Anti-vibrio effects of the precious Tibetan pill, Rinchen Drangjor Rilnag Chenmo (RDRC)

Title

Anti-vibrio effects of the precious Tibetan pill, Rinchen Drangjor Rilnag Chenmo (RDRC)

Creator

Dhargyal S.; Philip I.; Biswas S.; Sarojini S.

Description

Tibetan precious pills are an integral part of TTM (Traditional Tibetan Medicine). Among them, Rinchen Drangjor Rilnag Chenmo (RDRC) has been named King of Precious Pills due to its efficacy in treating a multitude of human disorders. RDRC has a complex formulation with about 140 ingredients, mostly from medicinal plants and a few precious stones and metals. Not many studies have been done on the experimental validation of antimicrobial properties of this important pill. The current study investigated the antimicrobial activity of the extracts of RDRC. Both aqueous and chloroform extracts were evaluated for their antibacterial potential against a total of seven different bacterial species, which are pathogenic, including three species of Vibrio, viz. V. vulnificus, V. parahaemolyticus and V. harveyi using the well-diffusion method and also by assessing MIC and MBC values. Its antifungal potential was also studied against two fungal strains Aspergillus Niger and Talaromyces islandicus. It was found that the chloroform extract of RDRC exerted a positive antibacterial effect on all the Vibrio species tested, and the least MIC of 3.33 mg/ml was observed for V. parahaemolyticus. This is the first study of its kind on the anti-Vibrio effect of the Tibetan precious pill, Rinchen Drangjor Rilnag Chenmo. Dhargyal et al (2021). This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited (https://creativecommons.org/licenses/by/4.0/).

Source

Plant Science Today, Vol-8, No. 3, pp. 681-687.

Date

2021-01-01

Publisher

Horizon e-Publishing Group

Subject

Antibacterial activity; Antifungal effect; Minimum bactericidal concentration (MBC); Minimum inhibitory concentration; Rinchen Drangjor Rilnag Chenmo

Coverage

Dhargyal S., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore 29, India; Philip I., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore 29, India; Biswas S., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore 29, India; Sarojini S., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore 29, India

Rights

All Open Access; Gold Open Access; Green Open Access

Relation

ISSN: 23481900

Format

Online

Language

English

Type

Article

Identifier

https://doi.org/10.14719/PST.2021.8.3.1225

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111312211&doi=10.14719%2fPST.2021.8.3.1225&partnerID=40&md5=da92dadc294c01c7de3d7d6445840c2f