Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Articles Article Faculty Publications -Articles Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Anti-inflammatory activity of Sabicea brevipes Wernharm (Rubiaceae) Subject The topic of the resource anti-inflammatory; carrageenan; paw edema; phytochemicals; Sabicea brevipes Description An account of the resource Over the years, medicinal plants have been employed in the treatment of inflammation and related ailments. This study evaluated the anti-inflammatory potential of the aerial parts of S. brevipes. The extracts and fractions were further evaluated for anti-inflammatory activity in carrageenan-induced rat model at varying doses (200 and 400 mg/kg doses, orally) for 5 h of treatment. The result of the phytochemical screening showed the presence of alkaloids, terpenoids, glycosides, flavonoids and tannins in the aerial parts of the plant. The in vivo anti-inflammatory study exhibited inhibition of 42% and 44%, 47% and 36%, 33% and 31%, and 43% and 42% for methanol extract n-hexane fraction, ethyl acetate fraction, and methanol fraction, at 200 and 400 mg/kg doses, respectively. The positive control (diclofenac sodium) showed an inhibition value of 51% at 5 mg/kg dose. Finally, it is concluded that S. brevipes possesses anti-inflammatory potential which validates the enthnomedicinal claim of the plant. 2022. Attah EI et al. All Rights Reserved. Creator An entity primarily responsible for making the resource Attah E.I.; Ugwuagbo S.C.; Chinnam S.; Eze F.I.; Nnadi C.O.; Agbo M.O.; Obonga W.; Rudrapal M.; Walode S.G.; Nizam A.; Sahoo R.K.; Bendale A.R.; Khairnar S.J.; Jagtap M.R. Source A related resource from which the described resource is derived Pharmacia, Vol-69, No. 2, pp. 311-317. Publisher An entity responsible for making the resource available Pensoft Publishers Date A point or period of time associated with an event in the lifecycle of the resource 2022-01-01 Identifier An unambiguous reference to the resource within a given context <a href="https://doi.org/10.3897/pharmacia.69.e82311" target="_blank" rel="noreferrer noopener">https://doi.org/10.3897/pharmacia.69.e82311</a> <br /><br /><a href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85129632633&amp;doi=10.3897%2Fpharmacia.69.e82311&amp;partnerID=40&amp;md5=ce2f0568d29c8a9f910b836ef7471102" target="_blank" rel="noreferrer noopener">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85129632633&amp;doi=10.3897%2fpharmacia.69.e82311&amp;partnerID=40&amp;md5=ce2f0568d29c8a9f910b836ef7471102</a> Rights Information about rights held in and over the resource All Open Access; Gold Open Access; Green Open Access Relation A related resource ISSN: 4280296; CODEN: FMTYA Format The file format, physical medium, or dimensions of the resource Online Language A language of the resource English Type The nature or genre of the resource Article Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Attah E.I., 1 Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Nigeria; Ugwuagbo S.C., 1 Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Nigeria; Chinnam S., 2 Department of Chemistry, M. S. Ramaiah Institute of Technology, Affiliated to Visvesvaraya Technological University, Karnataka, Bengaluru, 560054, India; Eze F.I., 1 Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Nigeria; Nnadi C.O., 1 Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Nigeria; Agbo M.O., 1 Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Nigeria; Obonga W., 1 Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, 410001, Nigeria; Rudrapal M., 3 Department of Pharmaceutical Chemistry, Rasiklal M. Dhariwal Institute of Pharmaceutical Education and Research, Maharashtra, Pune, 411019, India; Walode S.G., 3 Department of Pharmaceutical Chemistry, Rasiklal M. Dhariwal Institute of Pharmaceutical Education and Research, Maharashtra, Pune, 411019, India; Nizam A., 4 Department of Chemistry, CHRIST (Deemed to be University), Karnataka, Bengaluru, 560029, India; Sahoo R.K., 5 School of Pharmacy and Life Sciences, Centurion University of Technology and Management, Odisha, Bhubaneswar, 752050, India; Bendale A.R., 6 Sandip Institute of Pharmaceutical Sciences, Maharashtra, Nashik, 422213, India; Khairnar S.J., 7 MET Institute of Pharmacy, Bhujbal Knowledge City, Maharashtra, Nashik, 422003, India; Jagtap M.R., 8 JMCT Institute of Pharmacy, Maharashtra, Nashik, 422006, India