 695019, India; Lankalapalli R.S., Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, 695019, India; Radhakrishnan K.V., Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, 695019, India