Heavy metal stress influence the andrographolide content, phytochemicals and antioxidant activity of Andrographis paniculata
- Title
- Heavy metal stress influence the andrographolide content, phytochemicals and antioxidant activity of Andrographis paniculata
- Creator
- Antony A.; Nagella P.
- Description
- Heavy metals (HM) are toxic components present in the earth's crust that can have a negative impact on plants as well as animals. Andrographis paniculata or 'King of bitters' belonging to the family Acanthaceae, is a medicinal herb traditionally used in the treatment of fever, common cold etc. In the present study, the effect of heavy metals (copper, tin and cobalt) on the andrographolide content, biochemical parameters like chlorophyll, carotenoid, protein, Total phenolic content (TPC), Total flavonoid content (TFC) and antioxidant activity in A. paniculata were analysed. Saplings of A. paniculata were treated at 50 and 100 mM concentrations, three different times at a time interval of 7 days. Andrographolide production was found to increase in copper and cobalt treated saplings when compared with the control. From the results, maximum andrographolide concentration was found in the saplings treated with 50 mM copper (8.51 mg/gm of DW) and 50 mM tin (8.10 mg/gm of DW) respectively. 50 mM cobalt treated plants have shown the highest concentration of TPC (17.21 mg/g of extract) and TFC (6.97 mg/gm of extract). Notable variations in other biochemical parameters like total chlorophyll, carotenoid content and antioxidant activities were observed in all treatments compared with the control. Antony & Nagella (2021). This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited (https://creativecommons.org/licenses/by/4.0/).
- Source
- Plant Science Today, Vol-8, No. 2, pp. 324-330.
- Date
- 2021-01-01
- Publisher
- Horizon e-Publishing Group
- Subject
- Andrographis paniculata; Andrographolide; Cobalt; Copper; Tin; Total flavonoids content; Total phenolic content
- Coverage
- Antony A., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560 029, India; Nagella P., Department of Life Sciences, CHRIST (Deemed to be University), Bangalore, 560 029, India
- Rights
- All Open Access; Gold Open Access
- Relation
- ISSN: 23481900
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Antony A.; Nagella P., “Heavy metal stress influence the andrographolide content, phytochemicals and antioxidant activity of Andrographis paniculata,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 26, 2025, https://archives.christuniversity.in/items/show/15801.