Extricating the Association Between the Prognostic Factors of Colorectal Cancer
Colorectal cancer; Haematology; Lymph node metastasis; Staging
Purpose: Colorectal cancer (CRC) is one of the recurring and lethal gastrointestinal tract disease rankings as the primary cause of worldwide morbidity and mortality. In general, the tumour node metastasis (TNM) and Dukes classification assist in diagnosis, prognosis and treatments of CRC along with haematological examinations and tumour demographic characterisations in patients. Methods: The present investigation is carried out on clinically acknowledged sixty-five CRC patients based on haematological findings and are sorted into stages using TNM and Dukes. The present study is to find the association between haematological findings, demographic characters, differentiation position, lymph node invasion and tumour node metastasis in CRC patients in accordance with their age. Results: We observed significant (p < 0.05) nexus between lymph node metastasis and tumour node metastasis on the basis of tumours differentiation demographic positioning and age of the individuals. Conclusion: Earlier location tracing and medicinal treatment or surgery lessen the chance of CRC morbidity and mortality along with prolonging survival rate via prognostic factors and disease position determination. 2020, Springer Science+Business Media, LLC, part of Springer Nature.
Mohd Y.; Balasubramanian B.; Meyyazhagan A.; Kuchi Bhotla H.; Shanmugam S.K.; Ramesh Kumar M.K.; Pappusamy M.; Alagamuthu K.K.; Keshavarao S.; Arumugam V.A.
Journal of Gastrointestinal Cancer, Vol-52, No. 3, pp. 1022-1028.
Mohd Y., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, School of Life Sciences, Bharathiar University, Coimbatore, 641046, Tamil Nadu, India; Balasubramanian B., Human Genetics Laboratory, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, 461046, Tamil Nadu, India, Department of Food Science and Biotechnology, College of Life Science, Sejong University, Seoul, 05006, South Korea; Meyyazhagan A., Human Genetics Laboratory, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, 461046, Tamil Nadu, India, Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560029, Karnataka, India; Kuchi Bhotla H., Human Genetics Laboratory, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, 461046, Tamil Nadu, India; Shanmugam S.K., Human Genetics Laboratory, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, 461046, Tamil Nadu, India, Department of Animal Resource and Sciences, Dankook University, Cheonan, South Korea; Ramesh Kumar M.K., Department of General Surgery, Mahatma Gandhi Medical College and Research Institute, Pillaiyarkuppam, Pondicherry, 607403, India; Pappusamy M., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560029, Karnataka, India; Alagamuthu K.K., Human Genetics Laboratory, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, 461046, Tamil Nadu, India, Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing, 210023, China; Keshavarao S., Human Genetics Laboratory, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, 461046, Tamil Nadu, India; Arumugam V.A., Medical Genetics and Epigenetics Laboratory, Department of Human Genetics and Molecular Biology, School of Life Sciences, Bharathiar University, Coimbatore, 641046, Tamil Nadu, India