A simple and efficient synthesis of imidazoquinoxalines and spiroquinoxalinones via pictect-spengler reaction using Wang resin
imidazoquinoxaline; recyclable catalyst; spiroquinoxalinones; Wang-OSO3H
An efficient approach for the synthesis of various imidazoquinoxalines and spiroquinoxalinones has been reported from 2-(1H-imidazol-1-yl) aniline and different aldehydes using Wang-OSO3H as a reusable catalyst to get in good yields. The reaction condition has been optimized by screening in various solvents and a gram scale experiment has also demonstrated. Further, the substrate scope of the reaction has also been well demonstrated. 2021 Taylor & Francis Group, LLC.
Gorle S.; Vaikunta Rao L.; Chiranjeevi Y.; Dhanunjaya Rao A.V.; Mekala R.; Tadiparthi K.; Raghunadh A.
Synthetic Communications, Vol-52, No. 2, pp. 218-228.
Gorle S., Technology Development Centre, Custom Pharmaceutical Services, Dr. Reddys Laboratories Ltd, Hyderabad, India, Department of Chemistry, GIS, GITAM (Deemed to be University), Visakhapatnam, India; Vaikunta Rao L., Department of Chemistry, GIS, GITAM (Deemed to be University), Visakhapatnam, India; Chiranjeevi Y., Technology Development Centre, Custom Pharmaceutical Services, Dr. Reddys Laboratories Ltd, Hyderabad, India; Dhanunjaya Rao A.V., Technology Development Centre, Custom Pharmaceutical Services, Dr. Reddys Laboratories Ltd, Hyderabad, India; Mekala R., Technology Development Centre, Custom Pharmaceutical Services, Dr. Reddys Laboratories Ltd, Hyderabad, India; Tadiparthi K., Department of Chemistry, CHRIST (Deemed to be University), Bangalore, India; Raghunadh A., Technology Development Centre, Custom Pharmaceutical Services, Dr. Reddys Laboratories Ltd, Hyderabad, India