Aza-Michael addition of 1,2-diazoles to structurally diverse enones: Efficient methods toward ?-amino ketones
- Title
- Aza-Michael addition of 1,2-diazoles to structurally diverse enones: Efficient methods toward ?-amino ketones
- Creator
- Polina S.; Putta V.P.R.K.; Gujjarappa R.; Pujar P.P.; Malakar C.C.
- Description
- An efficient and mild protocol was realized using 1,2-diazoles and related heterocycles with cyclic and acyclic enones in presence of T3P (2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide) toward the regioselective formation of N-cycloalkyl heterocycles at room temperature. The developed reaction conditions showcased good selectivity over a wide range of 1,2-diazoles and enones by delivering N-cycloalkyl heterocycles in excellent yields. 2020 Wiley Periodicals LLC.
- Source
- Journal of Heterocyclic Chemistry, Vol-58, No. 4, pp. 1029-1033.
- Date
- 2021-01-01
- Publisher
- HeteroCorporation
- Subject
- 1,2-diazoles; aza-Michael addition; cyclic enones; N-cycloalkyl heterocycles; T3P-mediated
- Coverage
- Polina S., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India; Putta V.P.R.K., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India; Gujjarappa R., Department of Chemistry, National Institute of Technology Manipur, Imphal, India; Pujar P.P., Department of Chemistry, CHRIST (Deemed to be University), Bengaluru, India; Malakar C.C., Department of Chemistry, National Institute of Technology Manipur, Imphal, India
- Rights
- Restricted Access
- Relation
- ISSN: 0022152X; CODEN: JHTCA
- Format
- Online
- Language
- English
- Type
- Article
Collection
Citation
Polina S.; Putta V.P.R.K.; Gujjarappa R.; Pujar P.P.; Malakar C.C., “Aza-Michael addition of 1,2-diazoles to structurally diverse enones: Efficient methods toward ?-amino ketones,” CHRIST (Deemed To Be University) Institutional Repository, accessed February 27, 2025, https://archives.christuniversity.in/items/show/15809.