Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Toxicological Profiling of Onion-Peel-Derived Mesoporous Carbon Nanospheres Using In Vivo Drosophila melanogaster Model Subject The topic of the resource Acetylcholine; Carbon nanospheres; Drosophila; Nanotoxicity; Total antioxidant capacity (TAC) Description An account of the resource Toxicological profiling of the novel carbon materials has become imperative, owing to their wide applicability and potential health risks on exposure. In the current study, the toxicity of mesoporous carbon nanospheres synthesized from waste onion peel was investigated using the genetic animal model Drosophila melanogaster. The survival assays at different doses of carbon nanoparticles suggested their non-toxic effect for exposure for 25 days. Developmental and behavioral defects were not observed. The biochemical and metabolic parameters, such as total antioxidant capacity (TAC), protein level, triglyceride level, and glucose, were not significantly altered. The neurological toxicity as analyzed using acetylcholinesterase activity was also not altered significantly. Survival, behavior, and biochemical assays suggested that oral feeding of mesoporous carbon nanoparticles for 25 days did not elicit any significant toxicity effect in Drosophila melanogaster. Thus, mesoporous carbon nanoparticles synthesized from waste onion peel can be used as beneficial drug carriers in different disease models. 2022 by the authors. Licensee MDPI, Basel, Switzerland. Creator An entity primarily responsible for making the resource Bhat V.S.; Kudva A.K.; Naik H.V.; Reshmi G.; Raghu S.V.; De Padova P.; Hegde G. Source A related resource from which the described resource is derived Applied Sciences (Switzerland), Vol-12, No. 3 Publisher An entity responsible for making the resource available MDPI Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.3390/app12031528" target="_blank" rel="noreferrer noopener">https://doi.org/10.3390/app12031528</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123791156&amp;doi=10.3390%2Fapp12031528&amp;partnerID=40&amp;md5=d4ead17d8f48bebbd3d942c6c5e3c243" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123791156&amp;doi=10.3390%2fapp12031528&amp;partnerID=40&amp;md5=d4ead17d8f48bebbd3d942c6c5e3c243</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Relation A related resource ISSN: 20763417 Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Bhat V.S., Centre for Nano-Materials &amp; Displays (CND), B.M.S. College of Engineering, Bull Temple Road, Karnataka, Bengaluru, 560019, India, Department of Materials Science, Mangalore University, Mangalagangothri, Karnataka, 574199, India; Kudva A.K., Department of Biochemistry, Mangalore University, Mangalagangothri, Karnataka, 574199, India; Naik H.V., Neurogenetics Lab, Department of Applied Zoology, Mangalore University, Mangalagangothri, Karnataka, 574199, India; Reshmi G., Neurogenetics Lab, Department of Applied Zoology, Mangalore University, Mangalagangothri, Karnataka, 574199, India; Raghu S.V., Neurogenetics Lab, Department of Applied Zoology, Mangalore University, Mangalagangothri, Karnataka, 574199, India; De Padova P., Consiglio Nazionale delle Ricerche-ISM, Via Fosso del Cavaliere 100, Roma, 00133, Italy, INFN-LNF, Via Enrico Fermi 54, Frascati, 00044, Italy; Hegde G., Centre for Advanced Research and Development (CARD), CHRIST (Deemed to be University), Hosur Rd, Bhavani Nagar, S.G. Palya, Karnataka, Bengaluru, 560029, India, Department of Chemistry, CHRIST (Deemed to be University), Hosur Rd, Bhavani Nagar, S.G. Palya, Karnataka, Bengaluru, 560029, India